Ursus maritimus (polar bear): 103677383
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Entry
103677383 CDS
T03271
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00280
Valine, leucine and isoleucine degradation
umr00640
Propanoate metabolism
umr00785
Lipoic acid metabolism
umr01100
Metabolic pathways
umr01210
2-Oxocarboxylic acid metabolism
Module
umr_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
103677383 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
103677383 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103677383 (BCKDHA)
Enzymes [BR:
umr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
103677383 (BCKDHA)
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Paralog
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
103677383
NCBI-ProteinID:
XP_008704863
UniProt:
A0A384DCX2
LinkDB
All DBs
Position
Unknown
AA seq
446 aa
AA seq
DB search
MAVAAAAARVWGSSRGLDRAGLLLLRRPGARGLARSLPRRQEQQHFPSLDDKPQFPGASA
EFIDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVLKFYRSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKPKPSPSLLFSDVYQEMPAQ
LRKQQEALARHLQTYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgcagcagcgagggtctggggctcgagtcgaggcttggaccgggct
ggcctcctgctcctgcggcggcctggggctcgggggctggctagatctctgccccggaga
caggagcagcagcacttcccatccctggatgacaagccccagttcccgggggcctcggcg
gagttcatagacaagctagaattcatccagcccaatgtcatctccgggatccccgtctac
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccatctgccccag
gagaaggtgctcaagttctataggagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccgaatctccttctacatgactaactatggcgaggagggg
acgcacgtggggagcgcagcagcgctggacaacacggacctggtgtttggccagtaccgg
gaggcaggtgtgctcatgtaccgggactaccccctggagctgttcatggcccagtgctac
ggcaacgtcagtgacctgggcaagggccgccagatgcccgtgcactacggctgcagggag
cgccactttgtcaccatctcctctccgctggccacgcagatcccgcaggcggtgggagcg
gcctacgcagccaagcgggccaacgccaacagggtggtcatctgctacttcggggagggg
gcggccagcgagggggacgctcacgccggcttcaacttcgctgccaccctcgagtgcccc
atcatcttcttctgccgcaacaacggctatgccatctccacgcccacgtcggagcagtac
cgcggggacggcatcgctgcccgaggcccaggctatggcatcatgtccatccgtgtggat
ggcaacgacgtgtttgccgtgtacaacgccaccaaggaggcccggcggcgggcggtggcc
gagaaccagcccttcctcatcgaggccatgacctacaggatcgggcaccacagcactagt
gatgacagctcagcctaccgctcggtggacgaggtcaattactgggacaagcaggaccac
cccatctctcgcctgcgccactacctgcagagccggggctggtgggacgacgagcaggag
aaggcctggaggaagcagtcccgaaagaaggtgatggaggcctttgagcaggcggagcgg
aagccgaagcccagccccagcctgctcttctccgacgtgtaccaggagatgcccgcccag
ctccgcaagcagcaggaggccctggcccggcacctgcagacctacggggagcactacccc
ctggaccactttgagaagtga
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