Streptomyces chromofuscus: IPT68_24365
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Entry
IPT68_24365 CDS
T07378
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
schf
Streptomyces chromofuscus
Pathway
schf00020
Citrate cycle (TCA cycle)
schf00630
Glyoxylate and dicarboxylate metabolism
schf00785
Lipoic acid metabolism
schf01100
Metabolic pathways
schf01110
Biosynthesis of secondary metabolites
schf01120
Microbial metabolism in diverse environments
schf01200
Carbon metabolism
schf01210
2-Oxocarboxylic acid metabolism
Module
schf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
schf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
schf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
IPT68_24365
00630 Glyoxylate and dicarboxylate metabolism
IPT68_24365
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IPT68_24365
Enzymes [BR:
schf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
IPT68_24365
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
IPT68_24365
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
IPT68_24365
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
IPT68_24365
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QOV42905
UniProt:
A0A7M2T4S3
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All DBs
Position
complement(5375584..5379417)
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AA seq
1277 aa
AA seq
DB search
MSPQSPSNASSISTDADQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAATPAPAGTAAAGAAETSPTLESTRAGGPPSTAPTPVQAAAAPAQAAPAAPAAPKPA
AAAPAQPKAPAPAPAPAAAKPQPKVKAAEPAAVAPEGPELITLRGPAAAVAKNMNASLEL
PTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWSFGEK
DGKPTLVKPPHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGK
LTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGAMDYPAEFQGTSQDTLNKLGI
SKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDA
SHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAV
GGFSGKSLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERPHAKPEREEQLR
ILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRG
RLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTAN
PSHLEAVDPVLEGVARAKQDIINKGGTDFTVLPIALHGDAAFAGQGVVAETLNMSQLRGY
RTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFE
FRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITL
EEAEQALQDYQGQLEKVFTEVREATSQPATVATPDTQAEFPVAVNTAVSTEIVKRIAESQ
VNIPDHITVHPRLLPQLQRRASMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGT
FGQRHAVIIDRSTGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLW
EAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCA
QNNMTVAMPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKADEFTTGGFRPV
IGDASVDPAAVRKVVFCAGKVYYDLEAERVKRGVTDTAIIRIERLYPLPGAELQAEIKKY
PNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSA
KRHQAEQEQLVREVFEA
NT seq
3834 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaacgcatcgagcatctcgaccgacgcagaccaagcgggc
aagaatcccgccgccgcgttcggaccgaacgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaattcggtcgaccgcgcctggtgggacttcttcgccgactacaag
cccggggcggctgccaccccggcgccggcgggtaccgcggccgcgggggccgcggagacc
tcccccacgctcgaatccactcgcgcggggggacccccatccacggctccgacgcccgtc
caggccgctgcggcgcccgcccaggcggccccggccgcccccgcggccccgaagcccgcc
gcggcagctcccgcgcagccgaaggctccggccccggctcccgcgccggccgccgccaag
ccgcagccgaaggttaaggccgccgagccggccgcggtggccccggagggccccgagctg
atcacgctgcgcggcccggccgccgccgtcgcgaagaacatgaacgcctcgttggagctg
ccgaccgccacctcggtccgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtc
atcaacaaccacctcaagcgcgcccggggcgggaagatctccttcacgcacctgatcggc
tacgcgatggtgcaggccatcaaggccatgccgtcgatgaactggtcgttcggcgagaag
gacggcaagccgaccctcgtcaagccgccgcacgtcaacctcggtctcgccatcgacctg
gtcaagcccaacggcgaccgccagctggtcgtcgcggcgatcaagaaggccgagacgctg
aacttcttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaag
ctgacgatggacgacttcaccggcgtcaccgtctccctcaccaaccccggcggcctcggc
accgtccactcggtcccgcgcctgatgcccggccagtcggtgatcatgggcgtcggcgcc
atggactacccggcggagttccagggcacctcccaggacaccctgaacaagctcggcatc
tcgaaggtcatgacgctcacgtcgacctacgaccaccgggtgatccagggcgccgcgtcc
ggcgagttcctgcgccaggtcgcgaacctgctcctcggtgagaacggcttctacgacgac
atcttcgaggcgctgcgcatcccctacgagccagtccgctggctcaaggacatcgacgcc
agccacgacgacgacgtcacgaaggccgcccgggtcttcgagctgatccactcctaccgg
gtccgcggccacgtcatggccgacaccgacccgctggagtaccgccagcgcaagcacccc
gacctcgacatcaccgagcacggcctcaccctgtgggacctggagcgcgagttcgcggtc
ggcggcttctccggcaagtccctgatgaagctgcgcgacatcctcggcgtgctgcgtgac
tcgtactgccgcaccaccggcatcgagttcatgcacatccaggaccccaagcagcgcaag
tggatccaggaccgcatcgagcgcccgcacgccaagccggagcgcgaggagcagctgcgg
atcctgcgccggctgaacgcggcggaggccttcgagaccttcctgcagacgaagtacgtc
ggccagaagcgcttctccctggagggcggcgagtccgtcatcccgctgctcgacgcggtg
ctggactcggccgccgagtcccgcctcgacgaggtcgtcatcggcatggcccaccgcggc
cggctgaacgtcctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttc
gagggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggc
gccgagggcaccttcaccggcctggacggcgagcagatcaaggtctcgctcaccgccaac
ccctcccacctggaggcggtcgacccggtcctggagggcgtagcccgcgccaagcaggac
atcatcaacaagggcggcacggacttcaccgtcctgccgatcgccctgcacggcgacgcg
gccttcgcgggccagggtgtcgtggccgagacgctgaacatgtcgcagctgcgcggctac
cgcaccggcggcaccgtccacgtcgtcatcaacaaccaggtcggcttcaccgcggccccc
gagtcctcgcgttcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatc
ttccatgtgaacggcgacgaccccgaggccgtcgtccgcgtcgcgcggctcgccttcgag
ttccgccaggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggt
cacaacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaag
aagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctg
gaagaggccgagcaggcgctgcaggactaccagggccagctggagaaggtcttcaccgag
gtccgcgaggccacctcgcagccggcgacggtggcgacgccggacacgcaggccgagttc
ccggtcgccgtgaacaccgccgtctccacggagatcgtcaagcggatcgccgagtcccag
gtcaacatccccgaccacatcaccgtccacccgcgtctgctgccgcagctgcagcgccgg
gcgtcgatggtcgaggacggcacgatcgactggggcatgggcgagaccctcgccttcggc
tcgctgctcctggagggcgtcccggtccggctcgcgggccaggactcccagcgcggcacc
ttcggccagcggcacgcggtcatcatcgaccgcagcaccggcgaggagtacacgccgctg
cagtacctgtcggaggaccaggcacgcctgaacgtctacaactccctgctgtccgagtac
gcggcgatgggcttcgagtacggctactcgctggcccgcccggacgcgctcgtgctgtgg
gaggctcagttcggtgacttcgtcaacggtgcgcagacggtcgtggacgagttcatctcg
tcggcggagcagaagtggggccagacgtccggcgtcaccctgctcctcccccacggctac
gagggccagggcccggaccactcgtccgcgcgcccggagcgcttcctccagctgtgcgcc
cagaacaacatgacggtcgccatgccgacgtcgccgtcgaactacttccacctcctgcgg
tggcaggtgcacaacccgcaccacaagccgctggtcgtcttcacgccgaagtcgatgctg
cgcctgaaggccgccgcgtcgaaggcggacgagttcaccacgggcggcttccgcccggtc
atcggcgacgcgtcggtggacccggcggcggtgcggaaggtcgtcttctgcgcgggcaag
gtctactacgacctggaggccgagcgggtcaagcgcggcgtgacggacaccgcgatcatc
cgtatcgagcggctgtacccgctgccgggtgccgagctccaggcggagatcaagaagtac
ccgaacgccgagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccg
ttcatcgcgctcaacctgatcgaccacctcgacctggcggtcggcgcggacgtgccgcac
ggcgagcgcctgcgccgcatctcgcggccgcacggctcgtcccccgcggtgggttccgcg
aagcgccaccaggccgagcaggagcagctggtgcgcgaggtgttcgaggcgtga
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