Streptomyces leeuwenhoekii: sle_24580
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Entry
sle_24580 CDS
T04414
Symbol
sle_24580
Name
(GenBank) 2-oxoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00020
Citrate cycle (TCA cycle)
sle00630
Glyoxylate and dicarboxylate metabolism
sle00785
Lipoic acid metabolism
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
sle01120
Microbial metabolism in diverse environments
sle01200
Carbon metabolism
sle01210
2-Oxocarboxylic acid metabolism
Module
sle_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sle_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
sle_24580 (sle_24580)
00630 Glyoxylate and dicarboxylate metabolism
sle_24580 (sle_24580)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
sle_24580 (sle_24580)
Enzymes [BR:
sle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
sle_24580 (sle_24580)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
sle_24580 (sle_24580)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
sle_24580 (sle_24580)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
sle_24580 (sle_24580)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CQR61919
UniProt:
A0A0F7VNZ9
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All DBs
Position
chromosome:2988398..2992198
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AA seq
1266 aa
AA seq
DB search
MSPQSPSNSSSPTTDTDRAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAAAQASSGAAATGAAETTSTARPAAQAPQAPAPAAQAPAPAAQAPAPAAPEKPAAAA
KPAAAAAKPAAAPQPKAAPAKAPAEGPELVTLRGPAAAVAKNMDASLEMPTATSVRAVPV
KLLFDNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYGLKDGKPTLIKPEH
VNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRAREGKLTMDDFTGVTV
SLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYD
HRVIQGAASGEFLRVVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAAR
VFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKL
RDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKPEREEQLRILRRLNAAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRGRLNVLANIVGK
SYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVL
EGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVIN
NQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVARLAFEFRQAFNKDVVI
DLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQ
GQLEKVFTEVREATSQPSAVEPSDPQAEFPVAVNTAVTTETVKRIAESQVNIPDHITVHP
RLLPQLQRRATMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDR
NTGEEYTPLQYLSEEQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNGA
QTVVDEFISSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTS
PSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDASVDAAAV
KKVVFCSGKVYYDLDAERKKRGVTDTAIIRIERLYPLPGTELQAEIAKYPNAEKYLWAQE
EPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLV
REVFEA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagctcccccacgaccgacaccgaccgggcgggc
aagaaccccgccgccgcgttcggtgccaacgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaactccgtggaccgagcctggtgggacttcttcgccgactacaag
ccgggggcggccgccgcccaggcttcgtcgggtgctgcggccacgggggccgcagagacc
accagcacggcccggcccgccgcccaggccccccaggccccggcgccggctgcccaggcc
ccggctccagccgcacaggccccggctccggccgccccggagaagcccgccgcggccgcc
aagcccgccgccgcggccgcgaagcccgcggccgcgccgcagcctaaggccgcgcccgcc
aaggcgcccgccgagggtcccgagctggtgaccctgcgcggtcccgcggcggccgtcgcc
aagaacatggacgcctcgctggagatgccgacggccacctcggtccgcgccgtcccggtg
aagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccgcggcggg
aagatctccttcacgcacatcatcgggtacgcgatggtgcaggccatcaaggccatgccg
tccatgaactggtcgtacggcctcaaggacggcaagccgaccctgatcaagccggagcac
gtcaacctcggtctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtcgtc
gcggcgatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggac
atcgtccgccgcgcccgcgagggcaagctcacgatggacgacttcaccggtgtgacggtc
tccctgaccaaccccggcggcctcggcaccgtccactccgtcccgcgcctgatgcccggc
cagtcggtgatcatgggcgtcggctcgatggactacccggccgagttccagggcaccagc
caggacacgctcaacaagctgggcatctccaaggtcatgaccctgacgtcgacctacgac
caccgggtcatccagggcgccgcctccggcgagttcctgcgcgtcgtcgccaacctgctg
ctcggcgagaacggcttctacgacgacatcttcgaggcgctgcgcatcccctacgagccg
gtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaaggccgcccgc
gtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccg
ctggagtaccagcagcgcaagcaccccgacctggacatcaccgagcacgggctcaccctg
tgggacctggagcgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaagctg
cgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatg
cacatccaggaccccaagcagcgcaagtggatccaggaccgcgtggagcgcccgcacgcc
aagcccgagcgcgaggagcagctccgcatcctgcgccggctgaacgcggcggaggcgttc
gagaccttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggcgag
tccgtcatcccgctgctggacgcggtgctggactcggcggccgagtcccgcctggacgag
gtcgtcgtcggcatggcccaccgcggccggctgaacgtgctcgccaacatcgtcggcaag
tcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggc
tccggcgacgtgaagtaccacctgggcgccgaaggcaccttcaccggcctggacggcgag
cagatcaaggtctccctggtcgcgaacccctcccacctggaggccgtcgacccggtcctg
gagggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtc
ctgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtggtggccgagacc
ctgaacatgtcgcagctccgcggctaccgcaccggcggcacggtccacatcgtcatcaac
aaccaggtcggcttcaccgcggccccggagtcctcgcgctcctccatgtacgccaccgac
gtggcgcgcatgatcgaggcgccgatcttccacgtcaacggcgacgacccggaggcgtgc
gtccgcgtggcgcggctggccttcgagttccgccaggcgttcaacaaggacgtggtgatc
gacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccag
ccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtcc
ctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcccttcaggactaccag
ggccagctcgagaaggtcttcaccgaggtccgcgaggccacctcgcagccctccgccgtg
gagccctccgacccgcaggccgagttcccggtcgccgtgaacaccgcggtgaccacggag
accgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcacggtccacccg
cgcctgctgccgcagctccagcgccgggcgacgatggtcgaggacggcacgatcgactgg
ggcatgggcgagaccctcgccttcggctccctgctgctggagggcgtcccggtccgcctg
gcgggtcaggactcccagcgcggcaccttcggccagcgccacgcggtcatcatcgaccgc
aacaccggcgaggagtacacgccgctgcagtacctctccgaggagcaggcgcggctgaac
gtgtacaactcgctgctgtcggagtacgcggcgatgggcttcgagtacggctactcgctg
gcccgcccggacgcgctggtgctgtgggaggcccagttcggcgacttcgtcaacggcgcg
cagacggtcgtggacgagttcatctcctccgcggagcagaagtggggccagacctccggc
gtcgtcctgctcctcccccacggctacgagggccagggcccggaccactcctcggcccgc
ccggagcgcttcctccagctctgcgcccagaacaacatgacggtcgccatgccgacctcg
ccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctg
gtcgtcttcaccccgaagtcgatgctgcgcctgaaggcggcggcctcgaaggcggaggag
ttcaccaccggccagttccgcccggtcatcggcgacgcctccgtcgacgcggccgcggtc
aagaaggtcgtcttctgctccggcaaggtctactacgacctcgacgccgagcggaagaag
cgcggtgtgacggacacggcgatcatccgcatcgagcgcctgtacccgctgccgggtacc
gagctccaggcggagatcgccaagtacccgaacgccgagaagtacctgtgggcccaggag
gagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggac
ctggccgtcggcgccgatgtcccgcacggtgagcgcctgcgccgcatctcgcgtccgcac
agctcgtccccggccgtcggttccgcgaagcggcaccaggccgagcaggagcagctcgtg
cgtgaggtgttcgaggcgtaa
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