Streptomyces pluripotens: LK06_022575
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Entry
LK06_022575 CDS
T04845
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00020
Citrate cycle (TCA cycle)
splu00630
Glyoxylate and dicarboxylate metabolism
splu00785
Lipoic acid metabolism
splu01100
Metabolic pathways
splu01110
Biosynthesis of secondary metabolites
splu01120
Microbial metabolism in diverse environments
splu01200
Carbon metabolism
splu01210
2-Oxocarboxylic acid metabolism
Module
splu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
splu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LK06_022575
00630 Glyoxylate and dicarboxylate metabolism
LK06_022575
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LK06_022575
Enzymes [BR:
splu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LK06_022575
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LK06_022575
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LK06_022575
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LK06_022575
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ARP72274
UniProt:
A0A221P2M8
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All DBs
Position
complement(5013382..5017170)
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AA seq
1262 aa
AA seq
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MSPQSPSNPSISTDDHAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPG
APATPTPAGTAAAGAAGTPVTASQAQPAPAPAAPAAPKPAVAAPSPAPAAKATPAPVKPA
QPAPAPAQPKPKAAPAVQGPEGPELVTLRGPAAAVVKNMDASLEMPTATSVRAVPVKLLF
DNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYGVKDGKPTLIKPPHVNLG
LAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVSLTN
PGGLGTVHSVPRLMPSQSVIMGVGSMDYPAEFQGTSQDTLNKLGVSKVMTLTSTYDHRVI
QGAASGEFLRQVANLLLGENGFYDDVFKALRIPYEPVRWLKDIDASHDDDVTKAARVFEL
IHSYRVRGHVMADTDPLEYSQRKHPDLDIVEHGLTLWDLEREFAVGGFSGKSMMKLRDIL
GVLRDSYCRTTGIEFMHIQDPRQRKWIQDRVERTHSKPEREEQLRILRRLNAAEAFETFL
QTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQ
IFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVA
RAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVG
FTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLIC
YRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLDEAEQALQDYQGQLE
KVFTEVREATSQPLSGSVPVPQDGFPVTVPTAVSSEVVKRIAESQVNVPDHITVHPRLQP
QLQRRASMVEDGTIDWGMGETLAVGSLLLEGTPVRLAGQDSQRGTFGQRHAVLIDRETGE
EYTPLQYLSDDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVV
DEFVTSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPSNY
FHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTNGQFRPVIGDDSVDPATVRKVV
FCAGKVYYDLEAERKKRGATDTAIIRIERLYPLPGAELQEEIKKYPNAEKYLWAQEEPAN
QGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLAREVF
EA
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaacccgagcatctccaccgacgaccacgccgggaagaac
cccgcggccgcgttcggtccgaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtcgaccgcgcctggtgggacttcttcgccgactacaagccgggg
gctcctgccaccccgactccggcgggtactgcggccgcgggggccgcaggaacccccgtc
acggcgtctcaggcgcagcccgcaccggcccccgcggccccggccgcacccaagcctgcc
gtggcggctccctcccccgccccggcggcgaaggccacccccgccccggtcaagccggcg
cagcccgcaccggcgcccgctcagccgaagcccaaggccgcccccgccgtccagggcccg
gaaggccccgagctggtcacgctgcgcggcccggccgccgccgtggtgaagaacatggac
gcctcactggagatgccgaccgccacctcggtgcgcgcggtcccggtgaagctgctgttc
gacaaccggatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctccttc
acgcacatcatcgggtatgcgatggtgcaggccatcaaggccatgccgtcgatgaactgg
tcctacggcgtcaaggacggcaagccgaccctgatcaagccgccgcacgtcaacctcggc
ctggccatcgacctggtcaagccgaacggtgaccgccagctcgtcgtggccgccatcaag
aaggccgagaccctgaacttcttcgagttctggcaggcctacgaggacatcgtccggcgc
gcccgcgacggcaagctgacgatggacgacttcaccggtgtcacggtctccctgaccaac
cccggtggcctgggcaccgtccactcggtcccgcgtctgatgcccagccagtccgtgatc
atgggcgtcggctccatggactacccggccgagttccagggcaccagccaggacaccctc
aacaagctcggtgtctccaaggtcatgacgctgacgtcgacctacgaccaccgggtcatc
cagggtgccgcctccggcgagttcctgcgccaggtcgcgaacctgctgctgggcgagaac
ggcttctacgacgacgtcttcaaggcgctgcgcatcccctacgagccggtccgttggctc
aaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcccgcgtcttcgagttg
atccactcctaccgggtccgcggccacgtcatggccgacactgacccgttggagtacagc
cagcgcaagcaccccgacctggacatcgtcgagcacggcctcaccctgtgggacctggag
cgcgagttcgcggtcggcggcttctccggcaagtcgatgatgaagctgcgcgacatcctc
ggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggac
cccaggcagcgcaagtggatccaggaccgcgtggagcgcacccactccaagccggagcgc
gaggagcagctgcgcatcctgcgccggctgaacgcggcggaagccttcgagaccttcctg
cagaccaagtacgtcggacagaagcgcttctcgctggagggcggcgagtccgtcatcccg
ctgctcgacgcggtgatcgactcggccgccgagtcccgtctggacgaggtcgtcatcggc
atggcccaccgcggccggctgaacgttctcgcgaacatcgtcggcaagtcctacgcgcag
atcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtg
aagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcagatcaaggtc
tcgctggtcgccaacccctcccacctggaggccgtcgacccggtcctggagggtgtcgcc
cgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctaccggtggcg
atccacggcgacgcggccttcgcgggccagggcgtggtggccgagaccctgaacatgtcg
cagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaaccaggtcggc
ttcaccgcggcccccgagtcctcgcgttcctccatgtacgccacggacgtggcccgcatg
atcgaggcgccgatcttccacgtcaacggcgacgaccccgaggccgtcgtacgcgtggcg
cggctcgccttcgagttccgccaggcgttcaacaaggacgtggtgatcgacctcatctgc
taccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccgctgatgtac
gacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctgatcggtcgt
ggcgacatcactctggacgaggccgagcaggcacttcaggactaccagggccagctggag
aaggtcttcacggaggtccgcgaggcaacctcgcagccgctctccggcagcgtgccggta
ccccaggacggcttcccggtgacggtcccgaccgcggtctcctcggaggtcgtcaagcgg
atcgccgagtcccaggtcaacgtgcccgaccacatcaccgtccacccgcgcctgcagccg
cagttgcagcgccgtgcatcgatggtcgaggacggcacgatcgactggggcatgggcgag
accctcgccgtcggctccctgctgctggagggcactccggtccgactggccggccaggac
tcccagcgtggcaccttcggccagcgccacgcggtgctgatcgaccgggagaccggcgag
gagtacaccccgctgcagtacctctccgacgaccaggcccgcctgaacgtctacaactcc
ctgctctccgagtacgcggcgatgggcttcgagtacggctactcgctggcccgccccgac
gcgctggtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcccagacggtcgtg
gacgaattcgtcacctcggccgagcagaagtggggccagacctccggcgtggtcctgctg
ctcccgcacggatacgagggccagggaccggaccactcgtccgcgcgccccgaacgcttc
ctccagctgtgcgcgcagaacaacatgacggtggcgatgcccacgctcccgtcgaactac
ttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtcgtcttcacc
ccgaagtcgatgctgcgtctgaaggccgctgcctcgaaggcggaggagttcacgaacggc
cagttccgcccggtcatcggcgacgattcggtcgacccggccacggtccgcaaggtcgtc
ttctgcgccggcaaggtctactacgacctggaggcggagcggaagaagcgcggcgccacc
gatacggcgatcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccaggag
gagatcaagaagtacccgaacgcggagaagtacctctgggcccaggaggagccggccaac
cagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggacctggcggtcggg
gcggacgtcccgcacggcgaacgcctgcgccggatctcccgcccgcactcctcgtccccg
gccgtgggctccgccaagcgccaccaggccgagcaggagcagctggcgcgtgaggtgttc
gaggcgtag
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