Streptomyces spinosirectus: LXH13_26820
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Entry
LXH13_26820 CDS
T08958
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00020
Citrate cycle (TCA cycle)
sspn00630
Glyoxylate and dicarboxylate metabolism
sspn00785
Lipoic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01120
Microbial metabolism in diverse environments
sspn01200
Carbon metabolism
sspn01210
2-Oxocarboxylic acid metabolism
Module
sspn_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sspn_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LXH13_26820
00630 Glyoxylate and dicarboxylate metabolism
LXH13_26820
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LXH13_26820
Enzymes [BR:
sspn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LXH13_26820
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LXH13_26820
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LXH13_26820
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LXH13_26820
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UIR20422
LinkDB
All DBs
Position
complement(5779527..5783324)
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AA seq
1265 aa
AA seq
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MSPQSPSNSSLSTDTDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAAPAPAGTAAAGAAGTTSPAAPAQAAPAPAAPAPAPAAAKPAAAAPAPAQPAAAAKA
PAPAPAKPAAKPAAKAEPATEPAAGPELVTLRGPAAAVAKNMNASLELPTATSVRAVPVK
LLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPDHV
NLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFSGVTVS
LTNPGGLGTVHSVPRLMPGQSVILGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDH
RVIQGAASGEFLRQVANLLLGENGFYDEIFEALRIPYEPVRWLRDIDASHDDDVTKAARV
FELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMKLR
DILGVLRDSYCRTIGIEFMHIQDPKQRKWIQDRVERPHSKPEREEQLRILRRLNAAEAFE
TFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGKS
YAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVDPVIE
GIVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINN
QVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVID
LICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQG
QLEKVFTEVREATSQPGTAPVSDPQAEFPVPVTTAISAEVVKRIAESQVNIPDHFHVHPR
LLPQLQRRAAMVEDGTIDWGMGETLAIGSLLLENTPVRLSGQDSRRGTFGQRHAVLIDRE
TGEDLTPLQYLSDDQARYNVYDSLLSEYAVMGFEYGYSLARPDALVMWEAQFGDFVNGAQ
SVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNNMTVAMPTLP
SNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTSGQFRPVIGDSSVDPAAVK
KVVFVAGKLYYDLEAERTKRGATDIAIVRVERLYPLPGAEIQAEIAKYPNVEKYLWAQEE
PANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLVR
EVFEA
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagtctctcgaccgacaccgaccaagcgggcaag
aaccccgcggccgcgttcggccccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccc
ggagcggccgccgctccggcgccggcgggtactgcggccgcgggggccgcaggcaccacc
tccccggccgcgcccgcgcaggccgcaccggctccggcggcgcccgcgcccgccccggct
gctgccaagcccgcggccgccgctccggcgcccgcgcagccggccgccgccgcgaaggcc
ccggctcccgccccggccaagcccgccgccaagccggccgccaaggccgagcccgcgacg
gagcccgccgccggccccgagctggtgaccctgcgcggtcccgccgccgccgtggcgaag
aacatgaacgcctcgctggagctgcccacggccacgtccgtgcgcgcggtcccggtgaag
ctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccggggcgggaag
atctccttcacgcacctgatcgggtacgcgatggtgcaggccatcaaggccatgccgtcg
atgaattactccttcgcggagaaggacggcaagccgaccctggtcaagccggaccacgtc
aacctcggtctggccatcgacctggtgaagcccaacggcgaccgccagctggtcgtcgcg
gccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatc
gtccgccgcgcccgcgacggcaagctgacgatggacgacttctccggcgtgacggtctcc
ctgaccaaccccggcggcctcggcaccgtccactcggtcccgcgtctgatgcccggccag
tcggtcatcctgggcgtcggctccatggactacccggcggagttccagggcaccagccag
gacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccac
cgggtcatccagggcgccgcctccggcgagttcctgcgccaggtggcgaacctgctgctg
ggcgagaacggcttctacgacgagatcttcgaggccctgcgcatcccctacgagccggtc
cgctggctcagggacatcgacgccagccacgacgacgacgtcaccaaggccgcccgggtc
ttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctg
gagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctgaccctgtgg
gacctggagcgcgagttcgccgtcggcggcttctccggcaagtccctgatgaagctgcgc
gacatcctcggcgtgctgcgcgactcgtactgccgcaccatcggcatcgagttcatgcac
atccaggaccccaagcagcgcaagtggatccaggaccgggtggagcgcccgcactccaag
ccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgcggaggctttcgag
accttcctgcagacgaagtacgtcggccagaagcgcttctccttggagggcggcgagtcc
gtcatcccgctccttgacgcggtcctcgacagcgcggcggagtcgcgcctggacgaggtg
gtcatcggcatggcccaccgcggccggctgaacgtcctcgcgaacatcgtcggcaagtcg
tacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctcc
ggcgacgtgaagtaccacctgggcgccgagggcaccttcacgggcctggacggcgagcag
atcaaggtctcgctggccgccaacccctcccacctggagacggtcgacccggtcatcgag
ggcatcgtccgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtcctg
ccggtcgccctgcacggtgacgcggccttcgcgggccagggcgtggtggccgagaccctg
aacatgtcgcagctgcgcggctaccgcacgggcggcacggtccacatcgtcatcaacaac
caggtcggcttcaccgccgccccggagtcctcgcgttcgtcgatgtacgcgaccgacgtg
gcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggccgtggtc
cgcgtcgcgcggctggccttcgagttccgccaggcgttcaacaaggacgtggtgatcgac
ctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccg
ctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctg
atcggtcgcggcgacatcaccctggaagaggccgagcaggccctgcaggactaccagggc
cagctggagaaggtcttcaccgaggtccgcgaggccacgtcccagccgggcaccgccccg
gtgtcggacccacaggccgagttcccggtcccggtgaccaccgcgatctccgcggaggtc
gtcaagcggatcgccgagtcccaggtcaacatccccgaccacttccacgtacacccgcgt
ctgctgccgcagctgcagcgccgggcggcgatggtggaggacggcacgatcgactggggc
atgggcgagaccctcgccatcggctcgctgctgctggagaacaccccggtgcggctgtcc
ggccaggactcccgccgcggcaccttcggccagcgtcacgcggtcctcatcgaccgtgag
acgggcgaggacctgaccccgctgcagtacctctccgacgaccaggcccgctacaacgtc
tacgactcgctgctctccgagtacgcggtcatgggcttcgagtacggctactcgctggcc
cgccccgacgccctcgtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcccag
tcggtggtcgacgagtacatctcggcggccgagcagaagtggggccagacctccggcgtc
acgctgctgctcccgcacggctacgagggccagggcccggaccactcctcggcccgcgtc
gagcgcttcctgcagctgtgcgcgcagaacaacatgacggtcgcgatgccgaccctgccg
tcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtg
gtcttcacgccgaagtcgatgctgcgcctgaaggccgccgcgtcgaagacggaggagttc
acgtcgggtcagttccgtccggtcatcggcgactcctcggtcgacccggccgcggtcaag
aaggtcgtcttcgtggcgggcaagctgtattacgacctggaggccgagcgcaccaagcgc
ggcgccacggacatcgcgatcgtccgtgtcgagcggctgtacccgctgccgggtgccgag
atccaggcggagatcgccaagtacccgaacgtcgagaagtacctgtgggcccaggaggag
ccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggacctg
gcggtcggcgcggacgtcccgcacggcgagcgcctgcgccgcatctcgcgtccgcacagc
tcgtccccggcggtcggttccgcgaagcggcaccaggccgagcaggagcagctggtgcgc
gaggtgttcgaggcctag
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