KEGG   Solea senegalensis (Senegalese sole): 122783447
Entry
122783447         CDS       T07721                                 
Symbol
mthfd1b
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
ssen  Solea senegalensis (Senegalese sole)
Pathway
ssen00670  One carbon pool by folate
ssen01100  Metabolic pathways
ssen01240  Biosynthesis of cofactors
ssen04981  Folate transport and metabolism
Module
ssen_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ssen00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    122783447 (mthfd1b)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    122783447 (mthfd1b)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssen04147]
    122783447 (mthfd1b)
Enzymes [BR:ssen01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     122783447 (mthfd1b)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     122783447 (mthfd1b)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     122783447 (mthfd1b)
Exosome [BR:ssen04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   122783447 (mthfd1b)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 122783447
NCBI-ProteinID: XP_043904188
LinkDB
Position
LG16:complement(16155713..16165318)
AA seq 896 aa
MRASSCQKESPATASLSAAAPSAPKMSAQIISGKEVSAQVRERLKKDVEQMKLQDPNFSP
GLVVLQVGDRDDSNLYINMKLKAATEIGINATHTRLPKTATEEEVLHKITEVNENSSVHG
LIVQLPLDSIHKINTEKVTNAVAPEKDVDGLTSINAGKLSRGDLGECFIPCTPNGCMELI
KQTGVSVAGKRAVVLGRSKIVGAPMHDLLLWNHATVTTCHSKTADLAGEVGKADILVVGI
GKAQMVKGDWIKKGAVVIDCGINHIPDETKASGKRVVGDVDYEAAKEQAGFITPVPGGVG
PMTVAMLMANTVLSAKRFLDGHQPGKWNISFTKLNLLKPVPSDIVISRSCVPKPIDHLAK
EVGLLSDEVELYGKTKAKVQLNIVKRLQAQPDGKYVVVTGITPTPLGEGKSTTTIGLVQA
LGAHMNMNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLV
AAAIDARMFHESTQSDKALYNRLVPLSGGERKFSPIQINRLKKLGIEKTDPSTLTEEEIT
RFARLDIEPSAVTWHRVLDTNDRFLRKITIGQSPTEKGYTREAQFDITVASEIMAVLALT
SSLEDMRQRLAKMVVATSRGGQPITTEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHA
GPFANIAHGNSSILADKIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVV
LVATVRALKMHGGGPTVTAGMPLPKEYVEENLELLEKGCSNMKKQIENAQHFGVPVVVAV
NGFKTDTEAELDLVCSMAKTAGAFDAVRCSHWAEGGAGAVALGQAVQRASAAPSNFKFLY
DLELPIADKIRIIAQKIYGADDIELLPDAQHKVELYTKQVSSLHFFLSVTLCSLFC
NT seq 2691 nt   +upstreamnt  +downstreamnt
atgcgagcgtcttcttgtcagaaggagtcaccagcaacagcatcacttagcgccgcagct
cccagtgctcctaagatgtccgctcaaatcataagtgggaaagaagtttcagcgcaggtg
agggagcgtctgaagaaggatgtggagcagatgaagcttcaggaccccaacttctctcca
ggtttagtggttttacaggttggagaccgcgatgattcaaatctgtacatcaacatgaag
ttgaaggcagcaacagagattggaataaatgccacacatacgagacttccaaagacggcc
accgaggaggaggttcttcacaaaatcacagaagtgaacgagaactcgtccgtccacggc
ctcatcgtgcagctgcctttagactcgatccacaaaatcaacacagagaaggtcaccaat
gccgtggccccagagaaggatgtagatgggctcaccagcataaatgcagggaaactgtct
cgtggggacttgggtgaatgcttcattccctgcacgccaaacggctgcatggagttaatc
aaacaaactggtgtgtctgtggcagggaagagagccgtggtcctcggccgcagtaagatc
gtgggcgcgccgatgcatgacctgctgctgtggaaccatgccacggtcaccacctgccac
tccaaaactgctgatcttgctggagaggtgggaaaagcagacatcctagttgtcggcatc
ggcaaagcacagatggtaaaaggagactggatcaagaagggagcggtggtcatcgactgt
ggcatcaaccacattccagatgagactaaagccagtgggaagcgggtagtgggtgatgtg
gactacgaagccgctaaggagcaggccggcttcatcactccagtgccgggcggtgttgga
cccatgactgtggccatgctgatggcgaacacagtgctgagtgcaaagcgcttcctggac
ggacatcaaccagggaagtggaacatttctttcaccaaactcaacctgctgaaacctgtg
ccgagtgacatcgtgatctctcgctcctgcgtgcccaagcccattgaccatctggcaaag
gaggtgggcctgctctctgatgaggtggaactctatggaaagacgaaggcaaaggtccag
ctgaacatcgtcaaacgcctgcaggctcagccagatggcaaatatgtagtggtcactggc
attacacccactcctcttggtgagggaaagagcaccaccaccatcggactggttcaggcc
ctgggagcccacatgaacatgaatgtgttcgcgtgtgtccgacagccttctcagggaccc
acctttggcatcaaaggtggtgctgcaggcggtggatattctcaagtcattccaatggaa
gagttcaaccttcatctcaccggtgacattcacgccatcacggccgccaacaacttggtg
gctgccgccatcgacgctcgcatgttccacgagtccacgcagtctgacaaggcactgtac
aaccgcttggtcccgctcagtggaggagagaggaagttctcccccatccagatcaacaga
ctgaaaaaactgggcatagagaagaccgatccttccactctcactgaggaagagatcacc
cgctttgctcgtctggacattgagccaagcgctgtcacctggcacagagtgttggatact
aatgatagattcctgagaaagatcactatcggccagtcgcctactgaaaaaggatacacg
agagaggcccaattcgacatcacggtggctagtgaaatcatggcggtgctggcactcacc
agcagcctggaggacatgcgtcagcgtctggccaaaatggtcgtggccaccagccgcggt
ggacagccaatcaccacagaagatctgggtgtgagtggtgccctaactgtgctcatgaaa
gatgcgataaagccaaacctgatgcagacgttggagggtactcctgtgtttgtccatgcc
ggcccctttgccaacattgcccatggcaactcctccatcttggctgataaaatagctttg
aagttggttggacccgaggggtttgtagtgaccgaggctggttttggcgccgatatcggc
atggagaaattttttaacatcaagtgccgctactcgggcctgaggccacatgtggtggtg
ttggtggcgactgtccgagccctgaagatgcacggcggaggaccaactgttactgctgga
atgccactgccaaaggaatatgtggaggagaaccttgagctcctggagaagggctgcagc
aacatgaagaagcagatcgagaatgcacagcactttggtgttcccgtggtggtagcagtc
aacggtttcaagacggacacagaggctgagctggacttggtctgcagcatggctaaaacc
gccggagcgttcgacgccgtgcgatgctcccactgggctgagggcggagccggggcagtg
gccctcggtcaggccgtccagagagcctctgcagcgcccagcaactttaagttcctctat
gatttggagttacctattgctgataagattagaataattgcccagaagatctacggagca
gatgacatcgagctcctgccagatgcccaacataaggtggagctctacaccaaacaggtc
agcagccttcatttctttctttcagtcactttgtgcagcttgttttgttag

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