KEGG   Micromonospora sp. B006: MicB006_4236
Entry
MicB006_4236      CDS       T05583                                 
Name
(GenBank) 2-oxoglutarate decarboxylase
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
micb  Micromonospora sp. B006
Pathway
micb00020  Citrate cycle (TCA cycle)
micb00630  Glyoxylate and dicarboxylate metabolism
micb00785  Lipoic acid metabolism
micb01100  Metabolic pathways
micb01110  Biosynthesis of secondary metabolites
micb01120  Microbial metabolism in diverse environments
micb01200  Carbon metabolism
micb01210  2-Oxocarboxylic acid metabolism
Module
micb_M00009  Citrate cycle (TCA cycle, Krebs cycle)
micb_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:micb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    MicB006_4236
   00630 Glyoxylate and dicarboxylate metabolism
    MicB006_4236
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    MicB006_4236
Enzymes [BR:micb01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     MicB006_4236
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     MicB006_4236
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     MicB006_4236
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     MicB006_4236
SSDB
Motif
Pfam: E1_dh OxoGdeHyase_C 2-oxoacid_dh Transket_pyr 2-oxogl_dehyd_N SHOCT-like_DUF2089-C
Other DBs
NCBI-ProteinID: AXO36505
LinkDB
Position
4699498..4703253
AA seq 1251 aa
MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDSAWHDFFADYRPAPGAATPRPDG
QAKPAAKPEPAEQQEAVATVKEQPAKAEPAKAEPKAAPKASAPAKPAAKPAAKTPEPAKK
SAPAKPAAKAPAASAAGTTTLRGVAAKIVQNMDASLSVPTATSVRAVPAKLLVDNRIVIN
NHLTRGRGGKVSFTHLIGYALVRAVVEHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLVK
PDGSRNLVVPSIKGCEQMDFRQFWQAYEDVVRRARRNELTMEDYSGTTISLTNPGGIGTV
HSIPRLMQGQSAIIGVGAMEYPAPYQGMSEATLAENAVSKVITLTSTYDHRIIQGAQSGE
FLKVMHELLLGERGFYDGIFTSLRIPYEPVRWMRDVAVDSEGQINKTARVHELIHAYRVR
GHLMADTDPLEFKIRKHPDLDVLQHGLTLWDLDRVFPVNGFAGQQRMKLRSILGVLRDSY
CRRVGIEYMHIQDPEERRWIQERVERKYEKPSQDEQKHVLNRLNAAEAFETFLQTKYVGQ
KRFSLEGGESLIPLLGEVLECSAEAGLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEG
HLDPRSTQGSGDVKYHLGQNGKFTTPDGEHAVKVSVVANPSHLEAVDPVLEGIVRAKQDR
IDLKLEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPE
YSRSSLYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQAFNKDVVIDMVCYRRRGH
NEGDDPSMSNPEMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQGQLERVFKAT
RDAATTPRQLSRPAREEEPEPQVDTATDASVVKAIGEAHVNLPEGFTPHKRIQQLLERRR
KMSVEGGIDWGFAEIIAFGTLLHDGVTVRLAGQDSRRGTFVQRHASVVDAKTGEDYLPLM
SLTADGERSRFFVHDSLLSEYAAMGFEYGYSVENINALVAWEAQFGDFVNGAQSVIDEFI
SSGEVKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVAIPTTPANYFHLL
RRQALSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFSPVLADTAAPAPEQVKRVLLCS
GKVYYDLFQARQERGVTNTAIIRMEQLYPLPVEEVRAALAQYPNAEDFAWVQEEPANQGA
WSFVALNLLEHLPEVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq 3756 nt   +upstreamnt  +downstreamnt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgctacctcgccgacccctcgagcgtcgattcggcctgg
cacgacttcttcgccgactaccggccggccccgggcgccgccacaccgcgcccggacggg
caggccaagccggccgcgaagcctgagccggccgagcagcaggaagcagtggccacggtc
aaggagcagcccgccaaggcggagcccgccaaggccgagccgaaggccgccccgaaggcg
tccgccccggccaagcccgccgccaagccggcggcgaagacccccgagccggcgaagaag
tccgcaccggccaagcccgccgcgaaggcaccggccgcgagcgccgccggcaccacgacg
ctgcgcggcgtggccgccaagatcgttcagaacatggacgcgtcgctgtcggtcccgacc
gccaccagcgtgcgcgccgtcccggccaagctgctggtcgacaaccgcatcgtgatcaac
aaccacctcacccggggtcgcggcggcaaggtcagcttcacccacctgatcgggtacgcg
ctggtgcgcgccgtcgtcgagcacccggagatgaacaactccttcgccgaggtcgacggc
aagccggcgatggtccgcccggagcacgtcaacctgggcatcgcgatcgacctggtcaag
ccggacggctcccgcaacctggtggtgccgtccatcaagggctgcgagcagatggacttc
cggcagttctggcaggcgtacgaggacgtggtccggcgcgcccgccgcaacgagctgacc
atggaggactactccggcaccacgatctcgctgaccaacccgggcggcatcggcaccgtg
cactcgatcccgcgcctgatgcaggggcagagcgccatcatcggcgtcggggcgatggag
tacccggccccctaccagggcatgagcgaggccaccctggccgagaacgcggtcagcaag
gtcatcacgctgaccagcacgtacgaccaccggatcatccagggcgcgcagtccggcgag
ttcctgaaggtcatgcacgagctgctgctcggcgagcgcggcttctacgacggcatcttc
acctcgctgcgcatcccgtacgagccggtgcgctggatgcgcgacgtggccgtcgacagc
gagggccagatcaacaagaccgcgcgggtgcacgagctgatccacgcgtaccgggtgcgc
ggccacctgatggccgacaccgacccgctggagttcaagatccgtaagcacccggacctt
gacgtgctccagcacgggctcacgctctgggacctcgaccgcgtcttcccggtcaacggc
ttcgccggccagcagcggatgaagctgcgctcgatcctcggcgtgctgcgtgactcgtac
tgccgccgggtcggcatcgagtacatgcacatccaggacccggaggagcggcgctggatc
caggagcgcgtcgagcgcaagtacgagaagccgagccaggacgagcagaagcacgtgctg
aaccggctcaacgccgccgaggcgttcgagacgttcctgcagaccaagtacgtcggccag
aagcgcttctcgctggagggcggcgagtcgctgatcccgctgctcggcgaggtgctggag
tgctccgccgaggccgggctggacgaggtcgtcatcggcatggcccaccgcggccggctc
aacgtgctggcgaacatcgtcggcaagccgtacgagaagatcttctccgagttcgagggg
cacctcgacccgcgctccacgcagggctcgggcgacgtgaagtaccacctcgggcagaac
ggcaagttcaccaccccggacggcgagcacgcggtcaaggtgtcggtggtggcgaacccg
tcgcacctggaggccgtcgacccggtgctggagggaatagtccgggccaagcaggaccgg
atcgacctcaagctggagggctacaccgtgctgccgctggcggtgcacggtgacgccgcc
ttcgccggccagggtgtggtcgccgagacgctcaacctgtctcagctgcgcggctaccgc
accggcggcaccgtgcacgtggtcgtgaacaaccaggtcggcttcaccaccgccccggag
tacagccggtccagcctctacagcaccgacgtggcccggatgatccaggcgccgatcttc
cacgtgaacggcgacgacccggaggcagtggtccgggtggcccggctcgcgttcgagtac
cggcaggcgttcaacaaggacgtcgtgatcgacatggtctgctaccgccggcgcgggcac
aacgagggcgacgacccgtcgatgtccaacccggagatgtacaagatcatcgactcgaag
cgctcggtccggaagctctacaccgaagagctgatcgggcgcggcgacatcaccgtggag
gacgcggaggagctgctgcgcgactaccaggggcagctggagcgggtcttcaaggccacc
cgggacgccgcgaccacgccgcgccagctcagccgcccggcgcgggaggaggagccggag
ccgcaggtcgacaccgccaccgacgcctcggtggtcaaggcgatcggcgaggcgcacgtc
aacctgccggagggcttcaccccgcacaagcggatccagcagctgctggagcggcgccgc
aagatgtccgtcgagggcggcatcgactggggcttcgccgagatcatcgcgttcggcacg
ctgctgcacgacggcgtcacggtccggctcgccgggcaggactcccgccgcggcacgttc
gtccagcggcacgcctcggtggtcgacgccaagaccggcgaggactacctgccgctgatg
tcgctcaccgccgacggcgagcggtcgcgtttcttcgtccacgactcgctgctctccgag
tacgcggccatgggcttcgagtacggctactcggtggagaacatcaacgcgctggtggcc
tgggaggcccagttcggtgacttcgtcaacggcgcccagtcggtgatcgacgagttcatc
tcctccggcgaggtgaagtggggtcagcgctccgcggtgacgctgctgctgccgcacggc
cacgagggccagggcccggaccacacctccggccgcccggagcggttcctgcagctctgc
gccgaggacaacatgcgggtggccatcccgaccaccccggcgaactacttccacctgctg
cgccgccaggccctgtcgcccaagcgcaagccgctggtggtgttcacgccgaagtcgctg
ctgcggcacaagctctgcgtgtcgccggtggaggacttcaccaccggcacgttctccccg
gtgctggccgacaccgcggctccggcgccggagcaggtcaagcgggtgctgctctgctcg
ggcaaggtctactacgacctgttccaggcccggcaggagcggggcgtcacgaacaccgcg
atcatccggatggagcagctctacccgctgcccgtcgaggaggtccgggccgctctggcg
cagtacccgaacgccgaggacttcgcctgggtccaggaggagccggccaaccagggcgcc
tggtcgttcgtcgcgctgaacctgctggagcacctgcccgaggtccggctgcgccgtatc
tcccggcccgccgccgccgctccggcggtcggctcggcgaagatgcacgaggtcgagcag
aacgcgctgatcgaggcggctctcccccgcccgtga

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