KEGG   Penicillium oxalicum: POX_g08741
Entry
POX_g08741        CDS       T09521                                 
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
pou  Penicillium oxalicum
Pathway
pou00670  One carbon pool by folate
pou01100  Metabolic pathways
pou01240  Biosynthesis of cofactors
pou04981  Folate transport and metabolism
Module
pou_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:pou00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    POX_g08741
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    POX_g08741
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pou04147]
    POX_g08741
Enzymes [BR:pou01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     POX_g08741
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     POX_g08741
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     POX_g08741
Exosome [BR:pou04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   POX_g08741
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 74440915
NCBI-ProteinID: XP_049965654
LinkDB
Position
VII:605450..608613
AA seq 942 aa
MASRIDGTAIAKSIREGLKSEIEKAQASNPRFKPNLVIFQVGNRSDSSDNTGTYVRMKLK
AAQEANIICTLINVPESSTELELLQEITKANNDPSVHGILVQLPLPNHMSEHTITSAVAD
EKDVDGFGAINIGELAKRGGHPLFTPCTPLAVMELLKASGVDPAGKEAVVLGRSDIVGSP
VSYLLKNADATVTVCHSKTPDIARVVKNADIVVAAIGKTEFVKGEWLKPGAVVIDVGINY
KEDATKKSGQRLVGDVEFDSAVQVASQITPVPGGVGPMTVAMLLKNVVSAAKHYFDRQRD
RHITPLPLRLQTPVPSDIAISRAQYPKPITTVGSEVGIAPHELEPYGHTKAKVNLGVLDR
LSHRRNGRYILVCGITPTPLGEGKSTTTLGLTQALGAHLNRIAFANVRQPSQGPTFGIKG
GAAGGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIETRMFHEATQKDGALYKRLVPA
KKGVREFKPIMFRRLKKLGIEKTNPDDLTEEEIRRFARLDIDPETITWRRVLDVNDRHLR
GITVGQAPTEKGLSRETGFDISVASECMAILALSNSLDDMRERLGRMVVATSRSGDPVTC
DDLGAGGALAALMKDAIKPNLMQSLEGTPVLVHAGPFANISIGASSIIADKLALKLAGTE
LDEDHDAKTGFVVTEAGFDFTMGGERFFNIKCRSSGLSPDTVVIVATVRALKVHGGGPEI
SPGAPLPEVYRTENVDVLRAGCVNLRKHIANAKQYGVPVVVAINRFETDTEAEIAVIKEE
AIAAGAEDAVPANHWAEGGAGAVDLAKAVLVASSKPKDFKLLYDLNGSIQERIERIGKAM
YGAEKVEFSELAQKKVDTYTKQGFANLPICIAKTQYSLSHDPALKGAPTGFTVPIRDVRL
AVGAGYLYALAADIQTIPGLPTAPGYLNVDIDTETGEIDGLF
NT seq 2829 nt   +upstreamnt  +downstreamnt
atggcgtccagaatcgatggcaccgctattgcgaagagcatccgggagggcttgaagagc
gagattgaaaaggcacaggctagcaatcctcgtttcaagccaaacttggtgatcttccag
gtgggaaatcgttccgattcgagcgacaacacaggcacatacgttcgaatgaagttgaag
gctgctcaagaggccaacatcatttgcacactcatcaatgtccccgagtctagtaccgag
ttggagcttctccaggaaatcacaaaggccaacaatgatccttcagtccatggtattctg
gtgcaactgcccctgcccaatcacatgtccgagcacaccatcacatcagctgtggccgac
gaaaaggatgtcgatggattcggtgcgattaacatcggtgagctggccaagcggggtgga
caccctctgttcactccttgcacacctcttgctgtgatggagctgttgaaggcaagtggc
gttgatcccgccggcaaggaagccgttgtcctgggtcgaagtgacattgtgggtagtcct
gtcagctatctgctgaagaacgcagatgccaccgtcacagtctgtcactcaaagacacct
gatattgcgcgggtagttaagaatgccgacatcgttgtggccgccatcggtaagaccgaa
ttcgtcaagggcgagtggctcaagcccggtgctgttgttatcgacgtcggtatcaactac
aaggaggatgcgacgaagaagtctggacagcgtctcgttggtgacgttgaatttgattcc
gctgtccaagtcgcctcgcagatcactccagttccgggtggcgttggtcccatgaccgtt
gctatgttgttgaagaacgtggtctccgccgccaagcactactttgatagacagcgagac
cgtcacatcactcctctgccactcagattgcagacacccgttccatctgacattgcaatc
tcccgtgcgcaatatcccaagcctatcactacagtaggttcggaagtcggcattgctcct
cacgagctcgagccgtacggtcacaccaaggccaaggtcaaccttggagtacttgatcgc
ctgtcacaccgccgtaatggtcgttacattctggtttgcggtatcacccctacgcccctt
ggcgagggcaagtctacgactactctcggcctcactcaggctttgggtgctcacttgaac
cgcattgcgtttgccaacgttcgtcagcccagtcaaggcccgacctttggtattaaaggt
ggtgctgctggcggtggttacagtcaggtcatcccaatggacgagttcaacttgcacttg
accggcgacattcacgcgattactgcggccaacaatctccttgccgctgcaattgagact
cgcatgttccacgaagctacacaaaaggatggcgctctttacaagcgccttgtgccagcc
aagaagggcgtgcgcgagttcaagcctatcatgttccgccgattgaagaagctcgggatc
gagaagaccaaccccgacgatctgaccgaagaggagatccgacgctttgctcgactggac
attgaccccgagaccattacttggcgtcgtgttctcgatgtcaacgaccgtcatcttcgt
ggcatcaccgttggccaggctcccactgagaagggactgtcccgtgagaccggctttgat
atctccgttgccagtgagtgcatggccatcttggctctcagcaatagcctggatgatatg
cgtgaacgtcttggacgcatggttgtcgctacctctcgcagtggtgaccccgtgacctgc
gacgaccttggtgcgggaggcgctcttgcggctctgatgaaagatgcgatcaagcccaac
ctcatgcaaagtcttgagggcactcccgtcttggtgcatgctggtccattcgccaacatt
agtatcggtgctagctccatcattgcagacaagctggctctgaagctggcgggtactgag
cttgatgaagaccacgacgccaagaccggtttcgtggtcaccgaggctgggttcgacttc
accatgggtggtgagcggttcttcaacatcaagtgccgctcgtccggtctttctcccgac
acggtcgtgatcgtggctactgtccgtgccttgaaagtgcacggtggtggtcccgagatc
agccctggcgcccccctgcccgaggtgtatcggacggaaaacgttgacgttcttcgcgct
ggctgtgtcaacctgcgcaaacacattgccaacgcgaagcagtacggtgtccccgttgtg
gttgccatcaaccgcttcgagactgacactgaggctgagattgctgtgataaaggaggag
gctattgctgctggtgccgaggacgcggtcccggctaaccactgggctgaaggtggtgcg
ggtgctgtcgatttggccaaggccgtgcttgtcgccagctccaagcccaaagacttcaag
ctgctgtacgatctgaatggcagtatccaggagcgcattgagcgcattggtaaggccatg
tacggtgccgagaaggttgagttcagtgagctcgcccagaagaaggtcgacacatatacc
aagcagggctttgccaacttgcccatctgtattgccaagacacaatactcgctcagtcac
gaccctgccctgaagggtgctcccaccggattcaccgttcccatccgggatgtgagattg
gccgtgggtgctggatacctctacgccttggccgctgatattcaaaccatccccggattg
cccactgcccccgggtatctaaacgtggacatcgacacagagactggagagattgacggg
ttgttttag

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