KEGG   Pochonia chlamydosporia: VFPPC_00144
Entry
VFPPC_00144       CDS       T09407                                 
Name
(RefSeq) C-1-tetrahydrofolate synthase, mitochondrial precursor
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
pchm  Pochonia chlamydosporia
Pathway
pchm00670  One carbon pool by folate
pchm01100  Metabolic pathways
pchm01240  Biosynthesis of cofactors
pchm04981  Folate transport and metabolism
Module
pchm_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:pchm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    VFPPC_00144
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    VFPPC_00144
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pchm04147]
    VFPPC_00144
Enzymes [BR:pchm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     VFPPC_00144
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     VFPPC_00144
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     VFPPC_00144
Exosome [BR:pchm04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   VFPPC_00144
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall
Other DBs
NCBI-GeneID: 28844222
NCBI-ProteinID: XP_018148178
UniProt: A0A179G2K5
LinkDB
Position
1:748140..751300
AA seq 939 aa
MTARILDGTAIAKSIRERIGAEIAEKQKLNPRYKPSLKIIQVGDRSDSSTYVRMKLKAAA
EAGVACELIQFPVDTTEPELLDQIRRLNHDSTVNGILVQLPLPANISEYNITSSVADEKD
VDGFGTNNIGELAKRGGAPIFTPCTPKGVMYMLKEAGIQIAGKTAVVLGRSNIVGGPVSY
LLRHADATVIVCHSKTQGLENYLKHADIVIAAIGQARFVKAEWLKEGAVVIDVGTNFIPD
ASKKSGQRMVGDVDFDGASKVASVITPVPGGVGPMTVAMLLQNVVEATNLFFEKEKIRKT
IPIPLKLKSPVPSDIAISRDQTPKQITRIAAEVGIAPHELEPYGAYKAKVDLDLLKRLDH
RRNGRYVVVTGITPTPLGEGKSTTTMGLAQALGAHVGRLTFANVRQPSQGPTFGIKGGAA
GGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIETRIFHENTQKDGPLYRRLVPVKNG
VRKFVPVMFRRLKKLGIDKTNPDDLTEDEIRRFARLDIDPETITWRRVLDVNDRHLRGVT
VGTAPTEKGQSRETGFDISVASECMAILALSTSLADMRERLGRMVVATSRGGDPVTCDDI
GAGGALTALMKDAIKPNLMQTLEGTPVFVHAGPFANISIGQSSIIADKLALKLAGTEPDE
NPSESAGFVVTEAGFDFTMGGERFFNIKCRTSGLVPDVVVVVATVRALKVHGGGPPIAPG
APLDPVYKQENVEILRAGCVNLKKHISNAKSFGVPVVVAINKFATDTDAEIAVVREEALS
AGAEDAILADHWAQGGQGAVDLAKGVVAACEKPKELTLTYGLDGTIQERIEAIGQKMYGA
AKVEFSELAQKKVDTYTRQGYGNLPICIAKTQYSLSHDPDLKGAPTGFTVPIRDVRMAAG
AGYLYALAADIQTIPGLPTAPGYLNVDVDTETGEIDGLF
NT seq 2820 nt   +upstreamnt  +downstreamnt
atgactgctcgaatcttggatggcactgccatcgccaagagcatccgtgagaggattggt
gcagaaattgccgagaagcaaaagctcaatccgcgctacaagccttcgctcaagatcatt
caagttggcgaccgctcagactcttccacttatgtgcgcatgaagctcaaggctgccgca
gaggctggcgtcgcttgtgaacttatccaattccccgtagacaccaccgaacccgaactc
ctggaccagattcgtcgcctcaaccacgactccactgtcaacggcatcttggttcagctg
cccctacccgccaacatctccgagtacaacatcacctcttccgttgccgacgaaaaggat
gtcgatggcttcgggactaacaacattggcgagctggccaaacggggaggcgccccaatc
ttcaccccttgcacccccaagggcgtcatgtacatgctcaaagaggctggcattcagatc
gccggaaagacggcagtcgttcttggccgaagcaacattgttggtggacccgtcagctac
ctgttgcgacatgctgatgccaccgtcattgtctgccactccaagacgcagggactggag
aactatctcaagcacgctgacattgtcattgctgccattgggcaagctcgctttgtcaag
gctgaatggttaaaggagggtgccgttgtcattgatgtcggaactaactttattcccgat
gcctccaagaagagtggccagcgtatggttggtgatgtcgactttgacggtgcttccaag
gttgcatcggtcatcactcctgtgcctggtggcgttggccccatgacagttgccatgctt
ttgcaaaacgttgtagaagctaccaatctgttcttcgagaaggagaagattagaaagacg
atccccatccccttgaaactcaaaagccccgtgccgtctgatatcgccatctcccgagat
cagacgcccaagcaaattactcgaattgcggccgaggttggcattgctccccacgaactg
gagccctacggtgcctacaaggccaaggttgatcttgacctgctgaagcgcctggaccac
cgcagaaatggtcgttacgtcgtcgtcactggtatcacgccaacgccccttggagaaggc
aagtccaccaccaccatgggccttgcccaggctctgggagcccatgtgggcagacttacc
ttcgccaatgtacgacaacccagtcagggcccgactttcggaatcaagggcggcgctgca
ggcggtggttacagtcaggtcattcccatggatgagtttaacttgcacttgaccggcgac
atccacgccatcactgccgccaacaatctcttggccgctgccatcgaaacccgcatcttc
cacgaaaacacccaaaaagacggaccgctctaccgaagactagtccccgtaaagaatgga
gtccgaaagttcgtcccggtcatgttccgtcggttgaagaagctgggcattgacaagacc
aaccctgatgatctcaccgaggacgaaattcgacgatttgcccgtctcgatattgaccca
gagaccatcacttggaggcgtgttctcgacgtcaacgatcgccacctgcgaggcgtcact
gtcggcacggcacccacagagaagggtcaatcccgagaaaccggcttcgatatctccgtt
gccagtgagtgcatggctattctcgctttgagcacaagtttggcggacatgcgagagcgt
ctgggccgcatggtcgttgctacttctcgcggcggcgacccagtcacttgcgacgacatt
ggcgccggaggcgctttgacggccctgatgaaggatgccattaagcccaaccttatgcaa
accctggaaggaactcctgttttcgtccacgctggtccgtttgccaacattagtatcggc
cagagttccatcattgccgacaaactggcattgaagctggctggcaccgagcctgacgag
aaccccagtgaatctgcaggtttcgttgtcaccgaggctggctttgatttcaccatgggc
ggtgaacgattcttcaacatcaaatgccgtacatctggcctcgtccccgatgttgtcgtc
gtcgtggctaccgtgcgtgctctcaaggtccatggtggtggtcctcctattgcccctggt
gctcctcttgaccctgtctacaagcaagagaatgtggaaattctgcgcgctggttgtgtg
aacctcaagaagcacatcagcaacgccaagtcatttggtgttccggtcgtcgttgccatc
aacaagttcgctaccgacacggatgctgagattgccgttgtccgcgaggaagcactgtct
gcgggcgccgaagatgccatcctggcggaccactgggctcaaggtggtcaaggagctgtt
gacctcgccaagggtgttgtcgctgcttgcgaaaagcccaaagagctcacgcttacctat
ggccttgacggcaccattcaggagcgcattgaagccattggccagaagatgtacggtgct
gccaaggttgagttcagcgagctggctcagaaaaaggtcgacacctacaccagacagggt
tacggaaacctgcccatttgtattgccaagacgcagtattctctctcccacgacccggat
ctgaagggtgcacccactggctttaccgttcccattcgggatgtccgtatggctgctggt
gcaggatatctgtatgctttggcggctgatatccagaccatccccggacttcccacggcc
ccaggttatctcaacgttgatgttgatactgagactggcgagattgacggtctgttctag

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