KEGG   Sturnus vulgaris (common starling): 106850203
Entry
106850203         CDS       T08833                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
svg  Sturnus vulgaris (common starling)
Pathway
svg00670  One carbon pool by folate
svg01100  Metabolic pathways
svg01240  Biosynthesis of cofactors
svg04981  Folate transport and metabolism
Module
svg_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:svg00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    106850203 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    106850203 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:svg04147]
    106850203 (MTHFD1)
Enzymes [BR:svg01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     106850203 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     106850203 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     106850203 (MTHFD1)
Exosome [BR:svg04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   106850203 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH DUF6507
Other DBs
NCBI-GeneID: 106850203
NCBI-ProteinID: XP_014726836
LinkDB
Position
Unknown
AA seq 935 aa
MAPAEILSGKIVSGQVRDRLKQQVVEMTEKFPGFRPGLAILQVGNRDDSNLYINMKLKAA
AEIGISANHIKLPNTATEADVLKCIASLNADPAVHGFIVQLPLDSNKPINTEKITNAVAP
EKDVDGLSSINAGKLSRGDLGDCFIPCTPKGCMELIRQTGVQVAGKRAVVIGRSKIVGAP
MHDLLLWNNATVTTCHSKTSTLAEEVGKADILVVAAGRAEMVKGEWIKPGAIVIDCGINH
VPDSTKPSGKRVVGDVAYSSAKEKASFITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQP
GKWTIQYNQLTLQMPVPSDIEISKSCMPKPIEQVAKEVGLFPDEVELYGQTKAKVQLSAL
KRLQNQPDGKYVVVTGITPTPLGEGKSTTTVGLVQALGAHLHQNVFACVRQPSQGPTFGI
KGGAAGGGYCQVVPMEEFNLHLTGDIHAITAANNLVAAAIDARMFHELTQSDQALYNRLV
PSVNGVRKFSDIQIRRLQKLGINKTDPMALTKEEINAFVRLDIDPGTITWQRVLDTNDRF
LRKITIGQSVTEKGFSRTAQFDITVSSEIMAVLALADGLDDMKKRFGRMVVASSKKGQPV
TADDLGVTGALAVLMKDAVKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVG
KDGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPAVTAGVPLP
KEYTEENLQLVAKGCSNLNKQIQNARMFGVPVVVAVNAFKTDTKAELALVVQHAKEAGAF
DAVECTHWAEGGKGALALARAVQRASQAPSNFRFLYNVELPVVDKIRLIAQQVYGAKDIE
LLPEAQEKVALYTKQGFGNLPICMAKTHLSLSHDPEQKGAPTGFILPIRDIRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDSVSGEVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcccccgccgagatcctcagcggcaagattgtctccggacaagtgagagacagacta
aagcagcaagttgttgagatgactgagaaatttccaggcttcagaccaggacttgccatt
ttgcaggttggaaatcgggatgattcaaacctctacattaacatgaagctgaaggctgct
gctgagattgggatcagtgccaaccacataaaattgccaaacacagcaacagaagctgat
gtgctcaagtgcattgcctctctgaatgcagacccagctgttcatggatttatagtgcag
ctgccgctcgactccaataaacccatcaacacagaaaaaataaccaatgctgttgcacct
gagaaggatgtggatggcttaagtagcatcaatgctgggaaactctctagaggagacctt
ggagactgctttattccgtgtacgccaaagggatgcatggaactcatcaggcagacaggt
gtccaggtggcagggaaaagagccgtggtgatcggtcgcagtaagatcgtgggtgctccc
atgcacgacctgctgctctggaataatgcaacagtcaccacgtgccattccaagacctcc
accctggctgaggaggttggcaaagctgacatcctggtggttgcagctggtagagctgaa
atggtaaaaggtgaatggatcaagcctggtgcaatcgtaatagactgtggaattaaccat
gttccagacagcacaaagcccagtggaaaaagagttgtgggagatgtggcatacagttca
gcaaaggaaaaagcttccttcatcaccccagttcctggtggtgttgggcctatgactgtg
gccatgttaatgcagagcactgtggagagtgcccagcgttttctggagaagttccagcct
ggaaaatggactatccaatacaaccagcttaccctacagatgcctgttccaagtgatatt
gaaatctcaaagtcttgcatgcccaagcccattgaacaagttgcaaaagaagttggcctt
ttccctgatgaggtggagctctatggccaaactaaagccaaggttcagctctcagctctg
aagcgtctgcagaaccagccagatggcaaatacgtcgttgttactggaataactcccact
cccctgggagaagggaagagcaccaccactgttggtctggtccaagccttaggagcacac
cttcaccagaatgtctttgcctgtgttcggcagccttctcaggggccaacttttggcata
aaaggtggagctgcaggtggtggctattgtcaagttgtccccatggaagagtttaacctt
cacctcactggtgacatccatgccatcactgcagccaacaacctggtcgctgctgctatt
gacgcccgtatgttccacgagctgactcagtctgaccaggctctctacaaccgtttggtg
ccatctgtcaatggtgtcaggaagttctcagacattcagatccgaagactacagaaactg
ggcattaacaaaacagatcctatggctttgacaaaggaagaaataaatgcatttgtgaga
ctggacattgacccaggcaccattacgtggcaaagagtactggatacaaatgacagattc
cttaggaaaatcactattggacagtcggtgacagagaaaggcttctcacggacggctcag
tttgacatcacggtgagcagtgaaatcatggcagtcctagccctggctgatggcttggat
gatatgaaaaagcgatttggcagaatggtggtagcttccagcaaaaaaggacaaccagtt
acagcagatgaccttggagtaactggagctctggccgtcttgatgaaggatgctgtaaaa
ccaaacctcatgcagacattggagggaacaccagtgtttgttcatgctggaccttttgcc
aatattgcacatgggaattcctctgtgttggcagacaaaatagcattgaagcttgtgggt
aaagatggttttgttgttacagaagcaggatttggtgcagacataggcatggagaaattc
ttcaacattaagtgccgttattctggtctccggcctcatgtggtggtgttggttgctact
gtcagagctctgaaaatgcatggtggaggacctgcagtcactgctggggtacctttgcca
aaggaatacacagaagagaatcttcagctggtggcgaaaggctgcagcaacctaaacaag
caaatccagaatgcacggatgtttggtgtccccgtggtcgtggctgtcaatgctttcaag
acagatacaaaggctgagctggcccttgtagtacagcatgcaaaggaggcaggagcattc
gatgctgtggagtgcactcactgggcagagggaggaaaaggagctctggccctggcccga
gctgttcagagagcatcccaggcccctagcaacttcaggttcctctataatgtggagctg
cctgttgtagataagatcaggcttattgcccagcaggtctatggggcaaaagacattgag
ctacttccagaagcacaggagaaagttgccctgtacaccaagcagggatttggaaacctg
ccaatctgcatggctaaaactcacttgtcattgtctcatgaccctgaacaaaaaggagca
cctacaggtttcattctgccaatccgagacattcgggccagcgttggggctggattcttg
tatccgctggtggggacgatgagcactatgccaggacttcctacaagaccctgcttctat
gatatagacctggactcagtgtcaggagaagtaaatgggctcttctaa

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