KEGG   Mycobacterium sp. JLS: Mjls_3987
Entry
Mjls_3987         CDS       T00482                                 
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
mjl  Mycobacterium sp. JLS
Pathway
mjl00020  Citrate cycle (TCA cycle)
mjl00630  Glyoxylate and dicarboxylate metabolism
mjl00785  Lipoic acid metabolism
mjl01100  Metabolic pathways
mjl01110  Biosynthesis of secondary metabolites
mjl01120  Microbial metabolism in diverse environments
mjl01200  Carbon metabolism
mjl01210  2-Oxocarboxylic acid metabolism
Module
mjl_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mjl_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:mjl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    Mjls_3987
   00630 Glyoxylate and dicarboxylate metabolism
    Mjls_3987
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Mjls_3987
Enzymes [BR:mjl01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     Mjls_3987
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     Mjls_3987
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     Mjls_3987
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     Mjls_3987
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: ABN99762
UniProt: A3Q3N5
LinkDB
Position
4217586..4221380
AA seq 1264 aa
MSSSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYNPEPTTDSSASENGQQTRTA
APKAPPEPAPAPAPKSQDSKSQAPKQDSKPQESKPQAKAKPAESKSSTKPADAKSEKSGK
SGTNGAAKPAAQPADDSDQNQVLRGAAAAVAKNMSASLDVPTATSVRAIPAKLMIDNRVV
INNHLKRTRGGKISFTHLIGYAIVAAVKKFPNMNRHFAEVDGKPNAVTPAHTNLGLAIDL
QGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIG
TVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAES
GDFLRTVHQLLLSDDFFDEIFRELGIPYEPVRWRTDNPDSIEDKNARVIELIAAYRNRGH
LMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREFKVNGFAGAERKKLRDVLAVLRDA
YCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQTKYVG
QKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFE
GNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLVRAKQD
LLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQIGFTT
SPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDLLCYRR
RGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLEQVF
NEVRELEKHEIEPSESVEADQQIPAKLATAVDKSLLARIGDAHLAVPEGFTVHPRVKPVL
EKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRKTGKEF
TPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFINGA
QSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPST
PANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGDG
DRNKVTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYPNVDEK
FWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQEILDE
AFAP
NT seq 3795 nt   +upstreamnt  +downstreamnt
gtgagcagttcaccttcaccattcggccagaacgaatggttggtcgaggagatgtatcgc
aaattccgcgaggatccctcgtcggtagaccccagttggcacgagttcctcgtcgactac
aacccggaacccaccaccgactccagcgcgagcgagaacggtcagcagacgcgcaccgcg
gcgcccaaggccccgccggagccggcgcccgccccggcgccgaaatcccaggactcgaag
tcgcaggcccccaagcaggattcgaagccgcaggagtccaagccgcaggcgaaagccaag
cccgccgaatcgaagtcgtcgaccaagccggccgacgccaaatccgagaaatccggcaag
tcgggcaccaacggcgctgccaaacccgccgcccagcctgccgacgacagcgatcagaac
caggtgctgcgcggcgcggccgcggccgtcgccaagaacatgtcggcgtctctggacgtg
ccgaccgcgaccagcgtgcgcgccatcccggcgaagctgatgatcgacaaccgcgtcgtc
atcaacaaccacctcaagcgcacccgcggcggcaagatcagcttcacacacctgatcggc
tacgcgatcgtggcggcggtcaagaagttcccgaacatgaaccgccacttcgccgaggtc
gacggcaagcccaacgcggtcaccccggcgcacacgaacctaggtctggcgatcgacctg
cagggcaaggacggtaaccggcagctggtggtcgcggccatcaagaaggccgacaccatg
cggttcggccagttcatcgccgcgtacgaggacatcgtgcggcgcgcgcgcgacggcaag
ctcaccgccgaggacttctccggtgtgacgatctcgctgaccaacccgggcaccatcggc
accgtgcactcggtgccgcggctgatgcgcggtcagggcgcgatcatcggcgtcggcgcg
atggagtacccggcggagttccagggggccagcgaggaacgcatcgccgacctcggcatc
ggcaaactcatcacgctgacgtcgacctatgaccaccgcatcatccagggcgcggaatcc
ggtgacttcctgcggaccgtgcaccagctgctgctgtccgacgacttcttcgacgagatc
ttccgcgaactcggcatcccgtacgagccggtgcgctggcgcaccgacaaccccgattcg
atcgaggacaagaacgcccgcgtcatcgagctgatcgcggcctaccgcaaccgcggtcac
ctgatggccgacatcgacccgctccggttggacagcaaccgcttccgcagccaccccgac
ctcgacgtgctcacccacgggctgacgctgtgggatctggaccgcgagttcaaggtcaac
ggattcgccggtgctgagcgcaagaagctgcgtgacgtgctcgccgtgctgcgcgacgcc
tactgccgccacatcggcgtcgagtacacccacatcctcgaacccgaacagcagcagtgg
ctgcaggagcgcatcgagggcaaacacgagaagcccaccgtcgcgcagcagaagtacatc
ctgagccggctcaacgccgccgaggccttcgaaaccttcctgcagaccaaatacgttggg
cagaaacggttctcgctcgagggcgcggagaccgtcatcccggcgatggacgcggtgatc
gaccagtgcgccgagcatgcgctcgacgaggtcgtcatcggtatgccgcaccgcggccgg
ctcaacgtgctggccaacatcgtcggcaagccctacagccagatcttcagcgagttcgag
ggcaacctcaacccgtcgcaggcgcacggctccggcgacgtgaagtaccacctcggctcc
agcggcacctacctgcagatgttcggcgacaacgacatcacggtgtcgctgacggccaac
cccagccacctcgaggccgtcgacccggtgatggagggcctggtccgcgccaaacaggat
ctgctcgacaagggcgacaccgaggacggatacaccgtcgtcccgctgatgctgcacggc
gacgccgcattcgccggacagggtgtggtggccgagacgctgaacctggcgctgctgcgg
ggctaccgcaccggcggcaccatccacctgatcgtcaacaaccagatcggcttcaccacg
tcgccggcggccgcgaagtcgtcggagtactgcaccgacgtggcgaagatgatcggtgcg
ccgatcttccacgtcaacggcgacgatcccgaggccgcggtgtgggtgtccaggctggcc
gtcgacttccggcaaaagttcaagaaggacgtcgtcatcgacctgctgtgctaccgccgc
cgcgggcacaacgagggtgacgacccgtcgatgacccagccgtcgatgtacgacgtgatc
gacaccaaacgcggggtccgcaagagctacaccgaagcactgatcggccgcggcgacatc
tccatgaaagaggccgaggacgccctgcgcgactaccagggtcagctggagcaggtcttc
aacgaggtccgcgagctggagaagcacgagatcgagcccagcgaatcagtggaagccgac
cagcagatcccggccaaactcgccaccgcggtggacaaatcgctgctggcccgcatcggc
gacgcccacctggcggtgccggagggtttcaccgtgcacccccgcgtcaagccggtgctc
gagaagcgtcgcgagatggcctacgagggcaaggtcgactgggcgttcgccgaactgctg
gccctgggcaccatgatctccgagggcaaactggtccggctcagcggtcaggacacccgc
cgcggcacgttcacccagcggcactcggtggtgatcgaccgcaagaccggcaaggagttc
acgccgctgcagctgctggcgaccgactccgacggcaacccgaccggcggcaagttcctg
gtgtacgactcgccgctgtcggagttcgccgcggtgggcttcgagtacgggtactccgtc
ggcaacccggacgcaatggtgttgtgggaggcgcagttcggcgacttcatcaacggcgcc
cagtcgatcatcgacgagttcatcagttcgggtgaggccaagtggggtcagctctccgac
gtcgtgctgctgctgccgcacggccacgagggtcagggccccgaccacacctcgggccgc
atcgaacggttcctgcagctgtgggccgaagggtcgatgacgatcgcgctgccgtcgacg
ccggcgaactatttccacctgctgcgcaggcacagcctcgacgggatccagcggccgctg
atcgtcttcacgccgaagtcgatgctgcgcaacaaggccgcggtgtccgacatccgcgac
ttcaccgagcagaagttccgctcggtgctcgaggagccgacctacaccgacggcgacggc
gaccgcaacaaggtcacacggatcctgctcaccagcggcaagatctactacgagctggtg
gcgcgcaagaacaaggagagccgcgacgacgtggcgatcgtgcgcatcgaacagctcgca
ccgctgcccaaacggcggctggccgagacgctggacaagtacccgaacgtcgacgagaag
ttctgggtgcaggaggagccggccaaccagggtgcatggcccacgttcgggctgacgttg
cccgagatgctgccggaccacttcaccggcatcaagcggatctcgcgacgcgcgatgtcg
gcgccgtcgtcgggttcgtcgaaggtgcacgccgtcgaacagcaggagatcctcgacgag
gccttcgccccgtag

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