KEGG   Mycobacterium intracellulare subsp. intracellulare: MIP_02052
Entry
MIP_02052         CDS       T02325                                 
Name
(GenBank) 2-oxoglutarate decarboxylase
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
mid  Mycobacterium intracellulare subsp. intracellulare
Pathway
mid00020  Citrate cycle (TCA cycle)
mid00630  Glyoxylate and dicarboxylate metabolism
mid00785  Lipoic acid metabolism
mid01100  Metabolic pathways
mid01110  Biosynthesis of secondary metabolites
mid01120  Microbial metabolism in diverse environments
mid01200  Carbon metabolism
mid01210  2-Oxocarboxylic acid metabolism
Module
mid_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mid_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:mid00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    MIP_02052
   00630 Glyoxylate and dicarboxylate metabolism
    MIP_02052
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    MIP_02052
Enzymes [BR:mid01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     MIP_02052
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     MIP_02052
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     MIP_02052
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     MIP_02052
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh Transket_pyr OxoGdeHyase_C 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: AFS13411
UniProt: J9WDQ9
LinkDB
Position
complement(1461662..1465414)
AA seq 1250 aa
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGEAATATPTSGDGRP
AVAPAKPAAAAPAKPAAAAPESPKPAPPASTAPPASTAAGNGVPARPAPAKAAAPPPAEG
DELQTLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTH
LLGYALVQAIKKFPNMNRHYAEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKGC
ETMRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIG
VGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDAFW
DEIFRELGNPYLPVRWSTDNPDSIVDKTARVMELIAAYRNRGHLMADIDPLRLDGSRFRS
HPDLEILNHGLTLWDLDRVFKVNGFAGSEYKKLRDVLGLLRDAYCRHIGVEYTHILDPEQ
QEWLQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESIIPMMD
AAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYH
LGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDRRAEDQGDDKAFSV
VPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIANNQIGFTTAPEYSRSSEYCTD
VAKMIGAPIFHVNGDDPEACAWVAKLAVDFRQEFKKDVVIDMLCYRKRGHNEGDDPSMTN
PAMYDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGALP
SESVEADQMLPAGLSTAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKID
WAFAELLALGSLVAEGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGT
PTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEA
KWGQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHAL
DGVQRPLIVFTPKSMLRNKAVVSDVKDFTEIKFRSVLEEPTYEDGIGDRSKVSRVLLTSG
KLYYELMARKAKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPSVQEYFWVQEEPANQGAW
PRFGLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFG
NT seq 3753 nt   +upstreamnt  +downstreamnt
gtgagcaacataagttcaccattcggtcaaaacgaatggctggtcgaggagatgtaccgc
aagttccgcgatgacccctcgtcggtggatccgagctggcacgagttcctcgtcgactac
aaccccgagccgacgggcgaggcggcgacggccaccccgaccagcggcgatggccggccg
gccgtggcccccgccaagccggccgcagcggcccccgccaagccggccgcggcggccccc
gaaagccccaagcccgcgccccccgccagcacggcgccccccgccagcacggccgccggc
aacggggtcccggcgcgccccgcgccggcgaaggccgccgcccccccgccggccgaaggc
gacgagttgcagacgctgcgcggcgccgcggcggccgtcgtcaagaacatgtcggcgtcg
ctggaggtgccgacggcgaccagcgtgcgcgccgttcccgccaagctgctgatcgacaac
cggatcgtcatcaacaaccaactcaagcgcacgcgcggcggcaagatctcgttcacccac
ctgctcgggtacgcgctggtgcaggcgatcaagaagttcccgaacatgaatcggcactac
gccgaggtcgacggcaaacccaccgccgtcaccccggcgcacaccaacctgggcctggcg
atcgacctgcagggcaaggacggcaagcgttccttggtggtggccggcatcaagggctgc
gagaccatgcggttcgcgcagttcgtcaccgcctacgaagacatcgtgcggcgggcccgc
gacggcaagctgaccgccgaagactttgccggcgtgacgatttcgctgaccaacccgggc
accatcggcaccgtgcactcggtgccgcggctgatgaacggccagggcgccatcatcggc
gtcggcgccatggagtaccccgccgagttccagggcgccagcgaggaacgcatcgccgag
ctggggatcggcaagctgatcacgctgacctcgacctatgaccaccgcatcatccagggc
gcggaatccggcgacttcttgcgcacgatccacgagatgctgctctcggatgcgttctgg
gacgagatcttccgcgagctgggcaacccgtatctgccggtgcgctggagcaccgacaac
ccggactcgatcgtcgacaagaccgcccgggttatggaattgattgcggcctaccgcaat
cgcggccacctgatggccgacatcgacccactgcgcttggacggcagccggttccgcagc
caccccgacctcgagatcctcaaccacggcctgacgctgtgggatctcgatcgggtgttc
aaagtcaacggcttcgccggttccgagtacaagaagctgcgcgatgtgctgggcctgctg
cgcgatgcctactgccggcacatcggcgtggagtacacccacatcctcgatcccgagcag
caggagtggctgcaacagcgcgtcgagaccaagcacgtcaaaccgacggtggccgagcag
aagttcatcctgagcaaactgaacgcggccgaggccttcgagaccttcctgcagaccaaa
tacgttgggcagaaacggttttcactcgagggggcggaaagcatcattccgatgatggac
gcggcgatcgaccagtgcgccgagcacgggctcgacgaggtggtcatcgggatgccgcac
cgtggccggctcaacgtgctggccaacatcgtcggcaagccgtactcgcagatcttttcg
gagttcgagggcaacctcaaccccgcgcaggcgcacggctccggcgacgtcaaataccac
ctgggcgccaccggcgtttacctacagatgttcggcgacaacgacattcaggtgtcgctg
accgccaacccgtcgcacctggaagccgtcgacccggtgctggagggcctggtgcgcgcc
aagcaggacctgctggaccggcgcgccgaggaccagggggacgacaaggccttctcggtg
gtgccgatgatgctgcacggcgacgcggcgttcgccggtcagggcgtggtcgccgagacc
ctcaacctgacccacctgcccggttaccgcgtcggcggcaccatccacatcatcgccaac
aaccagattggcttcaccaccgcgccggagtactcacggtccagcgagtactgcaccgac
gtcgcgaagatgatcggggcgccgatcttccacgtcaacggcgacgacccggaggcgtgc
gcgtgggtggccaagctggcagtcgacttccggcaggagttcaagaaggacgtcgtcatc
gacatgctgtgctaccgcaagcgcgggcacaacgaaggcgatgacccgtcgatgaccaac
cccgccatgtacgacgtcgtcgacatcaagcgcggggtccggaagagctacaccgaggcc
ctgatcggccgcggcgacatctcgatgaaggaagccgaggacgccctgcgcgactaccag
ggccagctcgagcgggtgttcaacgaggtccgcgagctggagaagcacggcgcgctgccc
agcgaatcggtggaggccgaccagatgctgcccgcgggcctgtccaccgcggtggacaag
gcgttgctggcccgcatcggtgacgcgttcctggcgctacccgagggcttcacggcgcac
ccgcgggtgcagccggtcctggagaagcgccgggagatggcctacgagggcaagatcgac
tgggccttcgccgaactgctggcgctcggctcgctggtggccgagggcaagctggtgcgc
ctatcggggcaagacacccggcgcggcaccttctcgcagcgccactcggtgatcatcgac
cgcaacaccggcgaggagttcacgccgctgcagctgctggcgaccaaccccgacggcacc
cccaccggcggcaagttcctggtctacgactccccgctgtcggaatacgcggccgtcggc
ttcgagtacggctacaccgtgggcaacccggacgcgctcgtcctgtgggaagcccaattc
ggggacttcgtcaacggcgcgcagtcgatcatcgacgagttcatcagctccggcgaggcc
aagtggggccagctgtccaacgtggtgctgctgctgccgcacggccacgaaggccagggc
cccgaccacacctccggccgcatcgagcgcttcctgcagctgtgggcagagggttcgatg
acgatcgcgatgccctccacgccgtccaactatttccacttgttgcgccggcacgccctc
gacggggtgcagcgcccgctgatcgtgttcacgcccaagtcgatgctgcgcaacaaggcg
gtggtcagcgacgtcaaggacttcaccgagatcaagttccgctcggtgctcgaagagccg
acctacgaggacggcatcggcgatcgcagcaaggtcagcagggtcctgctgaccagcggc
aagctctactacgagttgatggcccgcaaggccaaggacaaccgggacgacgtggcgatc
gtgcggatcgagcagctcgccccgctgccgaagcgccggctgggcgaaacgctggaccgc
tacccgagcgtccaggagtacttctgggttcaggaagagccggccaaccagggcgcgtgg
ccgcgcttcggcctggaattgcccgagctgctgcccgacaagctgaccgggctcaagcgg
atttcccgccgggcgatgtcggccccgtcgtcgggctcgtcgaaggtgcacgccgtcgag
cagcaggagatcatcgacacggccttcggctga

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