Streptomyces californicus: I6J39_24610
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Entry
I6J39_24610 CDS
T07611
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scal
Streptomyces californicus
Pathway
scal00020
Citrate cycle (TCA cycle)
scal00630
Glyoxylate and dicarboxylate metabolism
scal00785
Lipoic acid metabolism
scal01100
Metabolic pathways
scal01110
Biosynthesis of secondary metabolites
scal01120
Microbial metabolism in diverse environments
scal01200
Carbon metabolism
scal01210
2-Oxocarboxylic acid metabolism
Module
scal_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scal_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
I6J39_24610
00630 Glyoxylate and dicarboxylate metabolism
I6J39_24610
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I6J39_24610
Enzymes [BR:
scal01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
I6J39_24610
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
I6J39_24610
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
I6J39_24610
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
I6J39_24610
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QRV30115
LinkDB
All DBs
Position
complement(5612655..5616470)
Genome browser
AA seq
1271 aa
AA seq
DB search
MSSQSPSNSSISTDQAGPGINPAAAFGANEWLVDEIYQQYLQDPTSVDRAWWDFFADYKP
GGSGTADKPAPGAGASGAPVAEAASAPAAAPAKAAPAAAPAAPAQPAPAKAAPAPAKAAP
APAKPAAEKKPAAAPAKPKAKADESTEASGGPEYVTLRGPSAAVAKNMNASLELPTATSV
RAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAEKDGKPTL
VKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIGKLGMDDF
TGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTL
TSTYDHRVIQGAASGEFLRVLSQLLLGENEFYDEIFKALRIPYEPVRWLKDIDASHDDDV
TKAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFAGK
TMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRPKPEREEQLRILRRLN
AAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAEARLDEVVIGMAHRGRLNVLA
NIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEA
VDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTV
HVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQAFN
KDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEAEQA
LQDFQGQLEKVFAEVREATSQPAAPHVPEPQAAFPVPVETAVSAEVVKRIAESQVNIPES
ITVHPRLMPQMQRRAASVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHA
VLVDQVTGEDYTPLLYLADDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQFGD
FVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTV
AMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASSMEEFTSGGFRPVIGDSTV
KAENVRKVVFVSGKLFYDLDAEREKRGDTETAIIRLERLYPLPGAEIQAEIAKYPNAEKY
LWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPRGSSPAVGSAKRHQAE
QTQLVNEVFEA
NT seq
3816 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagccggtccgggcatc
aacccggccgccgcgttcggcgccaatgaatggctcgtcgacgagatctaccagcagtac
ctccaggatcccacttcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggtgggtccggcacggcggacaagcccgctcccggcgccggggcctcgggggccccggtg
gccgaggccgcgtccgccccggccgccgccccggcgaaggccgcgcccgccgccgccccg
gccgcccccgcgcagccggcccccgccaaggccgccccggccccggcgaaggccgctccc
gccccggcgaagcccgccgcggagaagaagcccgccgcggcgccggccaagccgaaggcc
aaggccgacgagtccaccgaggcctcgggcggcccggagtacgtgacgctgcgcggcccc
tccgccgccgtcgcgaagaacatgaacgcctccctggagctgccgacggccacgtccgtc
cgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaag
cgcgcccgcggcgggaagatctccttcacccacctcatcgggtacgcgatggtgcaggcc
ctcaaggccatgccgtcgatgaactactccttcgcggagaaggacggcaagccgaccctg
gtcaagccggagcacgtcaacctgggtctggccatcgacctggtgaagccgaacggcgac
cgccagctggtcgtggcggccatcaagaaggccgagacgctcaacttcttcgagttctgg
caggcgtacgaggacatcgtccggcgcgcccgtatcggcaagctcggcatggacgacttc
accggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgtccactcggtgccc
cgcctgatgcccggtcagggcctcatcatgggcgtcggcgcgatggactacccggcggag
ttccagggcacctcgcaggacaccctcaacaagctcggcatctcgaaggtcatgacgctc
acgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgcgtg
ctgtcccagctgctgctcggcgagaacgagttctacgacgagatcttcaaggcgctgcgc
atcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtc
accaaggccgcgcgggtcttcgagctgatccactcctaccgggtccgcggccacgtcatg
gccgacaccgacccgctggagtaccaccagcgcaagcaccccgacctggacatcaccgag
cacggcctcaccctgtgggacctggagcgcgagttcgcggtcggcgggttcgccggcaag
acgatgatgaagctccgcgacatcctcggcgtgctgcgcgagtcgtactgccgcaccacc
ggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggaccgggtc
gagcgcccgcgtcccaagcccgagcgcgaggagcagctgcgcatcctgcgccggctgaac
gcggccgaggcgttcgagaccttcctgcagacgaagtacgtcggccagaagcggttctcc
ctggagggcggcgagtccgtcatcccgctgctcgacgccgttctcgactccgccgccgag
gcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtcctggcg
aacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctggacccg
cgctcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcaccttcacc
ggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcacctggaggcg
gtcgacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaacaagggcggc
acggacttcacggtcctgccggtcgcgctccacggcgacgcggccttcgcgggccagggc
gtcgtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtg
cacgtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgctcctcg
atgtacgccaccgatgtggcgcgcatgatcgaggcgccgatcatccacgtcaacggcgac
gacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccggcaggcgttcaac
aaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaac
ccggagttcaccaacccgcagatgtacaccctgatcgacaagaagcgctcggtgcgcaag
ctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggcggagcaggcg
ctccaggacttccagggccagctggagaaggtgttcgccgaggtccgcgaggccacctcg
cagccggccgccccgcacgtgccggagccgcaggccgcgttcccggtgccggtggagacg
gccgtctcggccgaggtcgtcaagcggatcgccgagtcccaggtcaacatccccgagtcg
atcaccgtccacccccgcctgatgccgcagatgcagcgccgcgcggcctcggtggagaac
ggcacgatcgactggggcatgggcgagaccctggccatcggttcgctgctgatggagggc
actccggtccggctcgccggccaggacagccgccgcggcacgttcggccagcgccacgcg
gtcctggtcgaccaggtcaccggcgaggactacaccccgctgctgtacctggcggacgac
caggcccggtacaacgtctacgactcgctgctctcggagtacgcggcgatgggcttcgag
tacggctactcgctggcgcgtccggagtcgctggtcatctgggaggcccagttcggtgac
ttcgtcaacggcgcgcagaccgtcgtggacgagttcatctcctcggccgagcagaagtgg
ggccagacctccggcgtcacgctgctgctgccgcacggctacgagggccagggcccggac
cacagctccgcgcgtcccgagcgcttcctccagatgtgcgcgcaggacaacatgacggtc
gcgatgccgaccctgccgtcgaactacttccacctgctgcgctggcaggtgcacaacccg
caccacaagccgctcatcgtcttcaccccgaagtcgatgctgcgtctgaaggcggcggcg
tcctcgatggaggagttcacctccggcggcttccgcccggtgatcggcgactccacggtc
aaggccgagaacgtccgcaaggtcgtcttcgtctcgggcaagctgttctacgacctggac
gccgagcgggagaagcgcggcgacacggagaccgcgatcatccggctggagcggctgtac
ccgctgcccggcgcggagatccaggccgagatcgcgaagtacccgaacgccgagaagtac
ctgtgggcccaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctg
atcgaccacctggacctcgcggtcggcgcggacgtgccgcacggcgagcggctgcgccgc
atctcgcggccgcgcggctcgtcccccgcggtcggttcggccaagcgccaccaggccgag
cagacgcagctggtcaacgaggtcttcgaagcctga
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