KEGG   Neogale vison (American mink): 122894485
Entry
122894485         CDS       T08764                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
nvs  Neogale vison (American mink)
Pathway
nvs00670  One carbon pool by folate
nvs01100  Metabolic pathways
nvs01240  Biosynthesis of cofactors
nvs04981  Folate transport and metabolism
Module
nvs_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    122894485 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    122894485 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nvs04147]
    122894485 (MTHFD1)
Enzymes [BR:nvs01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     122894485 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     122894485 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     122894485 (MTHFD1)
Exosome [BR:nvs04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   122894485 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH Herpes_PAP
Other DBs
NCBI-GeneID: 122894485
NCBI-ProteinID: XP_044088268
LinkDB
Position
13:complement(36346588..36403977)
AA seq 1040 aa
MKTQSERASSTSQSFPPATHHRVPSSFRGIELPYPRSSLHRPFRPSGLRTRIGGGAGAGW
EERRRKSSISWVVPKHVGWVVPRAGGASGSSVLVVSIVGSGLIKAMAPAEILNGKVVSAQ
IRERLKNQVSQMKEQVPGFTPGLAILQVGDRDDSNLYINVKLKAAEEIGIKATHIKLPRT
ATESEVLKYVTSLNEDLTVHGFIVQLPLDSENPINTEVVVNAIVPEKDVDGLTSISAGKL
ARGDLNDCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAPMHDLLLWNHATVTTC
HSKTANLGEEVNKGDILVVATGKPEMVKGEWIKPGAIVIDCGINYVPDDTKPNGKKVVGD
VAYSEARERAGFITPVPGGVGPMTVAMLMQSTVESAARFLEKFKPGKWRIQYNNLNLKVP
VPSDIDISRSCKPKPIGSLAREIGLLSEEVELYGETKAKVLLSALERLKHQPDGKYVVVT
GITPTPLGEGKSTTTIGLVQALGAHLFQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPM
EEFNLHLTGDIHAITAANNLVAAAIDARMFHEQTQTDKALFNRLVPSVNGVRKFSDIQIR
RLQRLGIEKTDPTTLTDDEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGH
TRTAQFDISVASEIMAVLALTSSLEDMRERLSRMVVASSKKGEPISTEDLGVSGALTVLM
KDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADI
GMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYTEENLELVEKGF
SNLRKQIENARMFGVPVVVAVNAFKTDSEAELDLVSRLAKEHGAFDAVKCTHWAEGGKGA
LALAQAVQRASQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQ
GFGDLPICMAKTHLSLSHNPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPT
RPCFYDIDLDPETEQVNGLF
NT seq 3123 nt   +upstreamnt  +downstreamnt
atgaagacgcaatccgaaagggcttcttccaccagccaatcatttccgccagccactcat
caccgagttccttcatctttccgcggcatcgaacttccatatccccgctcttcgctacat
aggcctttccgtccttccggactgcgcacgcgcatcggcgggggggcgggggcagggtgg
gaggagcgcaggcgcaaaagcagcatctcctgggtagtccctaaacacgtgggttgggtt
gtcccgcgcgccggtggagctagtggatcctcagttttggtggtgtccatcgtgggcagc
ggactaataaaggccatggcaccggcggaaatcctgaacgggaaggtggtctccgcgcaa
ataagggagagactgaagaaccaagtctctcagatgaaggagcaagttcctggttttaca
ccaggcctggcaattttacaggttggcgacagagatgattctaatctttatataaatgtg
aagctgaaggctgctgaagagattgggatcaaagccacacacattaagttaccaagaacg
gccacagaatctgaggtgctgaagtacgttacgtcactgaatgaagacctcactgtacat
ggtttcatagtacagctgcctttagattcagagaaccccattaacactgaagtggtggtc
aatgcgattgtacccgaaaaggatgtggatgggttaactagcatcagtgctggaaaactt
gctagaggtgacctaaatgactgtttcatcccatgtacgcctaaaggatgcttggaactc
atcaaggagacaggggtgcagatcgctggaaggcacgcggtcgtggtcgggcgcagtaag
atagtcggtgcccccatgcatgacttgcttctgtggaaccatgccacggtgaccacctgc
cactccaagactgccaatctaggcgaagaggtaaataaaggtgacatcctggtggttgca
actggtaagccggaaatggtaaaaggggagtggatcaaacctggggcaatagtcatcgac
tgcgggatcaattatgtccccgatgatacaaaaccaaatgggaaaaaagtggtgggtgat
gtggcctacagtgaggccagagagagggcaggcttcatcactccggttcctggaggcgtg
gggcccatgaccgtggcaatgctgatgcagagcacggtagagagcgcagcgcgtttcttg
gagaaatttaagccaggaaagtggaggattcagtataacaaccttaacctcaaggttcct
gttccaagtgacattgacatatcacgatcttgcaagccgaagcccattggcagccttgct
cgggaaattggtctgctgtctgaggaggtcgaattgtacggtgagacaaaggccaaggtt
ctgctgtccgcactggagcgcctgaagcaccagcctgacgggaaatacgtggtggtgact
gggatcaccccaacgcccctgggagaagggaagagcacaaccaccattgggctggtgcaa
gcccttggcgcccatctgtttcagaacgtctttgcatgtgtgcgacagccttctcagggc
cccacctttggaataaaaggtggcgctgcaggaggaggctactcccaggtcattcccatg
gaagagtttaatctccacctcaccggtgacatccacgccatcactgccgcgaataacctt
gtcgccgcggccatcgatgcccggatgttccatgaacagacgcagacagacaaggctctc
ttcaatcgtttggtgccttcagtaaatggagtgagaaagttctctgatattcagatccga
aggttacagagactaggcatcgaaaaaaccgaccctaccacactgacggatgacgagata
aacagatttgcaagattggacattgacccagaaaccataacttggcaaagagtattggat
accaacgatagattcttgagaaagatcaccatcggacaggctccaacggagaaagggcac
acacggacggcccagtttgatatctctgtggccagtgaaatcatggctgtgctggctctt
accagttcgctagaagacatgagagagagactgagcagaatggtggtggcatccagtaag
aaaggggagcccatcagtaccgaagatctgggggtgagcggtgcgttgacagtgctcatg
aaggatgcaatcaagcccaatctcatgcagacattagagggcactccagtatttgttcat
gctggaccgtttgccaacatcgcacatgggaattcctccatcattgcagaccggattgcc
ctcaagcttgttggccctgaagggtttgtggtgactgaagcaggatttggagcagacatt
ggaatggaaaagttctttaacatcaagtgccggtattctggtctccgccctcacgtggtg
gtgcttgtggccacagtcagggctcttaagatgcatggaggtggccccacggttactgcc
ggactgcctctccccaaggcttacacagaggagaacctggagctggttgagaaaggcttc
agtaacttaaggaaacaaatcgaaaatgccagaatgtttggagttccagtggtagtggcg
gtgaatgcattcaagaccgattcagaggccgagctggaccttgtcagccgccttgccaaa
gaacatggggcttttgatgctgtgaaatgcacacactgggcagaagggggcaagggtgcc
ttagccctagctcaggccgtccagagagcatctcaggcgcccagcagctttcagctcctt
tatgacctcaagctcccagtcgaggataaaatcagaatcattgcacagaagatctatggg
gctgacgacattgaattgcttcccgaagctcaacacaaagctgaagtctacacaaaacag
ggttttggggacctgcccatctgcatggccaaaacacacttgtccttgtctcataaccca
gagcagaagggtgtacccacgggctttgtcttgcccatccgtgacatccgcgccagcgtc
ggggccggttttctgtaccccttggtggggacgatgagcacaatgcctggactccccacg
cggccctgtttctatgatattgatttggatcccgaaactgaacaggtgaacgggttgttc
tag

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