KEGG   Streptomyces tsukubensis: B7R87_23205
Entry
B7R87_23205       CDS       T07155                                 
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
stsu  Streptomyces tsukubensis
Pathway
stsu00020  Citrate cycle (TCA cycle)
stsu00630  Glyoxylate and dicarboxylate metabolism
stsu00785  Lipoic acid metabolism
stsu01100  Metabolic pathways
stsu01110  Biosynthesis of secondary metabolites
stsu01120  Microbial metabolism in diverse environments
stsu01200  Carbon metabolism
stsu01210  2-Oxocarboxylic acid metabolism
Module
stsu_M00009  Citrate cycle (TCA cycle, Krebs cycle)
stsu_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:stsu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    B7R87_23205
   00630 Glyoxylate and dicarboxylate metabolism
    B7R87_23205
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    B7R87_23205
Enzymes [BR:stsu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     B7R87_23205
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     B7R87_23205
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     B7R87_23205
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     B7R87_23205
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh Transket_pyr OxoGdeHyase_C 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: AZK96455
LinkDB
Position
complement(5521341..5525222)
AA seq 1293 aa
MSSQSPSNANSPSLRPGGAPTADRGTPGQGPAAAFGANEWLVDEIYQQYLQDRDSVDRAW
WDFFADYKPGGKNTAEAPAEGAAAAPAAAASTAPAPATVPAPAPQQPAPVSAPAPAAQPA
PAAAPAAPAAPAAPAAKAPVAPAAPAAPAVKPPAAPAAKPAAAKAPEAAAPAGPELITLR
GPSAAVAKNMNASLEVPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGFAMV
QALRAMPSMNWSFAEKDGKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAAIKKAETLNFFE
FWQAYEDIVRRARSNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYP
AEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRVVANFLLGEEGFYDQIFEA
LRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDI
TEHGLTLWDLEREFAVGGFAGKSLMKLRDVLGVLRDSYCRTTGIEFMHIQDPKQRKWIQD
RVERPHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSA
AEARLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGT
FTGLDGEQIKVSLVANPSHLEAVDPVLEGVARAKQDVINKGGTDFTVLPVALHGDAAFAG
QGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVN
GDDPEACVRVARLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMVALIDKKRSV
RKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREATSHPAPTLVPDPQAEFPVAV
TTAVSQEVIKRIAESQVNIPDNITVHPRLLPQLQRRAASVEDGTIDWGMGETLAIGSLLM
EGTPVRLSGQDTRRGTFGQRHAVLVDQETNEDYTPLLYLTDEQARYNVYDSLLSEYAAMG
FEYGYSLARPESLVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQG
PDHSSARPERFLQMCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKA
AQSKTEEFLNGGFRPVIGDESVDPNAVRKVVFTSGKVYYDLDAERKKRGITDTAILRLER
LYPLPGAELQAEIAKFPNAEKYIWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERL
RRISRPHGSSPAVGSAKRHQAEQTQLVADVFDA
NT seq 3882 nt   +upstreamnt  +downstreamnt
gtgtcgtctcagtcccccagtaacgccaattcccccagccttcggccgggtggggccccc
acggccgaccgaggcacgccgggccagggccctgccgccgccttcggtgccaatgagtgg
ctcgtcgacgagatctaccagcagtacctccaggatcgcgattcggtagaccgcgcctgg
tgggacttcttcgccgactacaagcccggcgggaagaacaccgccgaggctccggccgag
ggtgctgccgcagccccggccgccgcggcatccaccgccccggctccggcgaccgtcccc
gctccggctccgcagcagccggccccggtgtccgctccggcaccggccgcgcagcccgct
ccggccgcggcgcccgccgccccggcagcccccgccgcacccgcggcgaaggcgcccgtg
gctccggctgcacccgcggcacccgcggtcaagccgcccgctgctccggcggcgaagccc
gccgcggccaaggcccccgaggccgcggctccggccgggcccgagctgatcaccctgcgc
ggcccctccgccgccgtcgcgaagaacatgaacgcctccctggaggtgcccacggccacg
tccgtgcgcgccgtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctgaagcgcgcccggggcgggaaggtctccttcacccacctcatcggcttcgccatggtg
caggccctgcgggccatgccgtcgatgaactggtcgttcgcggagaaggacggcaagccg
accctggtcaagccggagcacgtcaacttcggcctcgccatcgacctggtgaagccgaac
ggcgaccgccagctcgtcgtcgcggccatcaagaaggccgagaccctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtccgccgcgcccgcagcaacaagctgacgatggac
gacttcaccggcgtcaccgtctcgctgaccaaccccggcggcctcggcacggtccactcc
gtgccccggctgatgcccggccagtcggtgatcatgggcgtcggctccatggactacccc
gccgagttccagggcacctcccaggacaccctgaacaagctgggcatctccaaggtcatg
acgctgacctcgacctacgaccaccgggtcatccagggtgcggcgtccggcgagttcctg
cgcgtcgtggccaacttcctcctcggcgaggagggcttctacgaccagatcttcgaggcc
ctgcggatcccctacgagccggtccgctggctcaaggacatcgacgcgtcccacgacgac
gacgtcaccaaggccgcccgggtcttcgagctgatccactcctaccgggtccgtggccat
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctcgacatc
accgagcacgggctgaccctgtgggacctggagcgcgaattcgccgtcggcggtttcgcg
ggcaagtccctgatgaagctccgcgacgtcctcggcgtgctccgcgactcgtactgccgc
accaccggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatccaggac
cgggtcgagcgcccgcactccaagccggagcgcgaggagcagctgcggatcctgcgccgg
ctgaacgccgccgaggccttcgagaccttcctgcagacgaagtacgtcggccagaagcgg
ttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgcc
gccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccggctcaacgtc
ctcgccaacatcgtgggcaagtcgtacgcccagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcacc
ttcaccggtctcgacggcgagcagatcaaggtctccctggtcgccaacccctcccatctg
gaggccgtcgacccggtcctcgaaggcgtcgcccgcgccaagcaggacgtgatcaacaag
ggcggcaccgacttcaccgtgctgcccgtcgccctccacggcgacgcggccttcgcgggc
cagggcgtcgtcgccgagacgctgaacatgtcgcagctccgcggctaccgcaccggcggc
acggtccacgtcgtcatcaacaaccaggtcggcttcaccgccgcaccggagtcctcgcgc
tcctcgatgtacgcgacggacgtcgcccggatgatcgaagcgccgatcttccacgtcaac
ggcgacgaccccgaggcctgtgtccgggtcgcccggctggccttcgagttccgccagacg
ttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagggc
gacaacccgcagttcaccaacccgcagatggtcgcgctgatcgacaagaagcgttcggtg
cgcaagctgtacaccgagtccctgatcggccgcggcgacatcaccctcgaagaggcggag
caggcgctccaggacttccagggccagctggagaaggtgttcgcggaggtccgcgaggcc
accagccacccggcgccgaccctggtgccggacccgcaggccgaattcccggtcgccgtg
accaccgcggtgtcccaggaggtcatcaagcggatcgccgagtcccaggtcaacatcccg
gacaacatcaccgtccacccgcggctgctgccgcagctccagcgccgggccgcctccgtc
gaggacggcacgatcgactggggcatgggcgagacgctcgccatcggctccctgctgatg
gagggcaccccggtccggctctccggccaggacacccggcgcggcaccttcggccagcgc
cacgcggtcctggtcgaccaggagaccaacgaggactacaccccgctgctctacctgacc
gacgagcaggcccgctacaacgtctacgactccctgctcagcgagtacgcggcgatgggc
ttcgagtacggctactcgctggcccgccccgaatcgctggtcatgtgggaggcgcagttc
ggtgacttcgtcaacggcgcacagaccgtcgtcgacgagttcatctcctccgccgagcag
aagtggggccagacctccggcgtcaccctgctgctgccgcacggctacgagggccagggc
ccggaccactcgtccgcccgccccgagcgcttcctccagatgtgcgcgcagaacaatatg
acggtcgccatgccgacgctgccgtcgaactacttccatctgctgcggtggcaggtgcac
aacccgcaccacaagccgctgatcgtcttcaccccgaagtcgatgctccggctcaaggcc
gcgcagtcgaagacggaggagttcctcaacggcggcttccgcccggtcatcggtgacgag
tcggtcgacccgaacgcggtccgcaaggtggtcttcacctccggcaaggtctactacgac
ctcgacgcggagcggaagaagcgcggcatcacggacaccgcgatcctccgtcttgagcgg
ctgtacccgctgccgggtgcggagctgcaggccgagatcgccaagttcccgaacgccgag
aagtacatctgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctg
aacctgatcgaccacctggacctggcggtcggcgcggacgtgccgcacggcgagcgcctg
cgccgcatctcgcggccgcacggctcgtcgcccgcggtgggctcggcgaagcggcaccag
gcggagcagacgcagctggtggcggacgtcttcgacgcgtag

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