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Pyruvate oxidation, pyruvate => acetyl-CoA |
| Entry | shk_M00307 (complete) |
| Name | Pyruvate oxidation, pyruvate => acetyl-CoA |
| Definition |
((K00163,K00161+K00162)+K00627+K00382-K13997),K00169+K00170+K00171+(K00172,K00189),K03737 |
| Type | Pathway module |
| Organism | Streptomyces huasconensis D23 |
| Pathway | shk00010 shk00020 shk00620 shk00785 shk01200 shk01210 shk01100 |
| Reaction | R00209,R01196 C00022 -> C00024 R00014 C00022 + C00068 -> C05125 R03270 C05125 + C15972 -> C16255 + C00068 R02569 C16255 -> C00024 + C15973 R07618 C15973 -> C15972 |
| RModule | RM044 2-Oxocarboxylic acid conversion to its CoA derivative |
| Comment | The oxidative decarboxylation of pyruvate to acetyl-CoA is catalyzed by the pyruvate dehydrogenase complex as part of aerobic respiration or by pyruvate:ferredoxin oxidoreductase [EC:1.2.7.1]. |