KEGG   Streptomonospora litoralis: EKD16_04440
Entry
EKD16_04440       CDS       T05863                                 
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
strr  Streptomonospora litoralis
Pathway
strr00020  Citrate cycle (TCA cycle)
strr00630  Glyoxylate and dicarboxylate metabolism
strr00785  Lipoic acid metabolism
strr01100  Metabolic pathways
strr01110  Biosynthesis of secondary metabolites
strr01120  Microbial metabolism in diverse environments
strr01200  Carbon metabolism
strr01210  2-Oxocarboxylic acid metabolism
Module
strr_M00009  Citrate cycle (TCA cycle, Krebs cycle)
strr_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:strr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    EKD16_04440 (kgd)
   00630 Glyoxylate and dicarboxylate metabolism
    EKD16_04440 (kgd)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    EKD16_04440 (kgd)
Enzymes [BR:strr01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     EKD16_04440 (kgd)
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     EKD16_04440 (kgd)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     EKD16_04440 (kgd)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     EKD16_04440 (kgd)
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: QBI52696
UniProt: A0A4P6PWT9
LinkDB
Position
complement(992216..995908)
AA seq 1230 aa
MSSEASQPLTDFGPNEWLVEELYQKYLNDPNSVDKAWWNFFADYKSGVPQANGSSKGASA
TSTQAAPSAGETTKGEKSTEPESAAPASGNGKKKAGSESDAEAEKPADESLKVNEERLRG
APARTAANMESSLALPTATSVRAVPVKLLFDNRIVINNHLRRGRGGKVSFTHIIGYAMVK
ALESMPEMNHSYTEVDGKPGVAKPEHVNFGLAIDLQKSDGSRQLVVPSIKSAETMDFKEF
WNGYEDLIRKARNNKLGVPDFQGTTISLTNPGGIGTVHSVPRLMPGQGTILGVGAMEYPA
EFQGAAPETLNNLAVSKVMTLTSTYDHRIIQGAQSGEFLRRIHQLLLGEDGFYDEIFRSL
RLPYEPVRWTQDISAAENQLDKTSRVQELIHAYRVRGHLMADTDPLEYHQRRHPDLDILE
HGLTLWDLEREFPTGGFGGKQVMKLRDVLGVLRDTYCRTVGIEYMHIQDPEEREWIQSHV
EREHEKVDRDEQLHILRRLNNAEAFETFLQTKYVGQKRFSLEGGESLIPLLDGVISRAAK
ADLDEVVIGMAHRGRLNVLANIAGKSYGQIFGEFEGNLDPRSAHGSGDVKYHLGTEGTFE
TPDGDKIAISLAANPSHLETVNPVAEGIVRAKQDVLDKGPHGFTVVPLLVHGDAAFAGQG
VVAETLNLSQLRGYRTGGTVHVIVNNQVGFTTSPADSRSSVYATDVARMVQAPIFHVNGD
DPEAVVRVAQLAYDYRQQFNKDVVIDLVCYRRRGHNETDNPAFTQPLMYDVIDAKRSTRK
LYTEALIGRGDISMEEAEQALRDYQEQLERAFTETREAGRKPVEPGAVIKPEVFDEGRID
HGSVETAISGEIVKQVVDTQVTLPEGFTPHPRLKPQLQRRAQMVEDDALDWATGEMLAFG
SLLTEEHPVRLVGQDTRRGTFGQRHSILVDRYTGKVHTPLKTFDKGTSKFYVHDSLLSEY
AALGFEYGYSVVRPDALVAWEAQFGDFVNGAQTIIDEYISASEQKWGQRSSVVLLLPHGY
EGQGPDHSSARIERFLQLCAQENMTVALPTTPANYFHLLRWQVKSQYRRPLVVITTKVML
RMKAATSTVADFTSGAFQPVIPDPSGPDPKKVRRVVLCSGKVYYELDAARQRTGDTSTAL
VRVERLYPLPTEEIRQLLAGYPNAGEVLWVQEEPANMGPWPFVALVFSEQLDRPFTRVSR
PASSAPAAGSGKRHEVEQQALINTVFPPAD
NT seq 3693 nt   +upstreamnt  +downstreamnt
gtgtcgtctgaggcgtctcaacccctgacagatttcggcccgaacgagtggttggtcgag
gagctttaccagaagtacctcaacgacccgaactcggttgacaaggcatggtggaacttc
ttcgccgactacaagtccggcgttccccaggccaacggttcgagcaagggtgcatcggcc
acgagcacccaggccgctccgagtgccggggaaaccaccaagggcgagaagtccaccgag
cccgagtccgcggcgcccgcctcgggcaacgggaagaagaaggccggatccgagtcggac
gccgaggccgagaagcccgccgacgaatccctcaaggtcaacgaggagcggctgcgcggc
gcacccgcgcgcacggccgcgaacatggagtccagcctggcgctgcccaccgccacgagc
gtgcgcgcggtgccggtcaagctgctgttcgacaaccgcatcgtgatcaacaaccacctg
cggcgcgggcgcggcggcaaggtgtccttcacccacatcatcggctacgccatggtgaag
gccctggagtccatgccggagatgaaccactcctacaccgaggtcgacggcaagccggga
gtggccaagcccgagcacgtcaacttcgggctggccatcgacctgcagaagtccgacggg
tcgcggcagctggtggtgcccagcatcaagtccgccgagacgatggacttcaaggagttc
tggaacggctacgaggacctgatccgcaaggcccgcaacaacaagctgggcgtgccggac
ttccagggcaccaccatcagcctcaccaaccccggcggcatcggcacggtgcactcggtg
ccccgcctcatgcccggccagggcaccatcctgggcgtgggcgccatggagtacccggcc
gagttccagggggccgcgcccgagaccctgaacaacctcgcggtcagcaaggtcatgacg
ctgacgtcgacctacgaccaccgcatcatccagggcgcccagtccggcgagttcctgcgc
cggatccaccagctgctgctgggcgaggacggcttctacgacgagatcttccgctcgctg
cggctgccttacgagccggtgcgctggacccaggacatctcggccgccgagaaccagctc
gacaagaccagccgcgtccaggagctgatccacgcctaccgggtccgcggccacctgatg
gccgacaccgacccgctggagtaccaccagcgccgccaccccgacctggacatcctcgaa
cacggcctgacgctgtgggacctggaacgcgagttccccaccggcggcttcggcggcaag
caggtcatgaagctgcgcgacgtgctcggcgtgctgcgcgacacctactgccgcacggtc
ggcatcgagtacatgcacatccaggatcccgaggaacgcgagtggatccagtcgcatgtc
gagcgcgagcacgagaaggtcgaccgcgacgagcagctgcacatcctgcgccggctgaac
aacgccgaggcgttcgagaccttcctgcagacgaagtacgtcggacagaagcggttctcc
ctcgaaggcggcgagtcgctgatcccgctgctggacggggtgatctcgcgcgccgcgaag
gccgatctggacgaggtcgtcatcggtatggcccaccgcggccggctgaacgtactcgcc
aacatcgccggcaagtcctacgggcagatcttcggcgagttcgagggcaacctcgacccg
cgcagcgcgcacggctccggtgacgtcaagtaccacctcggcaccgagggcaccttcgag
acccccgacggcgacaagatcgcgatctccctggcggcgaacccgagccacctggagacc
gtgaacccggtcgccgagggcatcgtccgcgccaagcaggacgtgctggacaagggcccg
cacgggttcaccgtcgtgccgctgctggtgcacggcgacgccgcgttcgccggccagggc
gtcgtcgccgagaccctgaacctgtcgcagctgcgcggctaccgcaccggcggcacggtg
cacgtcatcgtcaacaaccaggtcgggttcaccacctcgccggccgacagccgctccagc
gtctacgctaccgacgtggcgcggatggtgcaggcgccgatcttccacgtcaacggtgac
gaccccgaggcggtcgtgcgggtcgcccagctggcctatgactaccggcagcagttcaac
aaggacgtcgtcatcgacctggtctgctaccggcgccgcggccacaacgagaccgacaac
ccggccttcacccagccgctgatgtacgacgtgatcgacgccaagcgctccacgcgcaag
ctctacaccgaggcgctgatcggacgcggcgacatcagcatggaagaggccgagcaggcg
ctgcgcgactaccaggagcagctggaacgggccttcaccgagacccgcgaggcgggccgc
aagccggtcgagccgggcgcggtgatcaagccggaggtcttcgacgagggccgcatcgac
cacggctcggtggagaccgcgatctccggcgagatcgtcaagcaggtggtcgacacccag
gtgaccctgccggagggcttcaccccgcacccgcggttgaagccgcagctgcagcgccgc
gcccagatggtcgaggacgacgcgctggactgggcgaccggcgagatgctggcgttcggc
tcgctgctgaccgaggagcacccggtgcggctggtgggccaggacacccggcgcggcaca
ttcggtcagcggcactcgatcctggtcgaccgctacaccggcaaggtgcacacgccgctg
aagaccttcgacaagggcacctcgaagttctacgtgcacgactccctgctcagcgagtac
gcggcgctgggcttcgagtacggctactcggtggtgcgcccggacgcactggtggcctgg
gaggcccagttcggcgacttcgtcaacggcgcccagaccatcatcgacgagtacatcagc
gccagcgagcagaagtggggccagcgctccagcgtcgtgctgctgctgccgcacggctac
gagggccagggccccgaccactcctcggcgcgcatcgagcggttcctgcagctgtgcgcg
caggagaacatgaccgtggcgctgcccaccaccccggcgaactacttccacctgctgcgc
tggcaggtcaagtcgcagtaccgccggccgctggtggtcatcacgaccaaggtgatgctg
cggatgaaggccgcgacctcgacggtcgccgacttcacctcgggcgcgttccagccggtc
atcccggacccctcgggtcccgacccgaagaaggtccggcgcgtggtgctgtgctcgggc
aaggtctactacgagctggacgccgcgcggcagcgcaccggcgacaccagtacggcgctg
gtccgggtcgagcggctctacccgctgccgaccgaggagatccgccagctgctggcgggc
taccccaacgccggcgaggtgctgtgggtgcaggaggagccggcgaacatgggcccgtgg
ccgttcgtggcgctggtgttctccgagcagctcgaccgccccttcacgcgggtttcgcgt
ccggcgagctccgcccccgcggcgggctcgggcaagcggcacgaggtcgagcagcaggcg
ctcatcaacaccgtcttcccgccggccgactag

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