Treponema pallidum subsp. pallidum SS14: TPASS_0446
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Entry
TPASS_0446 CDS
T00716
Symbol
gcpE
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
tpp
Treponema pallidum subsp. pallidum SS14
Pathway
tpp00900
Terpenoid backbone biosynthesis
tpp01100
Metabolic pathways
tpp01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
tpp00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
TPASS_0446 (gcpE)
Enzymes [BR:
tpp01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
TPASS_0446 (gcpE)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
TPASS_0446 (gcpE)
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Motif
Pfam:
GcpE
Motif
Other DBs
NCBI-ProteinID:
ACD70871
UniProt:
A0A0H3BIW8
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Position
473747..474961
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AA seq
404 aa
AA seq
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MDSSAGVSPCNSPYGSGLLDVPLKLRPRASHYRARSLVIGGKEHVRALPLGGDAPIPIQT
MWKEPLIGADLQSIVDRLLELEQLGCDVVRFAVPDRESAELFVALCARTRMPLVADIHFD
YRLALRCMDGPVAKVRINPGNIGVRERVRAVVEKARATGTALRIGVNTGSLPGVVKRAVA
ARYADGMQSVNARAEALVQTAFAEAAYLDQLHFDRVVLSLKASTVAETVRANELFAQQSD
IPLHLGVTEAGPLVSGIVKSTLAFSQLLSRNIGATVRVSLSDSMEHEVLAAREILAECGK
RAGGVRLVSCPRCGRIGFDVHAFVRRWQKELFSLKKDITVAVMGCVVNGPGEGKHADLGI
SGAEDSVIFFKRGKIVRRIQVRDLCADERTRIIDAAFKEELSSL
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
gtggattcatctgccggtgtgtctccctgcaatagtccgtatgggagtggacttttggat
gttccattaaaattaagaccgcgtgcgtcccactaccgtgcacgatcattggtaattgga
ggaaaggaacatgtgcgtgcgttgcctcttgggggtgacgcaccgattcctatccaaaca
atgtggaaagaaccgctcattggtgcagatctccaatccattgtggaccgtcttttggaa
cttgaacaattagggtgtgacgttgtgcgttttgccgttcctgacagggaatcggctgag
ctttttgtggcgctttgcgcgcgcacgcgtatgccgcttgttgcagacattcactttgat
taccggcttgcgctgcggtgtatggacggaccggtagcgaaagtgcgtattaacccgggg
aatatcggtgtgcgtgagcgcgtgcgtgcggtggtagaaaaggctcgagcaaccggcact
gctttgcgtattggggtgaataccggttctctgccgggtgtggtgaagcgcgcagttgcg
gcgcgttacgcggatgggatgcagtcagtgaatgcgcgtgcagaagcgttggtgcaaact
gcctttgcagaagctgcgtatctagatcagttacactttgatcgggttgtcctttctctg
aaggcttctacggttgcagagacggtacgtgccaacgaactttttgcgcagcagtctgat
attcccttgcaccttggagtaacagaagcaggcccgcttgtttccggtattgtcaaaagt
acacttgcattttcccaattactgtcacgcaatattggtgccacggtgcgggtgagtctt
tcagatagcatggagcatgaggtgctggctgcgcgagaaattcttgctgaatgcggtaaa
cgggctggtggggttcgtttagtgtcatgtccgcgctgtggcaggattggttttgacgta
cacgcatttgtgcggaggtggcaaaaggaactgttcagtttgaaaaaggatatcacggtt
gcggttatgggctgtgtagtgaatggtcctggagaaggaaagcatgcggatctcggtatc
agcggtgcggaggattcggtgattttttttaagcggggaaagatagtgcgtcgcattcag
gtacgtgatctttgcgcagacgagcgcacgcgcataatagacgcagcgtttaaagaggaa
ttgtcaagtttatga
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