KEGG   Streptomyces sp. CNQ-509: AA958_23935
Entry
AA958_23935       CDS       T03968                                 
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
strc  Streptomyces sp. CNQ-509
Pathway
strc00020  Citrate cycle (TCA cycle)
strc00630  Glyoxylate and dicarboxylate metabolism
strc00785  Lipoic acid metabolism
strc01100  Metabolic pathways
strc01110  Biosynthesis of secondary metabolites
strc01120  Microbial metabolism in diverse environments
strc01200  Carbon metabolism
strc01210  2-Oxocarboxylic acid metabolism
Module
strc_M00009  Citrate cycle (TCA cycle, Krebs cycle)
strc_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:strc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    AA958_23935 (kgd)
   00630 Glyoxylate and dicarboxylate metabolism
    AA958_23935 (kgd)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    AA958_23935 (kgd)
Enzymes [BR:strc01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     AA958_23935 (kgd)
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     AA958_23935 (kgd)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     AA958_23935 (kgd)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     AA958_23935 (kgd)
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh Transket_pyr OxoGdeHyase_C 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: AKH84753
UniProt: A0A0F7NB74
LinkDB
Position
complement(5517556..5521365)
AA seq 1269 aa
MSSQSPKSSSSSVRTEEPSQGRDPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADY
KPGTAGGNQGAATQTAQPPPAAPPAPAQAAPAAHAAPAQAPAAPPQQAPAPAAPPAVDGR
PVARPPARPAAKPAKPATPAPAAAPEGPELVTLRGPAAAVAKNMNASLELPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQAMKLMPSMNHSFAEKDGKPTLVKPE
HVNLGLAIDLVKPNGDRQLVVAAIRKAETLNFFEFWQAYEDIVRRARSNKLTMDDFTGVT
CSLTNPGGIGTVHSVPRLMPGQSMILGVGAMDYPAEFQGTSQDTLNKLGVSKVMTLTSTY
DHRVIQGAASGEFLRIMHQLLLGENDFYDEVFKSLRIPYEPVRWLRDIDASHDDDVTKAA
RVFDLIHSYRVRGHVMADTDPLEYKQRKHPDLDVTEHGLTLWDLEREFAVGGFAGKSMMK
LRDILGVLRDSYCRTTGIEYMHIQDPKERKWIQERVERPHDTPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVIDAAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGTEGTFTGLDGEQIKVSLTANPSHLEAVDPV
LEGVVRAKQDIIGKGGTDFTVLPLALHGDAAFAGQGVVAETLNMSQLRGYRCGGTVHVVI
NNQVGFTAPPESARSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEYRQAFNKDVV
IDLICYRRRGHNEGDNPQFTNPQMVELIDKKRSVRKLYTESLIGRGDITMEEAEQALQDF
QGQLEKVFTEVRDATETPAPAEVPPHALPGFPVAVETAVSEEVVKRIADSQVSLPDQVSV
HPRLLPQLQRRVAMVEDNTIDWGMGETLAFGSLLMEGTPVRLAGQDSRRGTFGQRHAVLV
DQKTGEDYTPLNYLAPDQARYNVYDSLLSEYAAMGFEYGYSLARPDSLVLWEAQFGDFVN
GAQTVVDEFISSAEQKWGQSSGVVLLLPHGYEGQGPDHSSARIERFLQLSAQNNMTVAMP
TLPSSYFHLLRWQVHNPHHKPLVVFTPKSMLRMKAAASRTDEFTSGGFRPVIGDDSVEPA
AVRKVVFCSGKVYYDLDAERQKRGAQDTAIVRLERLYPLPGTEIQAELARYSGASTFVWA
QEEPANQGAWPFIALNLVDHLDLIIGSGPVPNADRLRRVSRPSSSSPAVGSAKRHQAEHA
QLMAEVFDL
NT seq 3810 nt   +upstreamnt  +downstreamnt
gtgtcgtcacagtcccctaagagcagctcgtcgagcgtccgtaccgaagagcccagccag
ggccgggaccctgctgccgccttcggtcccaacgagtggctcgtcgacgagatctaccag
cagtacctccaggaccccaactcggtggaccgggcctggtgggacttcttcgccgactac
aagccgggcaccgccggcgggaaccagggggcggcgacgcagacggcgcagcccccgccc
gccgcacccccggcccccgcccaggcggcccccgcggcccatgcggctccggcccaggcc
cccgccgcgccgccgcagcaggcccccgcgcccgccgcgccgccggccgtcgacggccgg
cccgtggcccggccgccggccaggcccgcggccaagccggcgaagcccgccaccccggcg
cccgccgccgcacccgagggccccgagctggtcaccctccggggccccgccgccgccgtc
gccaagaacatgaacgcctccctggagctgccgacggccacctcggtccgcgcggtcccg
gtgaagctcctcttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcccgcggc
gggaaggtctccttcacgcacctcatcgggtacgcgatggtccaggcgatgaagctgatg
ccgtcgatgaaccactccttcgcggagaaggacggcaagcccaccctggtcaagcccgag
cacgtcaacctcggcctggccatcgacctggtgaagcccaacggcgaccgccagctcgtc
gtcgcggccatcaggaaggccgagacgctcaacttcttcgagttctggcaggcgtacgag
gacatcgtccgccgcgcccggtccaacaagctcaccatggacgacttcaccggggtgacg
tgctcgctcaccaaccccggcggcatcggcaccgtgcactccgtgccccggctgatgccc
ggccagtccatgatcctcggcgtcggcgcgatggactaccccgccgagttccagggcacc
tcccaggacacgctgaacaagctgggcgtctccaaggtcatgacgctcacctcgacgtac
gaccaccgcgtcatccagggcgccgcctccggcgagttcctgcggatcatgcaccagttg
ctgctgggcgagaacgacttctacgacgaggtcttcaagtccctgcgcatcccgtacgag
ccggtgcgctggctccgcgacatcgacgccagccacgacgacgacgtcaccaaggccgcc
cgggtcttcgacctgatccactcctaccgggtccgcggccacgtcatggccgacaccgac
ccgctggagtacaagcagcgcaagcaccccgacctcgacgtcaccgagcacggcctgacg
ctctgggacctggagcgggagttcgccgtcggcggcttcgccggcaagtcgatgatgaag
ctgcgcgacatcctcggcgtactgcgggactcgtactgccgcaccaccggcatcgagtac
atgcacatccaggatccgaaggagcgcaagtggatccaggagcgcgtggagcgcccgcat
gacaccccggagcgcgaggagcaactgcgcatcctgcgccggctgaacgccgcggaggcg
ttcgagacgttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggc
gagtccgtcatcccgctgctggacgcggtcatcgacgccgccgccgagtcccgcctcgac
gaggtcgtcatcggcatggcgcaccgcggccggctcaacgtgctggcgaacatcgtcggc
aagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtgaagtaccacctgggcacggagggcacgttcaccggcctggacggc
gagcagatcaaggtctcgctcaccgccaacccgtcccacctggaggccgtcgacccggtc
ctggagggcgtggtccgcgccaagcaggacatcatcggcaagggcggcaccgacttcacc
gtgctgcccttggcgctccacggcgacgccgcgttcgccggccagggcgtggtggccgag
acgctcaacatgtcgcagttgcgcggctaccgctgcggcggcacggtgcacgtcgtcatc
aacaaccaggtcggcttcaccgccccgccggagtccgcgcgttcctcgatgtacgccacg
gacgtggcccgcatgatcgaggcgccgatcttccacgtcaacggcgacgaccccgaggcc
gtcgtgcgcgtcgcgcggctggccttcgagtaccgccaggcgttcaacaaggacgtggtc
atcgacctcatctgctaccgccgccgcgggcacaacgagggcgacaacccgcagttcacc
aacccgcagatggtcgagctgatcgacaagaagcgctcggtgcgcaagctctacaccgag
tcgctcatcggccgcggcgacatcaccatggaagaggccgagcaggcgctgcaggacttc
cagggccagttggagaaggtcttcaccgaggtacgggacgccaccgagacgcccgcgccg
gccgaggtgccgccgcacgcgctgcccggcttcccggtcgccgtggagacggccgtctcc
gaggaggtcgtcaagcggatcgccgactcccaggtcagcctccccgaccaggtgtcggtg
cacccgcggctgctgccgcagttgcagcgccgggtggcgatggtcgaggacaacacgatc
gactggggcatgggcgagacgctggcgttcggctcgctgctgatggagggcaccccggtc
cggctcgccggccaggactcccgccgcggcacgttcggccagcggcacgcggtgctcgtc
gaccagaagaccggcgaggactacaccccgctcaactacctcgcccccgaccaggcccgc
tacaacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctac
tcgctggcccgcccggactccctggtgctctgggaggcccagttcggcgacttcgtcaac
ggcgcgcagaccgtcgtcgacgagttcatctcctccgccgagcagaagtggggccagtcc
tccggcgtcgtgctgctgctgccgcacggctacgagggccagggcccggaccactcctcg
gcccgtatcgagcggttcctgcagctctccgcgcagaacaacatgaccgtcgcgatgccc
accctgccctcaagctacttccacctgctgcgctggcaggtccacaacccgcaccacaag
ccgctggtggtcttcaccccgaagtccatgctgcggatgaaggcggcggcgtcgcggacg
gacgagttcacctccggcggcttccggccggtcatcggcgacgactcggtcgagccggcg
gcggtccgcaaggtcgtcttctgctccggcaaggtctactacgacctcgacgccgagcgg
cagaagcgcggcgcgcaggacaccgcgatcgtccggctggagcggctgtacccgctgccc
ggcacggagatccaggcggagctggcgcgctacagcggcgcttcgacgttcgtctgggcc
caggaggagccggccaaccagggcgcgtggccgttcatcgcgctcaacctggtcgaccac
ctggacctgatcatcggctccgggccggtgccgaacgccgaccggctgcgccgggtctcg
cgcccgtcgtcgtcgtcccccgcggtcggctcggccaagcgccaccaggcggagcacgcc
cagttgatggccgaggtcttcgacctctga

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