Peromyscus leucopus (white-footed mouse): 114696394
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Entry
114696394 CDS
T07241
Symbol
Tyms
Name
(RefSeq) thymidylate synthase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00240
Pyrimidine metabolism
pleu00670
One carbon pool by folate
pleu01100
Metabolic pathways
pleu01232
Nucleotide metabolism
pleu01523
Antifolate resistance
pleu04981
Folate transport and metabolism
Module
pleu_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
114696394 (Tyms)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114696394 (Tyms)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
114696394 (Tyms)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114696394 (Tyms)
Enzymes [BR:
pleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
114696394 (Tyms)
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GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
114696394
NCBI-ProteinID:
XP_028729892
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Position
13:complement(29316943..29329162)
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AA seq
307 aa
AA seq
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MPAAGSEMQSAAQQQGAEAPPHGELQYLGQVEHIMRCGFKKEDRTGTGTLSVFGMQARYS
LRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSAR
QEGDLGPVYGFQWRHFGADYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKD
LPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPG
DFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPT
IKMEMAV
NT seq
924 nt
NT seq
+upstream
nt +downstream
nt
atgccggctgcgggctccgagatgcagtccgccgctcagcagcagggcgcggaggcaccg
ccgcacggggagctgcagtacctgggccaggtggagcacattatgcgctgcggtttcaag
aaggaggaccgcacgggcacgggcaccttgtccgtgttcggcatgcaggcgcgatacagc
ctgagagatgaatttcctctgctcacaaccaaacgagtgttctggaagggtgttttggag
gagttgctgtggtttatcaaggggtccacaaatgctaaagaactgtcctccaagggagtg
agaatctgggatgccaatgggtcccgagattttctggacagcctgggattctctgcacgg
caggaaggggacctgggccccgtttatggtttccagtggagacattttggagcagactac
aaagacatggattcagattactcgggtcaaggagtcgaccagctgcaaaaagtgattgac
accatcaaaaccaaccctgatgacagaagaatcatcatgtgtgcctggaacccaaaagat
cttcccctgatggcactgcctccctgccatgccctctgtcagttctatgtggtgaatggg
gagttgtcttgccagctttaccagcggtcaggagacatgggcctgggcgtgcccttcaac
atcgccagctatgccctgctcacctacatgattgcacacatcaccggcctgaagccaggt
gattttgtccatacattgggagatgcacatatttacctgaatcatatcgagccactgaaa
attcagcttcagcgagagccacgacctttcccaaagctcaaaatccttcgaaaagttgag
acaattgatgatttcaaagttgaagactttcagattgaaggttataatccacatccaacg
attaaaatggaaatggctgtttag
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