KEGG   Nocardia huaxiensis: H0264_11945
Entry
H0264_11945       CDS       T07784                                 
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
nhu  Nocardia huaxiensis
Pathway
nhu00020  Citrate cycle (TCA cycle)
nhu00630  Glyoxylate and dicarboxylate metabolism
nhu00785  Lipoic acid metabolism
nhu01100  Metabolic pathways
nhu01110  Biosynthesis of secondary metabolites
nhu01120  Microbial metabolism in diverse environments
nhu01200  Carbon metabolism
nhu01210  2-Oxocarboxylic acid metabolism
Module
nhu_M00009  Citrate cycle (TCA cycle, Krebs cycle)
nhu_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:nhu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    H0264_11945
   00630 Glyoxylate and dicarboxylate metabolism
    H0264_11945
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    H0264_11945
Enzymes [BR:nhu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     H0264_11945
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     H0264_11945
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     H0264_11945
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     H0264_11945
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: QLY32856
UniProt: A0A7D6VM12
LinkDB
Position
complement(2671376..2675119)
AA seq 1247 aa
MRRTPAVSSSTDQFGQNQWLVDEMYQKYKQDPSSVDESWHEFLADYTPENTGDTGNSKPV
AASAPAAAPTAAPAPAPAPQPAAAPAPAPAAQQRAPQTTPAPTSNAAPTAGPKVAAEDEA
KVLRGPAAAIVKNMSASLTIPTATSVRAIPAKLMIDNRLVINNHLARTRGGKISFTHLLG
YAIVQAIKSFPNMNRHFAEVDGKPNAVTPAHTNLGLAIDLRAKDGSRTLAVAAIKNTEGM
TFAQFHSAYEDVVRRARDGKLTTEDFSGVTISLTNPGTIGTNHSVPRLMPGQGAIIGAGA
MEYPAEFQGMSDDQLAEIGIGKLMTLTSTYDHRIIQGAESGDFLRTIHQLLISDEFYDEI
FHGMGVPYEPVRWRKDIKERGVDKSVRVQELIAAYRNRGHLMADTDPLRLVKDKFRSHPD
LDVTSHGLTLWDLDREFNVAGFHGQERMKLRDVLSILRDAYCRHVGVEYTHILDPEQLQW
IQDRVEQKHAKPTVAEQKYIMSRLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDGVI
DQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSKIFTEFEGNMNPAATHGSGDVKYHLGA
RGTYIQMFGDNDIEVSLTANPSHLEAVDPVLEGLVRAKQDLLTKEDIVTKGEEARTFSVV
PLMLHGDAAFAGQGVVAETLNLSVLRGYRTGGTVHIVVNNQIGFTTAPEYSRSTEYSTDI
AKFIGAPVFHVNGDDPEACVWVAKLAVDYRQRFNRDVVIDMICYRRRGHNEGDDPSMTQP
HMYDVIDTKRSVRKAYTESLIGRGDISMKEAEDALRDYQGQLERIFNEVRELEKYSPEPS
ESVEDEQQLPANLVTSVDKTVLQRIGDAFVNAPEGFSVHPRVKPVMEKRREMAYEGKVDW
AMAELMAFGTLIDEGHAVRLTGQDSRRGTFSQRHSVIIDRKTGAEYTPLHNIGSKNPGWF
AVHDSALSEYAAVGFEYGYSLGNPDALVLWEAQFGDFVNGAQTIIDEFISSGEAKWGQLS
EVVLLLPHGHEGQGPDHTSGRIERFLQLCAEGSMTVSVPSTPSNYFHLLRRHALDGIRRP
LVVFTPKSMLRNKAVVSDIEDFTDNKFRTVLEEPTYESGDGDRSKVKRVLLTSGKIYYEL
AAEKNKQNRDDVAIVRVEQLYPIPKFRLNEALEGYANATDLVWVQEEPANQGAWPFFGLN
LPEILPARFNKLRRISRRAMSAPSSGSSKVHAVEQQEIIEEAFAPTA
NT seq 3744 nt   +upstreamnt  +downstreamnt
atgaggcgaacacctgctgtgagcagctcaacagaccagttcggacagaaccagtggctt
gtcgacgagatgtaccagaagtacaagcaagacccctcgtccgtcgatgagagctggcac
gagttccttgccgactacacgccggagaacaccggcgacaccggcaacagcaagccggta
gccgcctcagctcccgccgctgcgccgaccgcagcccccgccccggcccctgcgccgcag
cccgccgccgcgcccgccccggcaccggccgcgcagcagcgtgctccgcagaccaccccg
gcgccgacctccaacgcggcccccaccgcgggcccgaaggtcgccgccgaagacgaggcc
aaggtgctacgcgggccggcagcggccatcgtgaagaacatgtcggcgtcgctgaccatc
cccaccgccacctccgtgcgcgccattccggcgaagctgatgatcgacaaccgtctggtc
atcaacaatcacctcgcacgcacccgcggcggcaagatctccttcacccacctgctgggt
tacgccatcgtgcaggcgatcaagtcgttcccgaacatgaaccggcacttcgccgaggtc
gacggcaagcccaacgcggtcacccccgcgcacaccaatctgggcctggccatcgacctg
cgcgccaaggacggcagccgcaccctggccgtcgccgccatcaagaacaccgagggcatg
accttcgcgcagttccacagcgcgtacgaggacgtcgtgcgccgcgcgcgtgacggcaag
ctgaccaccgaggacttctccggcgtcaccatctcgctcaccaacccgggcaccatcggc
accaaccattcggtgccgcgtctgatgccgggccagggcgcgatcatcggcgcgggcgcc
atggagtacccggccgagttccagggcatgagcgacgatcagctcgccgagatcggcatc
ggcaagctcatgacgctcacctccacctacgaccaccgcatcattcagggtgcggagtcc
ggtgacttcctgcgcaccatccaccagctgctgatctccgacgagttctacgacgagatc
ttccacggcatgggtgttccttacgagccggtgcgctggcgcaaggacatcaaggagcgc
ggcgtcgacaagagcgtccgcgtgcaggagctcatcgcggcgtaccgcaaccgcggtcac
ctcatggccgacaccgacccgctgcggctggtgaaggacaagttccgctcgcacccggac
ctggatgtcacctcgcacggcctgaccctgtgggacctggaccgcgaattcaacgtggcg
ggcttccacggccaggagcgcatgaagctgcgcgacgtgctgtccatcctgcgcgacgcg
tactgccgccacgtgggtgtggagtacacccacatcctggatcccgaacagctgcagtgg
attcaggatcgcgtggagcagaagcacgcgaaaccgactgtggccgagcagaagtacatc
atgtcccggctcaatgcggccgaggcgttcgagaccttcctgcagaccaaatacgttggc
cagaagcgcttctcactcgaaggcgcggagtccgtcattccgatgatggacggcgtgatc
gaccagtgcgccgagcacgccctcgacgaggtcgtcatcggcatgccgcaccgcggccgc
ctgaacgtgctggcgaacatcgtcggcaagccctactcgaagatcttcaccgagttcgag
ggcaatatgaacccggccgccacgcacggctcgggcgacgtgaagtaccacctgggtgcg
cgcggcacctacatccagatgttcggcgacaacgacatcgaggtctcgctgacggccaac
ccgtcgcacctcgaggccgtcgacccggtgctggagggtctggttcgtgccaagcaggat
ctgctcaccaaggaagacatcgtcaccaagggcgaagaggcgcggaccttctcggtcgtg
cccctgatgctgcacggtgacgcggccttcgccggtcagggtgtcgtcgccgagacgctg
aacctgtcggtgctgcgcggctaccgcaccggtggcaccgtgcacatcgtggtgaacaac
cagatcggcttcaccaccgcaccggagtactcgcgttccaccgaatactccacggacatc
gcgaaattcatcggtgcgccggtgttccatgtcaacggcgacgacccggaagcctgtgtg
tgggtggccaagctggccgtcgactaccgccagcgcttcaaccgcgatgtcgtgatcgac
atgatctgctaccgccgtcgtggccacaacgagggcgacgacccgtcgatgacgcagccg
cacatgtacgacgtgatcgacaccaagcgttcggtgcgcaaggcgtacaccgagtcgctg
atcggtcgtggcgacatctccatgaaggaagccgaagacgccctgcgcgactaccagggt
cagctggagcggatcttcaacgaggtgcgcgagctggagaagtactcgccggagccgtcg
gaatcggtcgaggacgagcagcagctgcccgcgaatctcgttacctccgtggacaagacg
gttctgcagcggatcggcgacgcgttcgtcaacgcgccggagggcttctcggtgcacccg
cgcgtcaagccggtcatggagaagcgccgcgagatggcctacgagggcaaggtcgactgg
gccatggccgagctgatggccttcggcacgctgatcgacgaggggcacgcggtgcgtctc
accggtcaggactcgcgtcgtggcacgttctcgcagcgccactcggtcatcatcgaccgc
aagaccggtgccgagtacacgccgctgcacaacatcggctccaagaacccgggttggttc
gcggtgcacgactcggcgctgtccgagtacgcggccgtcggtttcgaatacggctactcg
ctgggcaacccggacgcactcgtgctgtgggaagcgcagttcggtgacttcgtcaacggc
gcgcagaccatcatcgacgagttcatctcctccggtgaggccaagtggggtcagctctcc
gaggtcgtgctgctgctgccgcacggtcacgagggccagggccccgaccacacctcgggt
cgtatcgagcggttcctgcagctgtgcgccgagggttcgatgacggtctcggtgccgtcc
accccgtcgaactacttccacctgctgcgccgccacgccctggacggcatccgccgcccg
ctggtggtcttcaccccgaagtccatgctgcgcaacaaggccgtggtctccgacatcgag
gacttcacggacaacaagttccgcaccgtcctggaggagcccacctacgagtcgggcgac
ggcgaccgttcgaaggtcaagcgcgttctcctcacctccggcaagatctactacgagctg
gcggccgagaagaacaagcagaaccgcgacgacgtggccatcgtccgcgtcgagcagctc
tacccgatcccgaagttccgcctgaacgaggccctcgaaggctacgccaacgccaccgat
ctggtgtgggtccaggaagaacccgccaaccagggcgcgtggccgttcttcggcctcaac
ctcccggagatcctcccggcccgcttcaacaagctgcgccgcatctcccgccgcgccatg
tcggccccgtcctcgggttcgtccaaggtgcacgcggtggaacagcaggagatcatcgag
gaagccttcgcgccgacggcgtaa

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