Talpa occidentalis (Iberian mole): 119244232
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Entry
119244232 CDS
T07495
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00020
Citrate cycle (TCA cycle)
tod00480
Glutathione metabolism
tod01100
Metabolic pathways
tod01200
Carbon metabolism
tod01210
2-Oxocarboxylic acid metabolism
tod01230
Biosynthesis of amino acids
tod04146
Peroxisome
tod05230
Central carbon metabolism in cancer
Module
tod_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tod_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
119244232 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
119244232 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
119244232 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119244232 (IDH2)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
119244232 (IDH2)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
119244232
NCBI-ProteinID:
XP_037365791
LinkDB
All DBs
Position
Unknown
AA seq
452 aa
AA seq
DB search
MAGCWRVARALRRAAGSGPAWASAAPLGPSSPAQPRRHYADKRIKVANPVVEMDGDEMTR
IIWQFIKDKLILPHVDVQLKYFDLGLPHRDQTNDQVTVDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTEPIVIGRHAHGDQYK
CTDFLVDGAGSFKIIFTPKGGGRAQEWEVYDFPAGGVGLGMYNTDESISGFAHSCFQYAV
QKKWPLYLSTKNTILKAYDGRFKDIFQAIFEKHYKAEFDKSKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQELVRFAQTLEKVCVNTVESGAMTKDLAGCIH
GLSNVKLNEHYLNTSDFLDTIKSNLDKALGRQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggcgggctgctggcgggtggcgcgcgcgctgcgcagggcggcgggctcggggccggcc
tgggcctccgccgcgccgctgggccccagctcgcccgcgcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaaccccgtggtggagatggacggcgacgagatgacccgc
atcatctggcagttcatcaaggacaagctcatcctgccccacgtggacgtccagctcaag
tattttgacctggggctcccgcaccgtgaccagaccaacgaccaggtcaccgtcgactcc
gcgctggccacccagaagtacagcgtggctgtcaaatgcgccaccatcacccctgacgag
gcccgcgtggaagagttcaagctgaagaagatgtggaagagccccaatggaaccatccgg
aacatccttggggggacggtcttccgggagcccatcatttgcaaaaacatcccccgtctg
gtccccggctggaccgagcccatcgtcatcggcaggcatgcccatggcgaccagtacaag
tgcacggattttctggtcgacggggctggctccttcaagataatcttcaccccgaagggc
ggcggccgcgcccaggagtgggaggtgtacgacttccccgcgggcggcgtgggcctgggc
atgtacaacacggacgagtccatctccggctttgcgcacagctgcttccagtacgccgtc
cagaagaagtggccgctctacctgagcaccaagaacaccatcctgaaggcctacgacggg
cgcttcaaggacatcttccaggccatctttgagaagcactacaaggcggagttcgacaag
agcaagatctggtacgagcaccggctcatcgacgacatggtggcgcaggtgctcaagtct
tcgggcggcttcgtgtgggcctgcaagaactacgacggggacgtgcagtctgacatcctg
gcccagggcttcggctccctgggcctgatgacgtccgtgctggtctgcccggatgggaag
accatcgaggcggaggcagcccacgggacggtcacccgtcactaccgggagcaccagaag
ggccggcccaccagcaccaaccccatcgccagcatcttcgcttggacgcgaggcctggag
caccgggggaagctggacgggaaccaggagctcgtcaggtttgcccagaccctggagaag
gtgtgtgtgaacacggttgagagcggagccatgaccaaggacctggcgggctgcatccac
ggcctcagcaacgtgaagctcaacgagcactacctgaacacctcggacttcctggacacc
atcaagagcaacctggacaaggcgctgggccggcagtag
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