Streptomyces formicae: KY5_5413c
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Entry
KY5_5413c CDS
T05416
Name
(GenBank) Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sfk
Streptomyces formicae
Pathway
sfk00020
Citrate cycle (TCA cycle)
sfk00630
Glyoxylate and dicarboxylate metabolism
sfk00785
Lipoic acid metabolism
sfk01100
Metabolic pathways
sfk01110
Biosynthesis of secondary metabolites
sfk01120
Microbial metabolism in diverse environments
sfk01200
Carbon metabolism
sfk01210
2-Oxocarboxylic acid metabolism
Module
sfk_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sfk_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sfk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
KY5_5413c
00630 Glyoxylate and dicarboxylate metabolism
KY5_5413c
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KY5_5413c
Enzymes [BR:
sfk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
KY5_5413c
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
KY5_5413c
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
KY5_5413c
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
KY5_5413c
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ATL30431
UniProt:
A0A291QFE9
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All DBs
Position
complement(6247880..6251665)
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AA seq
1261 aa
AA seq
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MSSQSPSSSSISTDQDGQGKDPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GVGASVAAAPAKPAGDAAAGAAPTTPAAPAKPAAKAAPAAPAAPAAPAAKPAAAAPAPAA
KPAAAKPAAKAEPAKEAPAGPEYVTLRGPSAAVAKNMNASIEVPTATSVRAVPVKLLFDN
RIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFVEKDGKPTLVKPEHINFGLA
IDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDFTGVTVSLTNPG
GLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQG
AASGEFLRIVANLLLGEQDFYDEIFKALRIPYEPVRWLKDIDASHDDDVTKAARVFELIH
SYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKLRDVLGV
LRDSYCRTTGVEFMHIQDPKQRRWLQDRIERQHATKPEREEQLRILRRLNSAEAFETFLQ
TKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQI
FREFEGNMDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVDPIIEGIVR
AKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGF
TAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICY
RRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEK
VFTEVREATAQPGEAEVPAPEAEFPVKIDTAISQEIVKRIAESQVNIPDRVTVHPRLLPQ
LQRRATMVEEGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQRHAVLIDRATGED
FTPLLYLSEDQARYNVYDSLLSEYAVMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVVD
EYISAAEQKWNQHSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSNYF
HLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTSGGFRPVIGDATVDPAAVRKVVF
CAGKLYYDLEAERTKRGATDTALIRIERLYPLPGAELQAEIAKFPNAEKYLWAQEEPANQ
GAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHGSSPAVGSKKRHEQEQEQLVREVFE
A
NT seq
3786 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtcacagtcccccagtagctcgagcatctcgaccgaccaagacggtcagggcaag
gaccctgctgctgccttcggtcccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtcgaccgagcctggtgggacttcttcgccgactacaagcca
ggggtgggcgcttccgtagccgccgccccggcgaagccggcgggtgacgcggccgcgggg
gccgcgcccaccactcccgccgccccggcgaagcccgcggccaaggccgcgcccgccgcc
cccgcggctccggcagcccccgccgcgaagcccgcggccgccgctccggcccccgcggcc
aagcccgccgccgcgaagcccgccgccaaggcggagcccgcgaaggaggccccggcaggg
cccgagtacgtgacgctgcgcggtccctcggccgctgtcgcgaagaacatgaacgcctcc
atcgaggtccccaccgccacgtcggtgcgcgcggtcccggtgaagctgctcttcgacaac
cgcatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctccttcacgcac
ctcatcgggtacgcgatggtgcaggccatcaaggccatgccgtcgatgaactactccttc
gtggagaaggacggcaagccgaccctggtcaagccggagcacatcaacttcggcctcgcc
atcgacctggtgaagcccaacggcgaccgccagctcgtggtcgcgggcatcaagaaggcc
gagaccctgaacttcttcgagttctggcaggcctacgaggacatcgtccggcgcgcccgc
gacggcaagctcggcatggacgacttcaccggcgtcacggtctcgctgaccaaccccggc
ggcctcggcaccgtccactcggtcccccgcctgatgcccggccagtcggtcatcatgggc
gtcggctcgatggactacccggcggagttccagggcacctcccaggacaccctgaacaag
ctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtcatccagggc
gccgcctccggcgagttcctgcgcatcgtcgcgaacctcctcctcggcgagcaggacttc
tacgacgagatcttcaaggcgctccggatcccctacgagccggtccgctggctcaaggac
atcgacgcctcgcacgacgacgacgtcacgaaggccgcccgcgtcttcgagctgatccac
tcctaccgggtgcgcggccacgtcatggccgacacggacccgctggagtacaagcagcgc
aagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctggagcgggag
ttcgcggtcggcggcttcgccggcaagtcgatgatgaagctgcgcgacgtcctcggcgtc
ctgcgcgactcgtactgccgcaccaccggcgtcgagttcatgcacatccaggacccgaag
cagcgcaggtggctccaggaccgcatcgagcgccagcacgccacgaagccggagcgcgag
gagcagctgcgcatcctgcgccggctgaactccgccgaggccttcgagaccttcctgcag
acgaagtacgtcggccagaagcgcttctccctggagggcggcgagtcggtcatcccgctg
ctcgacgccgtcatcgacagcgccgccgagtcgcgcctggacgaggtcgtcatcggcatg
gcccaccgcggccgcctgaacgtcctcgccaacatcgtcggcaagtcgtacgcccagatc
ttccgcgagttcgagggcaacatggaccccaagtccatgcacggctccggcgacgtgaag
taccacctgggcgccgagggcaccttcaccggcctcgacggcgagcagatcaaggtctcg
ctcgcggcgaacccgtcccacctggagacggtcgacccgatcatcgagggcatcgtccgc
gccaagcaggacatcatcaacaagggcggcacggacttcacggtcctgcccgtcgccctg
cacggtgacgcggccttcgcgggccagggtgtggtcgccgagacgctgaacatgtcgcag
ctgcgcggttaccgcacgggcggcacggtccacatcgtcatcaacaaccaggtcggcttc
accgccgccccggagtcgtcgcgctcctccatgtacgccacggacgtggcccgcatgatc
gaggcgccgatcttccacgtgaacggcgacgaccccgaggccgtcgtccgcgtcgcccgc
ctcgccttcgagttccgccaggcgttcaacaaggatgtggtcatcgacctcatctgctac
cgccgccgcggtcacaacgagtcggacaacccggcgttcacgcagccgctgatgtacgac
ctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgcggc
gacatcaccctggaagaggccgagcaggcgctccaggacttccagggccagctggagaag
gtcttcacggaggtccgcgaggccaccgcgcagcccggcgaggccgaggtcccggcgccg
gaggccgagttccccgtcaagatcgacaccgcgatctcccaggagatcgtgaagcggatc
gccgagtcccaggtcaacatccccgaccgggtcaccgtccacccgcgcctgctgccgcag
ctgcagcgccgcgcgacgatggtcgaagagggcacgatcgactggggcatgggcgagacc
ctcgccatcggctcgctgctcctggagggcaccccggtccgcctgtcgggccaggactcg
cgccgcggcacgttcggtcagcgccacgcggtgctcatcgaccgcgcgacgggcgaggac
ttcacgccgcttctgtacctctccgaggaccaggcgcgctacaacgtctacgactcgctg
ctctccgagtacgcggtgatgggcttcgagtacggctactcgctggcccgccccgaggct
ctggtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcgcagacggtggtggac
gagtacatctcggccgccgagcagaagtggaaccagcactccggcgtcacgctgctgctg
ccccacggctacgagggccagggcccggaccactcgtccgcccgcatcgagcgcttcctc
cagctgtgcgcgcagaacaacatgaccgtcgcgatgccgacgctcccgtcgaactacttc
cacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtcgtcttcaccccg
aagtcgatgctgcgcctgaaggccgccgcgtcgaagacggaggagttcaccagcggtggc
ttccgcccggtgatcggcgacgcgacggtcgacccggccgcggtgcgcaaggtggtgttc
tgcgcgggcaagctctactacgacctggaggcggagcgcaccaagcgcggcgccacggac
acggccctcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccaggcggag
atcgccaagttcccgaacgccgagaagtacctgtgggcgcaggaggagccggcgaaccag
ggcgcgtggcccttcatcgccctcaacctcatcgaccacctggacctggcggtcggcgcc
gacatcccgcacggcgagcgcctgcgccgcatctcgcgcccgcacggctcgtcccccgcg
gtcggctcgaagaagcgtcacgagcaggagcaggagcagctcgtacgcgaggtgttcgag
gcctag
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