KEGG   Cupriavidus metallidurans: Rmet_4134
Entry
Rmet_4134         CDS       T00351                                 
Symbol
pdhA
Name
(GenBank) putative oxidoreductase (puryvate dehydrogenase E1 component, alpha subunit)
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
rme  Cupriavidus metallidurans
Pathway
rme00280  Valine, leucine and isoleucine degradation
rme00640  Propanoate metabolism
rme00785  Lipoic acid metabolism
rme01100  Metabolic pathways
rme01110  Biosynthesis of secondary metabolites
rme01210  2-Oxocarboxylic acid metabolism
Module
rme_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:rme00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Rmet_4134 (pdhA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Rmet_4134 (pdhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Rmet_4134 (pdhA)
Enzymes [BR:rme01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     Rmet_4134 (pdhA)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: ABF11001
UniProt: Q1LFS5
LinkDB
Position
megaplasmid:complement(708407..709510)
AA seq 367 aa
MGTVARFEIGFTRYLSPDGSPEPDLPDFARDPATLLPLYRAMVLTRQFDLKAIAMQRTGQ
IGTFASALGQEAIGVGVATAMRRDDVLVPSYRDHAAQFVRGVTMTESLLYWGGDERGSAF
AAVPYDFGNCVPIGTQVGHAAGVAYTFKLRQAPNVAVCILGDGGTSKGDFYEGMNMAGAW
HVPLVIVINNNQWAISMPRAKQTAAATLAQKAIAAGIPGEQIDGNDVIAVRQRVGAAIEH
ARHGGGPTLIEAVSYRLGDHTTADDASRYRDEASVKEAWRCEPIIRLRDYLARLGAWDAA
QEEALIKECQQAVGAAVQAYLALPHPDASAMFDCLYETLPDAMAEQLDTARQYDASGKTD
TSGAHHG
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgggcactgttgcgcgttttgaaatcggctttacccgctacctctcccccgacggctcg
ccagagcccgaccttcccgactttgcccgcgatccggccaccctgctgccgctctatcgc
gccatggtgctgacccggcagttcgatctcaaggccatcgcgatgcaacgtaccggccag
atcggcacgttcgcgtccgcgctgggccaggaagcgatcggcgtcggcgtggccacggcg
atgcgccgcgacgacgtgctggtgccgtcgtaccgcgatcatgccgcgcagtttgtgcgg
ggcgtcacgatgacggagagcctgctgtactggggtggcgacgaacgcggcagcgcgttt
gccgcagtgccatatgacttcggcaactgcgtgccgatcggcacccaggttggccatgcg
gccggcgtggcctacacgttcaagctgcgccaggcaccgaacgtggcggtgtgcatcctc
ggcgacggcggcacctcgaagggtgacttctacgaggggatgaacatggccggcgcgtgg
cacgtcccgctggtcatcgttatcaacaacaaccagtgggccatctcgatgccgcgcgcc
aagcagacggcggcggcgacgctggcccagaaggcgatcgcagcgggcattccgggcgaa
cagatcgacggcaacgacgtgattgccgtgcggcagcgcgttggcgcggccatcgaacat
gcgcgccacggcggcgggccgacgttgatcgaggcggtgagctaccgcctgggcgaccat
acgacagccgatgatgcgtcgcgctaccgggacgaggcatcggtcaaggaagcctggcgc
tgcgagcccattatccggctgcgagactacctggcccgcctcggcgcctgggacgccgcg
caggaagaggcgctgatcaaggaatgccagcaggccgtcggcgcggccgtgcaggcctat
cttgcgctgccgcatcccgatgcatcggcgatgttcgattgcctgtatgaaacgctgccc
gacgccatggccgaacaactcgacaccgcgcggcaatacgacgcctctggcaagaccgat
acctcgggagcccatcatggctga

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