KEGG   Physeter catodon (sperm whale): 102988335
Entry
102988335         CDS       T06011                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
pcad  Physeter catodon (sperm whale)
Pathway
pcad00240  Pyrimidine metabolism
pcad00670  One carbon pool by folate
pcad01100  Metabolic pathways
pcad01232  Nucleotide metabolism
pcad01523  Antifolate resistance
pcad04981  Folate transport and metabolism
Module
pcad_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    102988335 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102988335 (TYMS)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    102988335 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102988335 (TYMS)
Enzymes [BR:pcad01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     102988335 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 102988335
NCBI-ProteinID: XP_023976504
Ensembl: ENSPCTG00005018401
UniProt: A0A2Y9SLC5
LinkDB
Position
19:complement(34800462..34812080)
AA seq 315 aa
MPAAGSELPHPTSPPAAQEQGAESRPPPPHGELQYLGQIEHILRCGFRKDDRTGTGTLSV
FGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFL
DSLGFSTRAEGDLGPVYGFQWRHFGAEYKDMDSDYSHQGVDQLQKVIDTIKTNPDDRRII
LCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIA
HITGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQI
EGYNPHPTIKMEMAV
NT seq 948 nt   +upstreamnt  +downstreamnt
atgcccgccgccggctccgagctgccgcacccgacgtcgccgcccgccgcgcaggagcag
ggcgccgagtcgcggccgccgccgccgcacggcgagctgcagtacttggggcagatcgag
cacatcctccgctgcggctttcggaaggatgaccgcacgggcaccggcaccctgtcggtg
ttcggcatgcaggcgcgctacagcctgagagatgaatttcctctgctgacaaccaaacgt
gttttctggaagggtgttttggaggagttgctgtggtttatcaagggatccacaaatgct
aaggagctgtcttccaagggagtgaaaatctgggatgccaatgggtcccgagacttcttg
gacagcctgggattctccaccagagcagaaggggatttaggcccagtttatggctttcag
tggaggcattttggcgccgaatacaaagatatggattcagattattcacatcaaggagta
gatcaactgcaaaaagtgattgacacaatcaaaaccaaccctgacgacagaagaatcatc
ctatgtgcttggaatccaaaagatctccctctcatggccctacccccgtgccacgccctt
tgccagttctacgtggtgaacggtgagctgtcctgccagctgtaccagaggtcaggagac
atgggcctgggtgtgcccttcaacatcgccagctacgccctgctcacctacatgatcgca
cacatcacgggcctgaagccaggtgactttgtacacactttgggagatgcgcacatttac
ctgaatcacattgagccgctgaaaattcagcttcagcgagaaccaaggcctttccccaag
ctcaaaatccttcgaaaagttgagaaaattgatgacttcaaggccgaagactttcagatt
gaaggctacaatcctcacccgactattaaaatggaaatggctgtttag

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