KEGG   Marmota marmota marmota (Alpine marmot): 107148422
Entry
107148422         CDS       T09644                                 
Symbol
Idh2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
  KO
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma00020  Citrate cycle (TCA cycle)
mmma00480  Glutathione metabolism
mmma01100  Metabolic pathways
mmma01200  Carbon metabolism
mmma01210  2-Oxocarboxylic acid metabolism
mmma01230  Biosynthesis of amino acids
mmma04146  Peroxisome
mmma05230  Central carbon metabolism in cancer
Module
mmma_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mmma_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    107148422 (Idh2)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    107148422 (Idh2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    107148422 (Idh2)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    107148422 (Idh2)
Enzymes [BR:mmma01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.42  isocitrate dehydrogenase (NADP+)
     107148422 (Idh2)
SSDB
Motif
Pfam: Iso_dh
Other DBs
NCBI-GeneID: 107148422
NCBI-ProteinID: XP_015348550
Ensembl: ENSMMMG00000019823
UniProt: A0AAJ7AUX1
LinkDB
Position
Unknown
AA seq 400 aa
MDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVK
CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR
HAHGDQYKATDFVVDRAGTFKMVFTPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFA
HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD
MVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVT
RHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGTQDLIRFAQTLEKVCVETVESGAMT
KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKTNLDRALGKQ
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggatggtgatgagatgactcgcatcatctggcagttcattaaagagaagcttatcctg
cctcatgtggacgtccagctcaagtattttgacctcgggcttccaaatcgtgaccagact
gatgaccaggtcaccattgactccgcgttggccacccagaaatatagtgtggctgtcaag
tgtgccaccatcacccctgatgaggcccgtgtggaagagttcaagctgaaaaagatgtgg
aagagtcccaatggaaccatccggaatatcctcggtgggactgtcttccgagagcccatc
atttgcaaaaatatcccccgtcttgtccctggctggaccaagcccatcaccattggcagg
catgctcatggtgaccagtacaaagccacagactttgtggtagaccgagctggcacattc
aagatggtcttcactccaaaggatggcagtggagccaaggagtgggaggtgtacaacttc
cctgcgggcggcgtaggcatgggcatgtacaataccgatgagtccatctcgggttttgcg
cacagctgctttcagtatgcaatccagaagaaatggccgttgtacatgagcaccaagaac
accatcctgaaggcgtatgatgggcgtttcaaggacatcttccaggagatctttgacaag
cactataagactgattttgacaagaataagatctggtatgagcaccggctcatcgacgac
atggtggcccaggtcctcaagtcttcaggtggctttgtgtgggcctgcaagaactatgat
ggggacgtgcagtcggacatcctggcccagggctttggctccctcggcctgatgacgtcc
gtgcttgtttgccccgatgggaagaccattgaggctgaagctgctcatgggacagtcacc
cgtcattatcgggagcaccagaaaggccggccgaccagtaccaaccctatcgccagcatc
tttgcctggacgcggggcctggaacaccggggaaagttggatgggacccaggatctcatc
aggtttgcacagactctggagaaggtgtgcgtggagaccgtggagagtggcgccatgacc
aaggacctggccggctgcatccatggccttagcaatgtgaagctgaatgaacacttccta
aacaccacagacttcctggacaccatcaagaccaacttggacagagctctgggcaagcag
tag

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