KEGG   Mustela nigripes (black-footed ferret): 132003839
Entry
132003839         CDS       T09425                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp00061  Fatty acid biosynthesis
mnp00620  Pyruvate metabolism
mnp00640  Propanoate metabolism
mnp01100  Metabolic pathways
mnp01212  Fatty acid metabolism
mnp04152  AMPK signaling pathway
mnp04910  Insulin signaling pathway
mnp04922  Glucagon signaling pathway
mnp04936  Alcoholic liver disease
Module
mnp_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    132003839 (ACACA)
   00640 Propanoate metabolism
    132003839 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    132003839 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    132003839 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    132003839 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    132003839 (ACACA)
   04922 Glucagon signaling pathway
    132003839 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132003839 (ACACA)
Enzymes [BR:mnp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     132003839 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     132003839 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     132003839 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 132003839
NCBI-ProteinID: XP_059235627
LinkDB
Position
16:complement(36012188..36297098)
AA seq 2383 aa
MWWSTLMSILRASSFWRWISAQTVRIIRALRAHFEGIMDEPSPLGKPMELNQHSRFIIGS
VSEDNSEDEISSLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHMRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYGGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVK
RPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRD
EPIHILNVAIKTDCDIEDDGLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCE
VDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQAFLPSPPLPSDMLTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRAS
ELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSA
LNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHN
IVCDDFEGVFTVLHWLSYMPKNVRSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPH
PTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPAN
LDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKF
GAYIVDSLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGT
VEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSPAERKELENKLKEREEFLIPIYHQVA
VQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQ
IQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQ
IRSLVQANPEVAMDSIVHMTQHISPTQRAEIVRILSTMDSPST
NT seq 7152 nt   +upstreamnt  +downstreamnt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcagacagtaagaattataagagctctgagagctcattttgaaggaataatggatgaa
ccatcccccttgggcaaacctatggagctgaaccagcattcccgattcataattggttct
gtgtctgaagataactcagaggatgaaattagtagcctggtgaagctggatctgctggag
gagaaggagggctctctatcaccagcttctgttggctcagatacactctctgatttgggg
atctccagcctacaggacggcttggctttacacatgaggtccagcatgtctggcttgcat
ctagtaaagcaaggtcgagaccgaaagaaaatagactctcagcgagatttcactgtagct
tctccagcagaatttgttacccgttttggggggaataaagtgattgagaaggttcttatc
gccaacaatggcattgcagcagtgaaatgcatgaggtctatccgccgatggtcttatgag
atgtttcgaaatgaacgtgcaatccgatttgttgttatggtaacacctgaagacctgaaa
gccaatgcagaatatattaagatggcagatcactatgtaccggtgccaggaggaccaaac
aacaacaactatgcaaatgtggaattaattcttgatattgccaaaaggattccagtacaa
gcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaacttcttttg
aaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttgggggataag
attgcatcttccatagtggctcaaactgcaggtatcccgactcttccctggagtggcagt
ggtcttcgtgtggactggcatgaaaatgatttttcaaaacgtatcttaaatgttccccag
gaattatatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggcagcagaggaa
gttggatatccagtgatgatcaaagcctcagaaggaggaggtgggaaaggaatcagaaaa
gtcaacaatgcagatgacttccccaacctcttcagacaggttcaagctgaagtccctggg
tctcctatatttgtgatgagactagccaaacagtctcgtcatctggaggtacagatccta
gcagatcaatatggcaatgctatctctctctttggccgtgactgctctgtacagcgcagg
catcagaagattattgaggaagcacctgctgctattgctactccagcagtatttgaacat
atggaacagtgtgcagtgaaacttgccaaaatggttggttatgtgagtgctgggactgtg
gaatacctctacagccaggatggaagcttctactttctggagctgaaccctcggctgcag
gtggagcatccttgtacagagatggtggctgatgtcaacctccccgcagcacaactccag
attgctatggggatccctctatacagaatcaaggatattcgtatgatgtatggggtatct
ccctggggcgatgctcccattgattttgaaaattctgctcacgttccttgtccaaggggc
catgttattgctgctcggatcaccagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaggaactgaatttccgtagcaataagaacgtttggggttatttcagtgtt
gctgctgcagggggccttcatgaatttgctgattctcagtttggtcactgcttctcctgg
ggagaaaacagagaggaagcgatttcaaacatggtggtggctttgaaggagctatctatt
cggggcgactttcgaactacagttgaatacctcatcaaattgttggagactgaaagcttt
cagctgaatagaatagacactggctggctggacagactgatagcagagaaagtacaggca
gagcgacctgacaccatgttgggagttgtatgtggggctctccacgtggcagatgtgagc
ctgcggaatagcatctccaacttccttcactccttagaaaggggtcaagtccttcctgcg
catacgcttctgaatacagtagatgttgaacttatctatgggggagtcaaatatgtactt
aaggtgacgcggcagtcccctaactcctatgtggtgatcatgaatggttcgtgtgtagaa
gtagatgtgcatcggctgagtgatggagggctgctcctgtcctatgatggcagcagttat
accacgtacatgaaggaggaagtggataggtatcgcatcacaatcggcaataagacctgt
gtgtttgagaaggaaaatgacccttctgtgttgcgctcgccttctgctgggaaattaatc
cagtacattgtggaagatggaggccatgtgtttgctggccagtgctatgctgagattgag
gtgatgaagatggtaatgaccttaacagctgcagagtctggttgtatccattatgtcaaa
cggcctggagcagctcttgaccctggctgcgtaatagccaaaatgcagttggacaacccc
agcaaagtccaacaggctgagcttcacacgggtagtctaccacggatccagagcacggcc
ctcagaggcgagaagctccatcgagtgttccactatgtcctggataatctggtcaacgta
atgaatggatactgccttccagatcctttttttagcagcagggtaaaagactgggtagag
cggttgatgaagaccctcagagatccctccttgcccctcctagaattgcaagatatcatg
accagtgtctctggccgtattccccccaacgtggagaagtctatcaagaaggaaatggct
cagtacgctagcaacatcacatcagtcctctgtcagtttcccagccagcagattgccaac
atcctagatagccatgcagctacattgaaccggaaatctgagcgggaagtcttcttcatg
aacacccagagcattgtccagctggtacagaggtaccgaagtggcatccgaggccacatg
aaggctgtggtgatggatctgctgcggcagtatctgcgagtagagacccagttccagaac
ggtcactacgacaaatgtgtgttcgcccttcgagaagagaacaagagtgacatgaacact
gtactgaactatatcttctctcatgcccaagtcaccaagaagaatcttctggtcacaatg
cttatcgaccagttgtgcggtcgggaccctactctcaccgatgagctgctaaatatcctt
acagagctcactcaactcagtaagaccaccaacgccaaagtggcacttcgagcacgccag
gttcttattgcctcccatttgccgtcatatgagcttcgccataaccaagtagagtccatc
ttcctttcagcaattgacatgtacggacatcagttttgcattgagaacttacagaaactc
atcttgtctgaaacgtctatttttgacgtcctaccaaacttcttctaccacagcaaccag
gtagtgaggatggcagctctggaggtttatgttcgaagggcttatattgcctatgaactt
aacagtgtacagcatcgccagcttaaggacaacacctgtgtggtggaatttcagttcatg
ctgcccacatctcatccaaacagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactatggcatgactcacgtagctagtgtcagcgatgtgctcttggat
aactcattcactccaccatgtcagcggatgggcggaatggtctcttttcggactttcgaa
gattttgtcaggatctttgatgaagtgatgggctgcttctgtgattctccaccccaaagc
cccacgttccctgaggcaggtcacacgtctctgtatgatgaggacaaggtccctagggat
gaaccaattcacattctgaatgtggctatcaagactgactgtgatattgaggatgatgga
ctggcagctatgttcagagagtttacccaacaaaacaaagctaccctggttgagcatggg
atacggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtcaactgtgag
gtggatcagagatttcatagagaatttcctaaatttttcaccttccgagcaagggataag
tttgaggaggatcgtatctatcgtcacctggagcctgccctagctttccagttagagctg
aaccggatgagaaattttgaccttactgccattccatgtgcgaatcacaagatgcacctg
tatcttggggcagccaaggtggaagtgggcacagaagtgacagactacaggttcttcgtg
cgtgcaatcatcagacattctgatctagtcaccaaggaagcttcttttgaatatctacaa
aatgaaggggagaggctgctcctagaagccatggatgagttggaagttgcttttaataat
acaaatgttcgcactgactgcaaccacatcttcctcaactttgtgcccacagtcatcatg
gacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatggaagtcggctg
tggaaattacgtgtcctccaggcagaactgaaaatcaacattcgcctgacgccaactgga
aaagcaattcccatccgcctcttcctgaccaacgagtctggctattacttggacatcagt
ttgtataaagaggtgactgactccaggacagcacagatcatgtttcaggcatatggagat
aaacagggaccattgcatggaatgctaatcaacactccatatgtcaccaaagacctgctt
caatcaaagagattccaggcacaatccttggggacaacatacatatatgatatcccagag
atgtttcggcagtctctgatcaaactctgggagtctatgtcctctcaggcattccttcca
tcaccacccctgccttctgatatgctgacatatacggagctcgtgttggatgatcaaggt
cagctggtccacatgaacaggcttccaggaggaaatgagattggcatggtagcttggaaa
atgacccttaaaagtcctgaatacccagaaggccgagatatcattgttattggcaatgac
atcacataccgaattgggtccttcgggccccaggaggatttgctctttctccgagcttct
gagcttgccagggccgagggtatcccacgcatctttgtggcagccaacagtggagcaaga
attggactggcagaggaaattcgtcatatgtttcatgtggcctgggtagatcctgaggat
ccttacaagggatacaaatatttatatctgacccctcaggattataagagagtcagtgct
ctcaactctgtccactgtgagcatgtagaggacgaaggagaatccaggtacaagataact
gatattattgggaaggaagagggacttggagcagagaatcttcggggctctggaatgatt
gctggagaatcctcattggcctatgatgagattatcaccatcagcctggttacatgccgg
gccattgggattggggcttaccttgtccggctgggacagagaaccatccaggttgaaaat
tctcacttaattctgaccggagctggggccctcaacaaagtccttgggcgggaagtatac
acctccaataaccaacttgggggcatccagattatgcacaacaatggggtgacccacaac
atcgtttgcgatgactttgaaggggttttcactgtcctgcactggctgtcttatatgccc
aagaatgtgcgcagttcagttcctctcttgaactccaaggatcctatagatagaatcatc
gagtttgttcccacgaaggccccatatgatcctcgatggatgctagcaggccgacctcac
ccaacccagaaaggtcagtggttgagtggattttttgactatggatctttctcggagatc
atgcaaccctgggcccagactgtggtggttggcagagccaggctaggaggaatacctgtg
ggagtagttgccgtagaaacccgaacagtggaactaagtatccccgccgatcctgcaaac
ctggattctgaagccaagataatccagcaggctggccaggtttggttcccagactctgcg
tttaagacctatcaggctatcaaggacttcaaccgtgaagggctgcctctgatggtcttt
gccaactggagaggcttctctggtggaatgaaagatatgtacgatcaagtgctaaagttc
ggtgcttacatcgtggatagcttacgggagtgctcccagccagtgatggtgtacattcct
ccccaggctgagctccgggggggctcctgggttgtgatcgaccccaccatcaacccccgg
cacatggaaatgtacgctgaccgagagagcaggggatcagttctggagccagaggggaca
gtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggacccagtc
tacattcgcttggctgagcgattgggcaccccagagctcagcccagcagagcggaaggag
ctggaaaacaagctgaaggagcgggaggaattcctaattcccatttaccatcaggtagcc
gtgcagtttgctgacttgcacgacacaccgggccggatgcaggagaagggtgttattaac
gatatcctggactggaaaacatcccggactttcttctactggcgactgaggcgtctcctg
ctggaggacctggtcaaaaagaaaatccacaatgccaacccagagctgaccgatggtcag
atccaggccatgttacggcgctggtttgtggaggtggagggaactgtgaaggcctatgtg
tgggacaataacaaggatctggtggagtggctggagaaacagctgaccgaggaagacggc
gttcgctcagtaatcgaggagaacatcaaatacatcagcagagactatgtcctcaagcag
atccgcagcttggtgcaggccaatcccgaggttgccatggactccatcgtccacatgact
cagcacatctcacccacacagcgagcagaaatcgtgcggatcctctccacgatggactcc
ccttcaacgtag

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