Verrucosispora sp. NA02020: HUT12_27150
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Entry
HUT12_27150 CDS
T06958
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ver
Verrucosispora sp. NA02020
Pathway
ver00020
Citrate cycle (TCA cycle)
ver00630
Glyoxylate and dicarboxylate metabolism
ver00785
Lipoic acid metabolism
ver01100
Metabolic pathways
ver01110
Biosynthesis of secondary metabolites
ver01120
Microbial metabolism in diverse environments
ver01200
Carbon metabolism
ver01210
2-Oxocarboxylic acid metabolism
Module
ver_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ver_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ver00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
HUT12_27150
00630 Glyoxylate and dicarboxylate metabolism
HUT12_27150
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HUT12_27150
Enzymes [BR:
ver01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
HUT12_27150
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
HUT12_27150
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
HUT12_27150
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
HUT12_27150
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
SHOCT-like_DUF2089-C
Motif
Other DBs
NCBI-ProteinID:
QKW16062
UniProt:
A0A7H8KJA1
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All DBs
Position
6094102..6097851
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AA seq
1249 aa
AA seq
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MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDPAWHDFFADYRPGPGKGRSADGD
GPATTTESAPKAPAKTEPSAAKSEPSAKATPAAKAEPAKSTAPAKAKPAAKSEPAKATTT
KSIPAKSAPTATGPQTTPLRGVAARIVQNMDASLAVPTATSVRAVPAKLLVDNRIVINNH
LARGRGGKVSFTHLVGYALVRAMVAHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLAKPD
GSRTLVVPSIKGCEQMDFRQFWQAYEDVVRRARRNELTMDDYSGTTISLTNPGGIGTVHS
MPRLMQGQSAIIGVGAMEYPAPYQGMSEATLAELAVSKVITLTSTYDHRIIQGAQSGEFL
KVMHELLLGEHGYYDQIFTSLRIPYEPVRWMRDVAVDSEGQINKTARVHELIHSYRVRGH
LMADTDPLEFKIRKHPDLDVLQHGLTLWDLDRTFPVNGFNGRQRMRLREILGVLRDSYCR
RVGIEYMHIQDPAERRWIQERVERKYEKPPADEQKHVLNRLNAAEAFETFLQTKYVGQKR
FSLEGGESLIPLLGEVLEASAENDLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEGHL
DPRSTQGSGDVKYHLGQNGKFTTPAGDHSVKVSVVANPSHLEAVDPVLEGIVRAKQDRID
LKLEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEYS
RSSLYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQTFNKDVVIDLVCYRRRGHNE
GDDPSMSNPQMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQAQLERVFKATRD
AASTPRQVSRPARQDEPEPQVETATDASVVKAVGEAHVNLPDGFTPHKRIQQLLDRRARM
SVEGNIDWGFGEIIAFGALLHDGVTVRLAGQDSRRGTFVQRHASIVDAETGDDYLPLQSL
TGDGERSRLFVHDSLLSEYAAMGFEYGYSVENLNALVCWEAQFGDFVNGAQSVIDEFISS
GEVKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVAIPTTPANYFHLLRR
QALSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFAPVLADQAAPAADQVKRVLLCSGK
VYYDLFQARQERGVTDTALIRLEQLYPMPVEEIRAALAQYPNAEDFAWVQEEPANQGSWS
FVALNLLEHLDGVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgctacctcgccgatcccagcagcgtcgacccggcctgg
cacgacttcttcgccgactaccggcccggccccggcaagggccgctccgccgacggtgac
ggcccggcgaccaccaccgagtccgccccgaaggccccggccaagactgagccgagtgcc
gccaagtccgagccgagcgccaaggccacacccgcggccaaggcggagccggccaagtcc
acggcaccggcgaaggccaagccggccgccaagtccgagccggccaaggcgaccacgacg
aagtccatcccggcgaagtcggccccgaccgccaccgggccgcagaccacgccgctgcgc
ggcgtcgccgcccggatcgtgcagaacatggacgcctcactggccgtgccgaccgcgacc
agcgtgcgcgcggtgccggccaagctgctggtcgacaaccgcatcgtgatcaacaaccac
ctcgcccgagggcgcggcggcaaggtcagcttcacccacctggtcggctacgcgctggtc
cgggcgatggtcgcgcacccggagatgaacaactccttcgccgaggtcgacggcaaaccg
gcgatggtccgccccgagcacgtcaacctgggcatcgccatcgacctggccaagcccgac
ggcagccggaccctggtggtgccctccatcaagggttgcgagcagatggacttccggcag
ttctggcaggcgtacgaggacgtggtccggcgggcccgccgcaacgaactgaccatggac
gactactccggcaccaccatctcgctgaccaaccccggcggcatcggcaccgtgcactcg
atgccgcgcctgatgcagggccagagcgcgatcatcggcgtcggcgcgatggagtacccg
gcgccgtaccagggcatgagcgaggccaccctcgccgagctggcggtcagcaaggtcatc
acgctgaccagcacgtacgaccaccggatcatccagggcgcgcagtccggcgagttcctc
aaggtcatgcacgagctgctgctcggcgagcacggctactacgaccagatcttcacctcg
ctgcgcatcccgtacgagccggtgcgctggatgcgcgacgtcgcggtcgacagcgagggg
cagatcaacaagaccgcgcgggtgcacgagctgatccactcctaccgggtccggggccac
ctgatggccgacaccgacccgctggagttcaagatccgcaagcaccccgacctggacgtc
ctccagcacgggctgaccctgtgggacctggaccgcaccttcccggtgaacggcttcaac
ggccggcagcggatgcggctgcgggagatcctcggggtgctgcgcgactcgtactgccgc
cgggtcggcatcgagtacatgcacatccaggacccggccgagcgccgctggatccaggag
cgggtcgagcgcaagtacgagaagccgccggccgacgagcagaagcacgtgctgaaccgg
ctcaacgcggccgaggctttcgagacgttcctgcagaccaagtacgtcgggcagaagcgc
ttctcgctggagggcggcgagtcgctgatcccgctcctcggcgaggtgctggaggcgtcc
gccgagaacgacctggacgaggtcgtgatcggcatggcccaccggggtcgtctcaacgtg
ctggccaacatcgtcggcaagccgtacgagaagatcttctcggagttcgaggggcacctc
gacccgcgctccacccagggttccggcgacgtgaaataccacctgggccagaacggcaag
ttcaccacgccggccggtgaccactcggtcaaggtctcggtggtggcgaacccgtcgcac
ctggaggcggtcgacccggtgctggagggcatcgtccgcgccaagcaggaccgcatcgac
ctcaagctggagggctacacagtgctgccgctggcggtgcacggcgacgccgccttcgcc
ggtcagggtgtggtggccgaaacgctcaacctctcccagctgcgcggctaccgcaccggt
gggaccgtgcacgtggtggtcaacaaccaggtcggcttcaccaccgcgccggagtactcc
cggtccagcctctacagcaccgacgtggcgcggatgatccaggcgccgatcttccacgtc
aacggcgacgaccccgaggccgtggtccgggtcgcccggctggccttcgagtaccggcag
acgttcaacaaggacgtcgtgatcgacctggtctgctaccggcggcgcgggcacaacgag
ggcgacgacccctcgatgtccaacccccagatgtacaagatcattgactcgaagcgctcg
gtccgcaagctctacaccgaggagctgatcgggcggggtgacatcaccgtcgaggacgcc
gaggagctgctgcgcgactaccaggcgcagttggagcgggtcttcaaggccacccgcgac
gcggccagcaccccgcgccaggtcagccgcccggcccggcaggacgagccggagccgcag
gtggagaccgcgaccgacgcgtcggtggtcaaggccgtcggcgaggcgcacgtcaacctg
ccggacggcttcaccccgcacaagcggatccagcagttgctcgaccggcgggcccggatg
tccgtcgagggcaacatcgactggggcttcggcgagatcatcgccttcggggcactgctg
cacgacggggtcaccgtccggctcgccggacaggactcccggcgcggcaccttcgtgcaa
cggcacgcctcgatcgtggacgccgagaccggtgacgactacctgccgttgcagtcgctg
accggcgacggcgagcggtcccggctcttcgtgcacgactcgctgctctccgagtacgcc
gcgatgggcttcgagtacggctactcggtggagaacctgaacgcgctggtctgctgggag
gcccagttcggcgacttcgtcaacggcgcccagtcggtgatcgacgagttcatctcctcc
ggtgaggtgaagtggggccagcgctccgcggtcaccctgctgctgccgcacggccacgag
ggacagggcccggaccacacctccggccggcccgagcggttcctccagctctgcgccgag
gacaacatgcgggtggccatcccgaccaccccggcgaactacttccacctgctgcgtcgc
caggccctctcgccgaagcgcaagccgctggtggtgttcacgccgaagtccctgctgcgg
cacaagctctgcgtctccccggtcgaggacttcaccaccggcaccttcgcaccggtcctg
gccgaccaggcggcacccgccgccgatcaggtcaagcgggtgctgctctgctcgggcaag
gtctactacgacctgttccaggcgcggcaggagcgcggcgtcaccgacaccgcgctgatc
cggctggagcagctctacccgatgccggtggaggagatccgggccgcgctcgcccagtac
ccgaacgcggaggacttcgcctgggtgcaggaggagccggccaaccagggttcctggtcg
ttcgtcgcgctcaacctgctggagcacctcgacggggtccgcctgcgtcgcatctcccgc
cccgccgccgccgccccggccgtcggctcggcgaagatgcacgaggtggagcagaacgcg
ctcatcgaggcggcgctgccccgcccctga
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