KEGG   Mycobacterium lacus: MLAC_08740
Entry
MLAC_08740        CDS       T07377                                 
Symbol
kgd
Name
(GenBank) multifunctional 2-oxoglutarate metabolism enzyme
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
mlj  Mycobacterium lacus
Pathway
mlj00020  Citrate cycle (TCA cycle)
mlj00630  Glyoxylate and dicarboxylate metabolism
mlj00785  Lipoic acid metabolism
mlj01100  Metabolic pathways
mlj01110  Biosynthesis of secondary metabolites
mlj01120  Microbial metabolism in diverse environments
mlj01200  Carbon metabolism
mlj01210  2-Oxocarboxylic acid metabolism
Module
mlj_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mlj_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:mlj00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    MLAC_08740 (kgd)
   00630 Glyoxylate and dicarboxylate metabolism
    MLAC_08740 (kgd)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    MLAC_08740 (kgd)
Enzymes [BR:mlj01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     MLAC_08740 (kgd)
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     MLAC_08740 (kgd)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     MLAC_08740 (kgd)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     MLAC_08740 (kgd)
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh Transket_pyr OxoGdeHyase_C 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: BBX95580
UniProt: A0A7I7NG99
LinkDB
Position
complement(910885..914568)
AA seq 1227 aa
MYRKFRDDPSSVDPSWHEFLVDYNPESVSEPAPAPAPAAATPADGQAAAVAPEAKPTAPA
PQAAPPTPPVGTATVGDGAPTTLAAPPAKAAPPPPAEGDELQVLRGAAAAVVKNMSASLE
VPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKRFPNMNRHYTE
VDGKPTAVTPAHINLGLAIDLPGKDGKRSLVVAGIKGCETMRFAQFVTAYEDIVRRARDG
KLTAEDFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASEERIAELG
IGKLITLTSTYDHRIIQGAESGDFLRAIHEMLLSDAFWDEIFRELSIPYLPVRWSTDNPD
SIVDKNARVMELIAAYRNRGHLMADTDPLRLDKTRFRSHPDLEVLTHGLTLWDLDRVFKV
NGFAGCEYKKLRDVLGLLRDAYCRHIGVEYTHILDPEQQEWLQQRVETKHVKPTVAQQKY
ILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRG
RLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTA
NPSHLEAVDPVLEGLVRAKQDLLDHGSTDSEGQRAFSVVPLMLHGDAAFAGQGVVAETLN
LTNLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAKMIGAPIFHVNGDDPEACVW
VARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALI
GRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGAQPSESVESDQMIPAGLATAVDKSL
LARIGDAFLALPDGFTPHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAEGKLVRLS
GQDTRRGTFSQRHSVLIDRHTGEEFTPLQLLATNKDGTPTGGKFLVYDSPLSEYAAVGFE
YGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSTVVLLLPHGHEGQGPD
HTSGRIERFLQLWAEGSMTIAVPSTPSNYFHLLRRHALDGIMRPLIVFTPKSMLRNKAAV
SDIKDFTEIKFRSVLEEPTYEDGIGDRGKVTRILLTCGKLYYELAARKAKDKRDDIAIVR
IEQLAPLPRRRLGETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPRLGGIKRISR
RAMSAPSSGSSKVHAVEQQEILDEAFA
NT seq 3684 nt   +upstreamnt  +downstreamnt
atgtaccgcaagttccgcgacgacccctcctcggtcgatccgagctggcacgaattcctg
gtggactacaaccccgaatcggtctccgagccagcccctgcgcccgcccccgccgctgcg
acccccgccgacgggcaggcggccgcggtcgccccggaagcgaagccgaccgccccagca
ccacaggccgcgccgccgactccacccgtcggcaccgccacggtgggcgacggcgcgccg
accacgcttgccgcgccgccggcaaaagccgcccctcccccaccggccgaaggtgacgaa
ctgcaggtgctgcgcggcgcggcggcggccgtcgtcaagaacatgtcggcatcgctcgag
gtgccgacggcgaccagcgtccgggccgttccggccaagctgctgatcgacaaccggatc
gtcatcaacaaccagctcaagcgcacccgcggcggcaagatctcgttcacccatctgctc
ggctacgcgctggtgcaggcggtcaagcgtttcccgaacatgaaccggcactacaccgag
gtcgacggcaagcccaccgccgtcacacccgcgcacatcaatctgggcctggccatcgac
ctgccgggcaaggacggcaagcgctcactggtggtggccggcatcaagggctgcgagacc
atgcgatttgcgcagttcgtcaccgcctacgaagacatcgtgcgccgggcgcgcgacggt
aagctgaccgccgaagactttgccggcgtgacgatttcgctgaccaaccccggaaccatc
ggcaccgtgcactcggtgccgcggctgatggccggccagggcgcgatcatcggcgtcggc
gcgatggagtaccccgccgaatttcagggcgccagcgaggagcgcatcgccgaactgggc
atcggcaagctgatcaccctgacctcgacctacgaccaccgcatcatccagggcgcggaa
tccggtgacttccttcgcgccatccacgagatgctgctctcggacgcattctgggacgag
atcttccgcgagctgagtatcccgtacctgccggtgcgctggagcaccgacaacccggac
tcgatcgtcgacaagaacgcccgggtgatggagctgattgcggcgtaccgcaaccgcggc
cacctgatggccgacaccgacccgctgcggttggacaagacccgcttccgcagccatccc
gatctcgaagtgctgacccacggcctgacgctgtgggatctcgatcgggtgttcaaggtc
aacggcttcgccggttgcgagtacaagaagctgcgcgacgtcctgggcttgctgcgcgac
gcgtactgccgccacatcggggtggagtacacccacatcctcgaccccgaacaacaggag
tggctgcaacaacgggtcgagaccaaacacgtcaaaccgactgtcgcccaacagaagtac
atcctgagcaagctgaacgccgccgaggccttcgaaacgttcctgcaaaccaaatacgtt
gggcagaaacggttctcgctggaaggcgcggaaagcgtgatcccgatgatggacgcggcg
atcgaccagtgtgccgagcacggcctcgatgaagtggtgatcgggatgccgcaccgcggc
cggctcaacgtgctggccaacatcgtcggcaagccgtactcgcagatcttcaccgagttc
gaaggcaacctgaacccgtcacaagcgcacggctccggcgacgtgaaataccacctcggc
gccaccggtgtgtacctacagatgtttggcgacaacgacattcaggtgtcactgaccgcc
aacccgtcccacctagaggccgtcgacccggtgctcgaggggctggtgcgggccaagcag
gatctgctcgaccacggcagcaccgacagcgaagggcaacgcgcgttttcggtggtgccg
ttgatgctgcacggggacgccgccttcgccggccagggcgtggtcgccgagacgctgaac
ctgacgaacctgcccggctaccgcgtgggcggcaccatccacatcatcgtcaacaaccag
atcgggttcaccaccgcgccggagcattcgcggtccagcgagtactgcaccgacgtcgcg
aaaatgattggggcgccgatcttccacgtcaacggcgacgaccccgaggcgtgcgtgtgg
gtggcacggctggccgtggacttccggcagcggttcaaaaaggacgtcgttatcgacatg
ctgtgctaccgacgccgcgggcacaacgagggcgacgacccgtcgatgaccaacccctac
atgtacgacgtcgtcgacaccaagcgcggggcccgcaagagctacaccgaagccctcatc
ggccgtggcgacatctcgatgaaggaggccgaggacgcgctgcgcgactaccagggccag
ctggagcgggtgttcaacgaggtccgtgagctggagaagcacggcgcgcaacccagcgaa
tcggtggagtccgaccagatgatccccgcggggctggcgaccgcggtggacaaatcgctg
ctggcccggatcggcgacgcgttcctggccttgccggacggattcaccccgcacccacgc
gtccagccggtactggagaagcgccgggagatggcctacgagggcaagatcgactgggcc
ttcgccgagctgctggccctgggttcgctggtggccgagggcaagctagtgcggctatcc
ggccaagacacccgccgcggcaccttctcccagcggcattcggtgctcatcgaccgccac
accggtgaggagttcacgccgctgcagctgctggcgaccaacaaggacggcactcccacg
ggcggcaagttcctggtgtacgactcgccgctgtccgagtacgccgcggtcggcttcgag
tacggctacaccgtgggcaacccggacgccgtcgtcctgtgggaggcgcagttcggcgac
ttcgtcaacggcgcgcagtcgatcatcgacgaattcatcagctccggtgaggccaaatgg
ggccagctgtccacggtcgtgctgctgctgccacacggacacgaggggcaggggcctgac
cacacctccggacgcatcgagcgcttcctacagctgtgggcggagggttcgatgacgatt
gcggtgccgtcgacaccgtccaactacttccacctgttgcgccggcacgcgctcgacggg
atcatgcgcccgctcatcgtgttcacgccgaagtcgatgctgcgcaacaaggcagcggtc
agcgacatcaaggacttcaccgagatcaaattccgctcggtgctcgaggagccgacctac
gaggacggcatcggcgatcgcggcaaggtcacccggatcctgctgacctgcggcaagctc
tactacgagctggccgcgcgcaaggccaaggacaagcgcgacgacatcgcgatcgtgcga
atcgaacaacttgccccgctgcccaggcgccggctgggcgagacgctggaccgctacgag
aacgtcaaggagttcttctgggtgcaggaagagccggccaaccagggcgcgtggccgcgg
ttcggcctggagctgcccgagctgctgccgaggctgggcggcatcaagcgcatttcgcgc
cgggccatgtcggcaccgtcgtcgggctcgtcgaaggtgcacgcggtcgagcaacaggag
atcctcgatgaggcgttcgcctga

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