Streptomyces aurantiacus: GCM10017557_26170
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Entry
GCM10017557_26170 CDS
T07085
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgm
Streptomyces aurantiacus
Pathway
sgm00020
Citrate cycle (TCA cycle)
sgm00630
Glyoxylate and dicarboxylate metabolism
sgm00785
Lipoic acid metabolism
sgm01100
Metabolic pathways
sgm01110
Biosynthesis of secondary metabolites
sgm01120
Microbial metabolism in diverse environments
sgm01200
Carbon metabolism
sgm01210
2-Oxocarboxylic acid metabolism
Module
sgm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgm_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
GCM10017557_26170 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
GCM10017557_26170 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GCM10017557_26170 (kgd)
Enzymes [BR:
sgm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
GCM10017557_26170 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
GCM10017557_26170 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
GCM10017557_26170 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
GCM10017557_26170 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BCL27758
UniProt:
A0A7G1NX82
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All DBs
Position
3136532..3140383
Genome browser
AA seq
1283 aa
AA seq
DB search
MSPQSPSNSSSVSTEDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGVAASAPAGAAAAGAAGTTAPPKAAPAAPAAPAAPPAQAQAAPAPASVAPVKAAPAAQA
APAVAKPAAAAPAKPAAAGPAAAKAAPASQAAPAAEATASPAGPQYVTLRGPSAAVVKNM
NASVEVPTATSVRALPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMN
YSFTEKDGKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVR
RARDGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDT
LNKLGIAKVMTLTSTYDHRVIQGAASGEFLRIVANYLLGENGFYDEIFEALRIPYEPVRW
LKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDL
EREFAVGGFAGKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERPHSKPE
REEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVI
GMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGVFTGLDGEQIK
VSLAANPSHLEAVDPILEGVARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNM
SQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRV
ARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIG
RGDITLEEAEQALQDYQGQLEKVFTEVREAASAPSEAHVPDTKPEFPVAVTTAVSQEVVK
RIAESQVNIPERVTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGTPVRLSGQ
DSRRGTFGQRHAVLIDRATAEDFTPLQYLSEDQARYNCYDSLLSEYAAMGFEYGYSLARP
ESLVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPER
FLQMCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTT
GGFRPVIGDDSVDPAAVKKVVFTAGKVYYDLDGERKKRGITDTAVIRIERLYPLPGAELQ
AEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPAGSS
PAVGSAKRHQAEQEQLVHEVFDA
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcatcgagcgtctcgaccgaggaccaagccgggaag
aaccctgccgccgcgttcggtcccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcggcgtggccgcctcggctccggcaggtgccgcggccgcgggggccgcgggaaccacc
gccccaccgaaggcagctccggcggctccggccgcccctgccgcacccccggcccaggcg
caggccgcgccggccccggcttcggtcgctccggtcaaggcggccccggccgcccaggcc
gcacccgcggtcgccaagcccgcggctgccgcaccggcgaagcccgcggcggccgggccg
gccgccgccaaggccgcgcccgcgtcccaggccgccccggccgccgaggccaccgcgtcc
ccggccgggcctcagtacgtgacgctgcgcggcccgagcgccgcggtcgtgaagaacatg
aacgcctccgtcgaggtgcccacggccacgtccgtgcgcgcgctccccgtgaagctgctc
ttcgacaaccgcatcgtcatcaacaaccacctgaagcgtgcccggggcgggaagatctcc
ttcacccacctcatcggctacgcgatggtgcaggccatcaaggccatgccgtcgatgaac
tactccttcacggagaaggacggcaagccgaccctggtcaagccggagcacgtcaacttc
ggcctcgccatcgacctggtgaagcccaacggcgaccgccagctggtcgtcgcgggcatc
aagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatcgtccgc
cgggcccgtgacggcaagctgacgatggacgacttcaccggtgtcacggtctcgctgacc
aacccgggcggcctcggcaccgtccactcggtcccgcgtctgatgcccggacagtcggtc
atcatgggcgtcggctcgatggactacccggcggagttccagggcacctcccaggacacc
ctgaacaagctcggcatcgcgaaggtcatgacgctcacgtcgacctacgaccaccgggtc
atccagggcgccgcgtccggcgagttcctccgcatcgtcgcgaactacctcctcggtgag
aacggcttctacgacgagatcttcgaggccctgcgcattccgtacgagccggtccgctgg
ctcaaggacatcgacgcctcgcacgacgacgacgtcacgaaggccgcccgggtcttcgag
ctgatccactcctaccgcgtccgcggccacgtcatggccgacaccgacccgctggagtac
cgccagcgcaagcaccccgacctggacatcaccgagcacgggctcaccctgtgggacctg
gagcgcgagttcgcggtcggcggtttcgcgggcaagtccctgatgaagctccgcgacatc
ctcggtgtgctgcgcgactcgtactgccgcaccaccggcgtcgagttcatgcacatccag
gacccgaagcagcgcaagtggatccaggaccgcatcgagcgcccgcacagcaagccggag
cgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaagccttcgagaccttc
ctgcagacgaagtacgtcggccagaagcgcttctccctggagggcggcgagtccgtcatc
ccgctgctcgacgcggtgctcgactccgccgccgagtcgcgcctggacgaggtcgtcatc
ggcatggcccaccgcggccgcctgaacgtcctcgcgaacatcgtcggcaagtcgtacgcg
cagatcttccgggagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgac
gtcaagtaccacctgggcgccgagggtgtcttcaccggcctggacggcgagcagatcaag
gtctcgctggccgccaacccctcgcacctggaggcggtcgacccgatcctggagggcgtc
gcccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctccccgtc
gccctgcacggtgacgcggccttcgcgggccagggcgtggtggccgagaccctgaacatg
tcgcagctgcgcggctaccgcaccggcggcacggtccacgtggtcatcaacaaccaggtc
ggcttcaccgcggcgcccgagtcctcgcgttcgtccatgtacgcgaccgacgtggcccgc
atgatcgaggccccgatcttccacgtgaacggcgacgacccggaggccgtggtgcgcgtc
gcgcggctcgccttcgagttccgtcaggcgttcaacaaggacgtggtgatcgacctcatc
tgctaccgccgccgcggtcacaacgagtccgacaacccggcgttcacccagccgctgatg
tacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtcgctgatcggc
cggggcgacatcacgctggaagaggccgagcaggcgctccaggactaccagggccagctg
gagaaggtcttcacggaggtccgcgaggcggcgtccgcgccgtccgaggcccatgtcccg
gacacgaagcccgagttcccggtggcggtcaccacggccgtctcccaggaggtcgtcaag
cggatcgccgagtcccaggtcaacatccccgagcgggtcaccgtccacccgcgtctgctg
ccccagctgcagcgccgcgcggcgatggtcgaggacggcacgatcgactggggcatgggc
gagacgctcgcgatcggctccctgctcctggagggcaccccggtgcgcctctcgggccag
gactccaggcggggcacgttcggccagcgccacgcggtgctcatcgaccgggcgacggcc
gaggacttcaccccgctgcagtacctctcggaggaccaggcccgctacaactgctacgac
tcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcgcgtccc
gagtccctcgtgatgtgggaggcccagttcggcgacttcgtcaacggcgcccagacggtg
gtggacgagttcatctcgtcggcggagcagaagtggggccagacgtccggcgtcacgctg
ctcctcccgcacggctacgagggccagggcccggaccactcgtccgcgcgcccggagcgg
ttcctccagatgtgcgcgcagaacaacatgacggtcgccatgccgacgctcccgtcgaac
tacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtggtcttc
accccgaagtcgatgctccgcctgaaggcggcggcgtcgaaggcggaggagttcacgaca
ggcggcttccgtccggtcatcggtgacgactcggtcgacccggcggcggtgaagaaggtc
gtcttcacggcgggcaaggtctactacgacctcgacggtgagcgtaagaagcgcggcatc
acggacacggccgtcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccag
gcggagatcgccaagtacccgaacgccgagaaatacctgtgggcccaggaggagccggcg
aaccagggcgcgtggccgttcatcgcgctcaacctgatcgaccacctggacctggcggtc
ggcgcggacgtcccccacggggagcggctgcggcgcatctcgcgtccggcgggctcgtcc
ccggcggtgggctccgccaagcgccaccaggccgagcaggagcagctcgtccacgaggtg
ttcgacgcctga
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