KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112408305
Entry
112408305         CDS       T08872                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00240  Pyrimidine metabolism
nasi00670  One carbon pool by folate
nasi01100  Metabolic pathways
nasi01232  Nucleotide metabolism
nasi01523  Antifolate resistance
nasi04981  Folate transport and metabolism
Module
nasi_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    112408305 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    112408305 (TYMS)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    112408305 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    112408305 (TYMS)
Enzymes [BR:nasi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     112408305 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 112408305
NCBI-ProteinID: XP_024613677
UniProt: A0A341CIB3
LinkDB
Position
Unknown
AA seq 323 aa
MPAAGSELPRPMSPPAAQEQGAESRPPPPHGELQYLGQIEHILRCGFRKDDRTGTGTLKL
DGMFCFPILKLYNKLCFPDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWD
ANGSRDFLDSLGFSTRAEGDLGPVYGFQWRHFGAEYKEMDSDYSDQGVDQLQKVIDTIKT
NPDDRRIILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASY
ALLTYMIAHITGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRAFPKLKILRKVEKIDD
FKAEDFQIEGYNPHPTIKMEMAV
NT seq 972 nt   +upstreamnt  +downstreamnt
atgcccgccgccggctcagagcttccgcgcccgatgtcgccgcctgccgcgcaggagcag
ggcgccgagtcgcggccgccgccgccgcacggggagctgcagtacttggggcagatcgag
cacatcctccgctgcggctttcggaaggatgaccgcacgggcaccggcaccctaaagttg
gatggcatgttctgttttcccatcttgaaattatacaataaactttgttttccagatgaa
tttcctctgctgacaaccaaacgtgttttctggaagggtgttttggaggagttgctgtgg
tttatcaagggatccacaaacgctaaggagctgtcttccaagggagtgaaaatctgggat
gcaaatgggtcccgagacttcttggacagcctgggattctccaccagagcagaaggggat
ttaggcccagtttatggctttcagtggaggcattttggggctgaatacaaagagatggat
tcagattattcagatcaaggagtagatcaactgcaaaaagtgattgacacaatcaaaacc
aaccctgacgacagaagaatcatcctgtgtgcttggaatccaaaagatctccctctcatg
gccctacccccgtgccatgccctttgccagttctacgtagtgaacggtgagctgtcctgc
cagctgtaccagaggtcaggagacatgggcctgggtgtgcccttcaacatcgccagctac
gccctgctcacctacatgatcgcacacatcacgggcctgaagccaggtgactttgtacac
actttgggagatgcacacatttacctgaatcacattgagccgctgaaaattcagctccag
cgagaaccaagggctttccccaagctcaaaatccttcgaaaagttgagaaaattgatgac
ttcaaggctgaagactttcagattgaaggctacaatcctcacccgaccattaaaatggaa
atggctgtatag

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