Ochotona princeps (American pika): 101523838
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Entry
101523838 CDS
T07609
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi05200
Pathways in cancer
opi05223
Non-small cell lung cancer
opi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101523838 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101523838 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
101523838 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101523838 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
opi04090
]
101523838 (ALK)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101523838 (ALK)
Protein kinases [BR:
opi01001
]
Receptor tyrosine kinases (RTK)
ALK family
101523838 (ALK)
CD molecules [BR:
opi04090
]
Proteins
101523838 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
101523838
NCBI-ProteinID:
XP_004582764
LinkDB
All DBs
Position
2:complement(22270477..22999302)
Genome browser
AA seq
1624 aa
AA seq
DB search
MQPSSGGMRAIGLLWLLLLLLSAAASGSGAAAGQHAGTPAMGPPLQPREPLSYSRLQRKS
LAVDFVVPSLFRAYVRDLLLPQEPRAGLTEARGVLALDCAPLLRLLGPPSGVSWASPVPA
LSRVLKGGSVRKLRRAKQLVLELGEESILEGCLGPPEEAAAGLLQFNLSELFSWWIRHGE
GRLRIRLMPEKKASEGGREGRLSTAIRASQPRLLFQILGAGASSLESPTHMPSLPPDYFS
WNLTWTMKDSFPFLSHRSRYGLECSFDFPCELEYFPPLHDRGNQSWSWRRVPPEEASQMD
FLDGPEAERAKDMPRGSFLLLNTSAESKHTILSPWMRSSSEHCTLAVSVHRHLQPTGRYV
AQLLPHNEPGREILLVPTPGKHGWTVLQGRVGRPEHPFRVALEYISSGNRSLSAVDFFAL
KNCSEGTSPGSKMALQSSFTCWNATVLRLGQACDFHQDCSQGEDEGHLCSKLPTGFYCNF
EDGLCGWTQDTLSSQGPRWQVRTMKDARSQGHQDHALLLSTTEVATSESATVTSATFPAP
MKNSPCELRMAWLVRGVLRGNVSLLLVENKTGKEQSRMLWHVPPSNGLSLWQWVVLPLLD
VSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKMPPNAEPKSRNLFEGISNK
DLKPREPTPGTPTFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNQSVVVGSEGPLKGI
QIWTVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDAC
PSTNQLIQKVCIGENKVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAG
GGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWSDNTSLLWAGKSLLEGATGG
HSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGISFISPLG
ILYTPALKVMEGHGEVNIKHYLNCSHCEIDECHMDPETHKVICFCDHGTVLAQDGVSCIV
SPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQLELQSPEYKLSKL
RTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPSDPS
PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGD
LKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGTG
RVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIF
SLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI
EYCTQDPDVINTALPIEYGPLVEEEEKVPMRPKDPEGVPPLLVSPAQATREEVPAPAAPP
ALPATSSGRVAKKPAAAEVPARGPRGSAMEGGHVNMAFAQSTVPSELPKGQASRNKPTSL
WNPTYGSWFTEKPARKNNALAKKEPQDRGHPGQEGSCTVPPGGGGSGGVAPGRLPGGSLL
LEPAALTASMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAAAGPGAGRYEDPMLKAKGSGK
QPGP
NT seq
4875 nt
NT seq
+upstream
nt +downstream
nt
atgcagccctcctccggcgggatgcgagccatcgggctcctgtggctgttgctgctgctg
ctctcggcggcagcctcgggctctggggccgctgctggccagcacgcgggcaccccggcc
atggggccgccactgcagccccgggagccgctcagctactcgcgcctgcagaggaagagc
ctggccgtggacttcgtggtgccctcgctcttccgcgcctacgtcagggacctgctgctg
cctcaggagcccagggcgggcctgaccgaggcgcgtggcgtcctggccctggactgcgcc
ccgctgctgaggctgctggggccgccgtctggggtgtcctgggcatccccggtcccggcg
ctgtccagagtgctgaagggcggctctgtgcgcaagctccggcgcgccaagcagctggtg
ctggagctgggcgaggagtcgatcctggagggctgcctggggcctccagaggaggcggcc
gctggactgctccagttcaacctcagcgagctgttcagctggtggattcgccacggcgag
gggcggctgaggatccgcctgatgcccgagaagaaggcgtcggaagggggcagagaagga
aggctgtccacagccatccgcgcttcccagccacgccttctcttccagatccttggcgct
ggtgccagctccttggaatcaccaacacacatgccttctcttcctcccgactacttctcg
tggaatctgacctggacaatgaaagattccttccctttcctgtctcatcgaagccgatat
ggtctggagtgcagctttgatttcccctgcgagctggagtacttccctcccctgcatgac
cgcgggaaccagagctggtcgtggcgccgtgtaccacctgaggaggcatcccagatggac
tttctggatggacccgaggcagagcgcgccaaggacatgcccagaggctccttcctcctc
ctcaacacctcagctgaatccaagcacaccatcctgagcccctggatgagaagcagcagt
gagcactgcacgctggccgtctcggtacacaggcacctacagcccacagggaggtatgtg
gcccagctgctgccccacaacgagcctggaagagagatcctcctggtgcccactccaggg
aagcatggctggaccgtgctgcagggaagagtcgggcgcccagagcacccattccgagtg
gccctggaatacatctccagcgggaaccgaagcctgtctgcagtggacttcttcgccctg
aagaactgcagtgaaggaacgtccccgggctccaagatggcattacagagttccttcact
tgttggaatgcgacagtactccggctcgggcaggcctgtgacttccaccaggactgctcc
cagggagaagacgagggccacctgtgcagtaaactccctactggcttttactgcaacttt
gaagatgggttgtgtggctggacccaagacacactctcctcccagggacctcggtggcag
gtcaggaccatgaaggatgcccggtcccagggccaccaagatcatgccctgctgctcagc
accaccgaggtcgccacatctgagagcgctaccgtgaccagtgctacattcccagcacca
atgaagaattctccatgtgagctccgaatggcctggctcgtccgcggagtcctgagggga
aacgtgtccttgctgctagtggagaacaagaccgggaaggaacaaagcaggatgctctgg
catgttcctcccagcaatggcctgagcctgtggcagtgggtagtgttaccactcctcgac
gtgtctgacaggttctggctccaaatggtcgcgtggtggggacaaggatccagagccaca
gtggccttcgacaacatctccatcagcttggactgctacctcaccatcagcggagaagac
aaaatgccaccgaatgcagagcccaagtcaagaaatctgtttgaggggatctcaaacaag
gacttgaaacccagagaacctacacctgggacccccacctttgaccctacagttcactgg
ctgttcaccacgtgcggggccagcggacctcatggccccacgcaggcccagtgcaacaac
gcctatcagaactccaaccagagtgtggtggtgggaagcgaaggccccctgaaaggcatc
cagatctggacagtgccggccaccgacacttacagcatttcaggctatggagccgctggc
ggcaaaggcggaaagaacaccatgatgcggtcccatggtgtgtctgtgctgggcatcttc
aacttggagaaggacgacacgctctacatactggtcgggcagcagggcgaggatgcctgt
cccagcacaaaccagttaattcagaaagtctgcatcggtgagaacaaggtgatcgaggag
gagatccgtgtgaacagaagtgtgcacgagtgggcaggaggaggcggcggaggtggagga
gccacctatgtctttaagatgaaggatggagtgcccgtgccgctgatcattgcggctggc
ggtggcggcagagcctatggggccaagacagacacattccacccggagaggctcgagaac
aactcctcggtcctggggctaaacggcaattccggagccgcaggtggcggaggtggctgg
agtgataacacttccttgctctgggccggaaagtctttgctggagggtgccaccggagga
cattcctgcccccaggccatgaagaagtgggggtgggagacaagagggggtttcggaggg
ggtggaggggggtgctcctcaggtggaggaggcggaggatatataggcggcaacgcagcc
tcaaacaatgaccctgaaatggatggggaagatgggatttcctttatcagtccactgggc
atcctgtacaccccggctttgaaagtgatggagggccatggggaagtgaatattaagcat
tatctaaactgcagtcactgtgagatagacgagtgtcacatggaccccgagactcacaag
gtcatctgcttctgcgaccatggaacggtgctggcccaggatggtgtctcctgcattgtg
tcgcccaccccagagccccatctgccgctctcactgatcctctctgtggtcacctctgct
ctagtggccgcccttgtcctggctttctctggcatcatgattgtgtaccgtcgcaagcac
caggagctgcaggccatgcagctggagctgcagagccctgagtataagctgagcaagctc
cgcacctcgaccatcatgaccgactacaaccctaactactgcttcgccggcaagacctcc
tccatcagtgacctgaaggaggtgccacggaagaacatcaccctcatccggggtctgggc
catggtgcctttggggaagtatatgaaggccaggtgtctgggatgcccagcgacccaagc
cccctgcaagtggctgtcaagaccctgccggaggtgtgttctgaacaggacgagctggat
ttcctcatggaggccttgatcatcagcaaattcaaccaccagaacattgtgcgctgcatc
ggagtcagtctacaagccctaccccgcttcatcctgctggagctcatggcaggaggagac
ctcaagtctttcctccgggagacccggcctcgtccgaatcagccctcctccctggccatg
ctggacctgctgcatgtagctcgggacattgcctgtggctgtcagtacctagaggaaaac
cacttcatccaccgggacattgctgccaggaactgcctcttgacctgtccgggcacggga
agggtggcaaagattggagactttggcatggcacgagacatctacagagcaagctactac
agaaagggtgggtgtgccatgctgccagttaagtggatgcccccagaggccttcatggaa
ggaatatttacttccaaaacagacacctggtccttcggagtgctgctgtgggaaatcttc
tccctcggatacatgccgtaccccagcaaaagcaaccaggaggtcctggagtttgtcacc
agtggaggccggatggacccgcccaagaactgccccgggcctgtataccggataatgact
caatgctggcagcatcaacctgaagacaggcccaactttgccatcatcttggagaggatt
gaatactgcacccaggaccctgatgtgatcaacaccgccctgcccattgaatacgggccc
ctggtggaagaggaagaaaaggtgcccatgcggcccaaggaccccgagggcgtccctcca
ctgctggtgtctccagcccaggccacacgggaggaggtgcccgccccagccgcgccacct
gctctgccggccacttcctcaggcagagtcgccaagaaacccgcagcggccgaggtcccc
gcccgaggccctagagggtcagccatggaggggggacacgtgaacatggccttcgcccag
tctaccgtgccgtcagagctgcccaagggccaggcgtccagaaacaagccgaccagcctg
tggaacccgacctacggctcatggtttaccgagaaacccgccagaaagaacaatgccctg
gccaagaaggagccgcaggaccgggggcacccggggcaggagggaagctgtactgtcccg
ccgggcggtggtggcagcggcggtgtagcccccggccgcctcccggggggctccctgctc
ctggagccggcggcgctgactgccagcatgaaggaggtgccgctgttcaggctgcgccac
ttcccgtgcgggaatgtcaactacggctaccagcagcagggcttgccgctcgaggccgcc
gctggcccgggggccggccgctacgaggacccgatgctgaaagccaagggtagcggcaag
cagcctgggccctga
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integrated database retrieval system