Streptomyces kanamyceticus: CP970_14080
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Entry
CP970_14080 CDS
T06849
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ska
Streptomyces kanamyceticus
Pathway
ska00020
Citrate cycle (TCA cycle)
ska00630
Glyoxylate and dicarboxylate metabolism
ska00785
Lipoic acid metabolism
ska01100
Metabolic pathways
ska01110
Biosynthesis of secondary metabolites
ska01120
Microbial metabolism in diverse environments
ska01200
Carbon metabolism
ska01210
2-Oxocarboxylic acid metabolism
Module
ska_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ska_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ska00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP970_14080
00630 Glyoxylate and dicarboxylate metabolism
CP970_14080
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP970_14080
Enzymes [BR:
ska01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP970_14080
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP970_14080
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP970_14080
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP970_14080
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
QEU91863
UniProt:
A0A5J6GA09
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All DBs
Position
3469530..3473414
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AA seq
1294 aa
AA seq
DB search
MPAVHHLVKRKRAVTAVSSQSPSSSSISTDQDGQGKDPAAAFGPNEWLVDEIYQQYLQDP
NSVDRAWWDFFADYKPGVGASVAAAPAKPAGDAAAGAAPTTTPAAPAAPAKSAAPAAPAA
PAAPATSSSAAPKATPAAAKPAAASSAAGAPASKPAAAAAKAAEPAKPAEAQGPEYVTLR
GPSAAVAKNMNASIEVPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMV
QAIKTMPSMNYSFVEKDGKPTLVKPEHINFGLAIDLVKPNGDRQLVVAGIKKAETLNFFE
FWQAYEDIVRRARDGKLGMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGAMDYP
AEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGEGEFYDEIFKA
LRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDI
TEHGLTLWDLEREFAVGGFAGKSMMKLRDVLGVLRDSYCRTTGVEFMHIQDPKQRKWLQD
RIERQHATKPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDS
AAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNMDPKSMHGSGDVKYHLGAEG
TFTGLDGEQIKVSLAANPSHLETVDPIIEGIARAKQDVINKGGTDFTVLPVALHGDAAFA
GQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHV
NGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRS
VRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVREATAQPGEAEVSAPEAEFPVK
IDTAISREIVKRIAESQVNIPDRVTVHPRLLPQLQRRATMVEEGTIDWGMGETLAIGSLL
LEGTPVRLSGQDSRRGTFGQRHAVLIDRATGEDFTPLLYLSEDQARYNVYDSLLSEYAVM
GFEYGYSLARPEALVMWEAQFGDFVNGAQTVVDEYISAAEQKWNQHSGVTLLLPHGYEGQ
GPDHSSARIERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLK
AAASKTEEFTSGGFRPVIGDATVDPAAVRKVVFCAGKLYYDLEAERTKRGATDTAIIRIE
RLYPLPGAELQAEIAKFPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPHGER
LRRISRPHGSSPAVGSKKRHEQEQEQLVREVFEA
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
attcccgctgtccatcaccttgtgaagcggaagagggcggttaccgccgtgtcgtcacag
tcccccagtagttcgagcatctcgaccgaccaagacggtcagggcaaggaccctgctgct
gccttcggtcccaatgagtggctcgtcgacgagatctatcagcagtacctccaggacccg
aattcggtcgaccgagcctggtgggacttctttgccgactacaagccaggggtgggcgct
tccgtagccgccgccccggcgaagccggcgggtgacgcggccgcgggggctgcgcccacc
accactcccgccgcgcccgctgccccggcgaagtccgcggctccggccgcgcccgccgcg
cccgcggctccggccacgagcagctcggccgctccgaaggccacgcccgccgcggcgaag
cccgcggcggcaagcagcgccgcaggcgcccccgcctccaagccggcggccgctgccgcc
aaggcagctgagccggccaagcccgccgaggcccaggggcccgagtacgtgacgctgcgt
ggcccttcggccgccgtcgcgaagaacatgaacgcctcgatcgaggtcccgacggcgacg
tcggtccgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctcaagcgcgcccgcggcgggaagatctccttcacgcacctcatcgggtacgcgatggtg
caggccatcaagaccatgccgtcgatgaactactccttcgtggagaaggacggcaagccg
accctggtcaagccggagcacatcaacttcggcctcgccatcgacctggtcaagcccaac
ggcgaccgccagctcgtggtcgcgggcatcaagaaggccgagaccctgaacttcttcgag
ttctggcaggcctacgaggacatcgtccggcgcgcccgcgacggcaagctcggcatggac
gacttcaccggcgtcacggtctcgctgaccaaccccggcggcctcggcaccgtccactcg
gtcccgcgcctgatgcccggacagtcggtcatcatgggcgtcggcgccatggactacccc
gcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatg
acgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctg
cgcatcgtcgcgaacctcctcctcggcgagggcgagttctacgacgagatcttcaaggct
ctccggatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgac
gacgtcacgaaggccgcccgcgtcttcgagctgatccactcctaccgcgtccgcggccac
gtcatggccgacacggacccgctggagtacaagcagcgcaagcaccccgacctggacatc
accgagcacggcctcaccctgtgggacctggagcgggagttcgcggtcggcggcttcgcc
ggcaagtcgatgatgaagctgcgcgacgtcctcggcgtcctgcgcgactcgtactgccgc
accaccggcgtcgagttcatgcacatccaggacccgaagcagcgcaagtggctgcaggac
cgcatcgagcgccagcacgccacgaagccggagcgcgaggagcagctgcgcatcctgcgc
cgcctgaactccgcggaggccttcgagaccttcctgcagacgaagtacgtcggccagaag
cgcttctccctggagggcggcgagtcggtcatcccgctgctcgacgccgtcatcgacagc
gccgccgagtcgcgtctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaac
gtcctcgccaacatcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggcaac
atggaccccaagtccatgcacggctccggcgacgtgaagtaccacctgggcgccgagggc
accttcaccggcctggacggcgagcagatcaaggtctccctcgcggcgaacccgtcccac
ctggagacggtcgacccgatcatcgagggcatcgcccgcgccaagcaggacgtcatcaac
aagggcggcacggacttcacggtcctgcccgtcgccctgcacggtgacgcggccttcgcg
ggccagggcgtggtcgccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggc
ggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcgtcg
cgctcctccatgtacgccacggacgtggcccgcatgatcgaggcgccgatcttccacgtg
aacggcgacgaccccgaggccgtcgtccgcgttgcccgtctggccttcgagttccgccag
gcgttcaacaaggacgtcgtcatcgacctcatctgctaccgccgccgcggtcacaacgag
tcggacaacccggcgttcacgcagccgctgatgtacgacctgatcgacaagaagcgctcg
gtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggcc
gagcaggcgctgcaggacttccagggccagctggagaaggtcttcacggaggtccgcgag
gccaccgcgcagcccggcgaggccgaggtgtccgcgccggaggccgagttcccggtcaag
atcgacaccgcgatctcccgtgagatcgtgaagcggatcgccgagtcccaggtcaacatc
cccgaccgggtcaccgtccacccgcgcctgctgccgcagctgcagcgccgcgcgacgatg
gtcgaagagggcacgatcgactggggcatgggcgagaccctcgccatcggctcgctgctc
ctggagggcaccccggtccgcctgtcgggccaggactcgcgccgcggcacgttcggtcag
cgccacgcggtcctcatcgaccgtgcgacgggcgaggacttcacgccgctcctgtacctc
tccgaggaccaggcgcgttacaacgtgtacgactcgctgctctccgagtacgcggtgatg
ggcttcgagtacggctactcgctggcccgccccgaggctctggtgatgtgggaggcgcag
ttcggcgacttcgtcaacggcgcgcagacggtggtggacgagtacatctcggccgccgag
cagaagtggaaccagcactccggcgtcacgctgctgctgccccacggctacgagggccag
ggcccggaccactcgtccgcccgcatcgagcggttcctccagctgtgcgcgcagaacaac
atgaccgtcgcgatgccgacgctcccttcgaactacttccacctcctgcggtggcaggtg
cacaacccgcaccacaagccgctggtcgtcttcaccccgaagtcgatgctgcgcctgaag
gccgccgcgtcgaagacggaggagttcaccagcggtggcttccgcccggtgatcggcgac
gcgacggtcgacccggccgcggtgcgcaaggtggtgttctgcgcgggcaagctctactac
gacctcgaggcggagcgcaccaagcgcggcgcgacggacacggccatcatccgcatcgag
cgcctgtacccgctgccgggtgccgagctccaggcggagatcgccaagttcccgaacgcc
gagaagtacctgtgggcgcaggaggagccggcgaaccagggcgcgtggcccttcatcgcc
ctcaacctcatcgaccacctggacctggcggtcggcgccgacatcccgcacggcgagcgc
ctgcgccgcatctcgcgcccgcacggctcgtcccccgcggtcggctcgaagaagcgtcac
gagcaggagcaggagcagctcgtacgcgaggtgttcgaggcctag
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