+E Replication protein KO
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DNA Replication Proteins - Gloeobacter kilaueensis
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D GKIL_2060 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D GKIL_0880 dcm; DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D GKIL_2985 dcm; DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D GKIL_0605 dcm; DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D GKIL_2140 hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D GKIL_0766 hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D GKIL_3287 ihfB; histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D GKIL_0001 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein
D GKIL_3423 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D GKIL_2972 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D GKIL_0016 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D GKIL_2373 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D GKIL_2372 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D GKIL_0250 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E GKIL_3101 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E GKIL_1742 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E GKIL_1270 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E GKIL_4416 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E GKIL_4255 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E GKIL_2019 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E GKIL_2060 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E GKIL_0117 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E GKIL_3584 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E GKIL_2060 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E GKIL_0117 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
D GKIL_0434 dam; D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D GKIL_0881 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D GKIL_0632 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
B DNA Topoisomerases
C GKIL_3628 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C GKIL_3219 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C GKIL_3491 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C GKIL_3661 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C GKIL_2064 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C GKIL_3693 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022