Miniopterus natalensis (Natal long-fingered bat): 107532934
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Entry
107532934 CDS
T05883
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mna
Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna00140
Steroid hormone biosynthesis
mna00980
Metabolism of xenobiotics by cytochrome P450
mna01100
Metabolic pathways
mna05204
Chemical carcinogenesis - DNA adducts
Module
mna_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mna00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
107532934 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
107532934 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
107532934 (HSD11B1)
Enzymes [BR:
mna01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
107532934 (HSD11B1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
Pyr_redox_2
DUF1776
Shikimate_DH
2-Hacid_dh_C
3HCDH_N
Pyr_redox_3
Motif
Other DBs
NCBI-GeneID:
107532934
NCBI-ProteinID:
XP_016062954
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All DBs
Position
Unknown
AA seq
292 aa
AA seq
DB search
MAFMKNYLLPILGIFLAYYYYSADEEFRPEMLKGKKVIVTGASMGIGKEIAYHLAKMGAH
VVVTARSEEALKKVVSDCLEYGAASAHYIAGTMENITFAEQFVAKAGKIMGGLDMLILNH
IAKVTMEPFAGGTYLTRTVMEVNYISYVALSMAAVPMLKQSNGSIVVVSSVAGKMASPLL
ASYSASKFALDGFFSSLRKEYLMTKINVSVTLCILGLINTDSAMKGISGILKAEASPKED
CALEIIKGGALRQEEVYYGKFLWPSFLLRNPGRGIVEFLSLRKYNVEKFINN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaactatctcctccccattctggggatcttcttggcctactactac
tattctgcggatgaggaattcagaccagagatgctaaaaggaaagaaagtgattgtcacg
ggggccagcatggggatcggaaaagagatcgcctatcatctggcgaagatgggagcccat
gtggtggtgacagcgaggtcagaagaagctctgaagaaggtagtatctgattgcctggag
tacggagcagcctcagcacactacattgctggcaccatggagaacataactttcgcggag
caatttgttgccaaagctggaaaaatcatgggggggctagacatgctcattctcaatcac
atcgccaaagtcactatggaaccgtttgctggtggcacgtacttaacgcgcacagttatg
gaggtcaactacatcagctatgtggccttgagtatggctgcagtccccatgctgaagcag
agcaatggaagcattgtcgtcgtctcctcagtggctgggaaaatggcgagtccacttctt
gcttcctactctgcaagcaagtttgctctcgatgggtttttctcctccctcaggaaggaa
tacttaatgaccaagatcaatgtgtcagtcaccctctgtatcctcggtctcataaacaca
gactcagccatgaaggggatttctgggatactcaaagcagaagcatctccaaaggaagac
tgtgccctggagatcatcaaagggggagctctgcgccaagaggaagtgtattatggcaaa
tttctgtggccctctttcctgctcagaaatccaggaaggggcatcgtcgaatttctcagc
ctaagaaaatataatgtggaaaaatttataaacaactag
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