KEGG   Nestor notabilis (Kea): 104408401
Entry
104408401         CDS       T08494                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
nnt  Nestor notabilis (Kea)
Pathway
nnt00670  One carbon pool by folate
nnt01100  Metabolic pathways
nnt01240  Biosynthesis of cofactors
nnt04981  Folate transport and metabolism
Module
nnt_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:nnt00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    104408401 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    104408401 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nnt04147]
    104408401 (MTHFD1)
Enzymes [BR:nnt01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     104408401 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     104408401 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     104408401 (MTHFD1)
Exosome [BR:nnt04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   104408401 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH DUF6507 OCD_Mu_crystall
Other DBs
NCBI-GeneID: 104408401
NCBI-ProteinID: XP_010016298
LinkDB
Position
Unknown
AA seq 892 aa
QVRERLKQQVVEMREKFPGFRPGLAILQVGNRDDSNLYINMKLKAAAEIGISANHIKLPN
TATEADVLKCIASLNGDPAVHGFIVQLPLDSDKPINTEKITNAVAPEKDVDGLSSINAGK
LSRGDLGDCFIPCTPKGCMELIRQTGIQVAGKRAVVVGRSKIVGAPMHDLLLWNHATVTT
CHSKTSTLADEVGKADILVVAAGKAEMVKGEWIKPGAIVIDCGINHVPDSTKASGKRVVG
DVAYSTAKEKASYITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQPGKWNIQYNQLTLKM
PVPSDIEISQSYIPKPIDQVAREVGLLPDEVELYGQTKAKVHLSALKRLKNQPDGKYIVV
TGITPTPLGEGKSTTTVGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYCQVIP
MEEFNLHLTGDIHAITAANNLVAAAVDARIFHELTQTDQALYKRLVPSDNGVRKFSDIQI
RRLQKLGINKTDPMALTKEEVNLFVRLDIDPGTITWQRVLDTNDRFLRKITIGQSPTEQG
FSRTAQFDITVSSEIMAVLALSDGLDDMKKRLGRMVVASNKKGEPVTTDDLGVTGALAVL
MKDAVKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGKDGFVVTEAGFGAD
IGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPAVTAGVPLPKEYMEENLQLLAKG
CSNLNKQIQNARMFGVPVVVAVNAFKTDTKAEMALVVQQAKEAGAFDAVVCTHWAEGGKG
AVALAQAVQRASQTPSNFRFLYDVKLPVIDKIRIIAQQIYGASDIELLPEAQEKVALYTK
QGFGNLPICMAKTHLSLSHDPEQKGAPTGFILPIRDIRASVGAGFLYPLVGT
NT seq 2677 nt   +upstreamnt  +downstreamnt
acaagtgagagagaggctaaagcagcaagttgttgagatgagagagaaatttccaggctt
cagaccaggacttgcgattttgcaggttggaaatcgggatgattcaaacctctacattaa
tatgaagctgaaggctgccgctgagattgggatcagtgcgaatcacataaaactgccaaa
cacagcaacagaagctgacgtcctcaagtgcattgcctctttgaatggagaccctgctgt
tcatggctttatagtgcagctgccacttgactctgataaacccatcaatacagaaaaaat
aaccaatgctgttgcacctgagaaggatgtagatggcttaagtagcatcaatgctgggaa
actctccagaggggaccttggagactgctttattccctgtacaccaaaaggatgcatgga
acttatcaggcagacaggcatccaggttgcagggaaaagggctgtagtggttggtcgcag
taagattgttggtgctcccatgcacgacctgctgctctggaatcacgcaaccgtaaccac
ttgccattcaaagacctcaacactggctgatgaggttggtaaagctgatatcctggtggt
tgcagctggtaaagctgaaatggtgaaaggtgaatggatcaaacctggtgcaattgtaat
tgactgtggaattaaccatgtgccggacagcacaaaggccagtggaaaaagagttgtagg
agatgtggcatacagcacagcaaaagagaaagcttcctacatcacacctgttcctggtgg
cgttgggcctatgactgtggccatgttaatgcagagcacagtggagagtgcacagcgttt
tctggagaagttccagcctggaaaatggaacatccagtataaccagcttaccctaaagat
gccagttccaagtgatattgaaatatcacagtcttacatacccaagcccattgatcaagt
tgcaagagaagttggcctgctccctgatgaggtggaactctatggccaaactaaagccaa
ggttcatctgtcagctctgaaacggttgaagaaccagccagatggcaaatacattgttgt
tactgggataactcctactcccctgggagaggggaaaagcaccaccactgtcggtcttgt
tcaagccttaggagcacaccttcaccagaatgtctttgcttgtgttcgtcagccttctca
ggggccaacctttggtataaaaggtggagctgcaggtggcggctattgtcaagtgatccc
catggaagagtttaaccttcacctcactggtgacatccatgctatcactgcagccaacaa
cctggttgctgctgctgtcgatgcacgtatattccatgagctcactcagactgaccaggc
tctctacaagcgtttggtgccttctgacaatggtgttaggaagttctcagacattcagat
ccgaagactacagaaattgggcattaacaaaactgatcctatggctttgacaaaggaaga
agtcaatttatttgtgagattggacattgacccaggcaccataacatggcaaagagtact
ggatacaaatgacaggttccttaggaaaatcactattggacagtctccaacagaacaagg
cttttcacggacggctcagtttgatatcacagtgagcagcgaaatcatggcagttctagc
actctctgatgggctggacgatatgaaaaagcgactgggaagaatggtggtggcttccaa
caagaaaggagaaccagttacaacagatgaccttggagtgactggtgctctggctgtctt
gatgaaagatgctgttaaaccaaacctcatgcagacactagagggaacaccggtgtttgt
tcatgctggaccttttgccaatattgcacatgggaattcttcagtgctggcagacaaaat
agcactgaagcttgtgggtaaagatggttttgttgttacagaagcaggatttggtgcaga
cataggcatggagaaattctttaatattaagtgccgctattccggtctccggcctcatgt
ggtggtgttggttgctactgtccgagctctcaaaatgcatggaggaggccctgcagttac
tgctggggtacctttaccaaaggagtacatggaagagaatcttcaactgttggcaaaagg
ctgtagtaatctaaacaagcaaatccaaaatgcacggatgtttggtgtcccagtagtagt
ggctgtaaatgctttcaaaacagatacaaaggctgaaatggcccttgtagtgcaacaggc
aaaggaagcaggagcatttgatgctgtggtgtgcactcattgggcagagggaggtaaagg
agcagttgcactggctcaagctgttcagagagcatcgcagacacccagcaacttcaggtt
cctctatgatgtgaagctccctgttatagataagatcaggattattgcacagcagatcta
tggggcaagtgacattgagctacttccagaagcacaggagaaggttgccttgtacactaa
gcaaggatttggaaacctgccaatctgcatggctaaaactcatttgtcattgtctcatga
ccctgaacaaaaaggagcacctacaggttttattctgccaatccgagacattcgggccag
tgttggtgctgggttcctgtatccactcgtaggaacg

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