KEGG   PATHWAY: mmer00330
Entry
mmer00330                   Pathway                                
Name
Arginine and proline metabolism - Mercenaria mercenaria (northern quahog)
Class
Metabolism; Amino acid metabolism
Pathway map
mmer00330  Arginine and proline metabolism
mmer00330

Module
mmer_M00015  Proline biosynthesis, glutamate => proline [PATH:mmer00330]
mmer_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mmer00330]
mmer_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mmer00330]
mmer_M00970  Proline degradation, proline => glutamate [PATH:mmer00330]
mmer_M00972  Proline metabolism [PATH:mmer00330]
Other DBs
GO: 0006525 0006560
Organism
Mercenaria mercenaria (northern quahog) [GN:mmer]
Gene
123523817  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
123546532  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
123524719  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
123524721  ornithine decarboxylase-like isoform X2 [KO:K01581] [EC:4.1.1.17]
123526648  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
123564305  antizyme inhibitor 2-like [KO:K01581] [EC:4.1.1.17]
123542516  ornithine decarboxylase-like isoform X1 [KO:K01581] [EC:4.1.1.17]
123533914  spermidine synthase-like [KO:K00797] [EC:2.5.1.16]
123527375  spermidine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
123551345  S-adenosylmethionine decarboxylase proenzyme 1-like [KO:K01611] [EC:4.1.1.50]
123523139  putative amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
123524764  putative amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
123559568  amiloride-sensitive amine oxidase [copper-containing]-like [KO:K11182] [EC:1.4.3.22]
123559569  amiloride-sensitive amine oxidase [copper-containing]-like [KO:K11182] [EC:1.4.3.22]
123538506  membrane primary amine oxidase-like [KO:K11182] [EC:1.4.3.22]
123532570  putative amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
123566673  putative amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
123566674  putative amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
128559541  amiloride-sensitive amine oxidase [copper-containing]-like [KO:K11182] [EC:1.4.3.22]
123547363  spermine oxidase-like [KO:K12259] [EC:1.5.3.16 1.5.3.-]
123562630  spermine oxidase-like [KO:K12259] [EC:1.5.3.16 1.5.3.-]
123523472  uncharacterized protein LOC123523472 [KO:K13366] [EC:1.5.3.14 1.5.3.16 1.5.3.-]
123557659  uncharacterized protein LOC123557659 [KO:K13366] [EC:1.5.3.14 1.5.3.16 1.5.3.-]
123526626  uncharacterized protein LOC123526626 [KO:K13366] [EC:1.5.3.14 1.5.3.16 1.5.3.-]
123532668  uncharacterized protein LOC123532668 [KO:K17839] [EC:1.5.3.17 1.5.3.-]
128556589  aldehyde dehydrogenase family 16 member A1-like [KO:K00128] [EC:1.2.1.3]
123522903  aldehyde dehydrogenase 1A1-like [KO:K00128] [EC:1.2.1.3]
123551393  aldehyde dehydrogenase family 16 member A1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
123566639  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
123566373  alpha-aminoadipic semialdehyde dehydrogenase-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
123531280  4-trimethylaminobutyraldehyde dehydrogenase-like isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
128546597  LOW QUALITY PROTEIN: 4-trimethylaminobutyraldehyde dehydrogenase A-like [KO:K00149] [EC:1.2.1.47 1.2.1.3]
123537357  cytosolic non-specific dipeptidase-like isoform X1 [KO:K08660] [EC:3.4.13.18]
123534519  carnosine synthase 1-like isoform X1 [KO:K14755] [EC:6.3.2.11]
123525736  carnosine synthase 1-like [KO:K14755] [EC:6.3.2.11]
123541963  carnosine synthase 1-like [KO:K14755] [EC:6.3.2.11]
123542593  carnosine synthase 1-like [KO:K14755] [EC:6.3.2.11]
123527748  thialysine N-epsilon-acetyltransferase-like isoform X1 [KO:K00657] [EC:2.3.1.57]
123527917  uncharacterized protein LOC123527917 [KO:K00657] [EC:2.3.1.57]
128548557  thialysine N-epsilon-acetyltransferase-like [KO:K00657] [EC:2.3.1.57]
123563581  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
123563582  amine oxidase [flavin-containing] A-like [KO:K00274] [EC:1.4.3.4]
123554748  amine oxidase [flavin-containing] B-like [KO:K00274] [EC:1.4.3.4]
128558587  guanidinobutyrase-like [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
123549239  amidase-like isoform X1 [KO:K01426] [EC:3.5.1.4]
123550564  amidase-like [KO:K01426] [EC:3.5.1.4]
123529970  amidase-like [KO:K01426] [EC:3.5.1.4]
123529971  amidase-like isoform X1 [KO:K01426] [EC:3.5.1.4]
123530182  amidase-like [KO:K01426] [EC:3.5.1.4]
123524662  opine dehydrogenase-like [KO:K23233] [EC:1.5.1.11]
123525369  octopine dehydrogenase-like [KO:K23233] [EC:1.5.1.11]
123525370  opine dehydrogenase-like [KO:K23233] [EC:1.5.1.11]
123551807  arginine kinase-like isoform X1 [KO:K00934] [EC:2.7.3.3]
123541493  arginine kinase-like [KO:K00934] [EC:2.7.3.3]
123552536  arginine kinase-like [KO:K00934] [EC:2.7.3.3]
123552899  arginine kinase-like [KO:K00934] [EC:2.7.3.3]
123533726  nitric oxide synthase, brain-like [KO:K13240] [EC:1.14.13.39]
123536234  arginase, hepatic-like [KO:K01476] [EC:3.5.3.1]
123547244  ornithine aminotransferase, mitochondrial-like [KO:K00819] [EC:2.6.1.13]
123540473  pyrroline-5-carboxylate reductase 1, mitochondrial-like [KO:K00286] [EC:1.5.1.2]
123534586  proline dehydrogenase 1, mitochondrial-like [KO:K00318] [EC:1.5.5.2]
123527187  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial-like [KO:K00294] [EC:1.2.1.88]
123547783  delta-1-pyrroline-5-carboxylate synthase-like isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
123532862  probable proline iminopeptidase [KO:K01259] [EC:3.4.11.5]
128546997  probable proline iminopeptidase isoform X1 [KO:K01259] [EC:3.4.11.5]
123546146  cytosol aminopeptidase-like [KO:K11142] [EC:3.4.11.1 3.4.11.5]
123535210  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
123526930  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
123538986  prolyl 4-hydroxylase subunit alpha-3-like [KO:K00472] [EC:1.14.11.2]
123562853  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
123532764  uncharacterized protein LOC123532764 [KO:K00472] [EC:1.14.11.2]
128550233  prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [KO:K00472] [EC:1.14.11.2]
123530308  hydroxyproline dehydrogenase-like isoform X1 [KO:K11394] [EC:1.5.5.3]
123546382  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
123548409  aspartate aminotransferase, mitochondrial-like isoform X1 [KO:K14455] [EC:2.6.1.1]
123547812  4-hydroxy-2-oxoglutarate aldolase, mitochondrial-like [KO:K18123] [EC:4.1.3.16]
123524800  D-aspartate oxidase-like isoform X1 [KO:K00273] [EC:1.4.3.3]
123545553  trans-L-3-hydroxyproline dehydratase-like isoform X1 [KO:K18384] [EC:4.2.1.77]
123536541  trans-L-3-hydroxyproline dehydratase-like [KO:K18384] [EC:4.2.1.77]
123536542  trans-L-3-hydroxyproline dehydratase-like [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mmer00020  Citrate cycle (TCA cycle)
mmer00220  Arginine biosynthesis
mmer00250  Alanine, aspartate and glutamate metabolism
mmer00260  Glycine, serine and threonine metabolism
mmer00270  Cysteine and methionine metabolism
mmer00310  Lysine degradation
mmer00410  beta-Alanine metabolism
mmer00470  D-Amino acid metabolism
mmer00480  Glutathione metabolism
mmer00630  Glyoxylate and dicarboxylate metabolism
mmer00650  Butanoate metabolism
mmer00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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