Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2: BCG_1308c
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Entry
BCG_1308c CDS
T00463
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mbb
Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2
Pathway
mbb00020
Citrate cycle (TCA cycle)
mbb00630
Glyoxylate and dicarboxylate metabolism
mbb00785
Lipoic acid metabolism
mbb01100
Metabolic pathways
mbb01110
Biosynthesis of secondary metabolites
mbb01120
Microbial metabolism in diverse environments
mbb01200
Carbon metabolism
mbb01210
2-Oxocarboxylic acid metabolism
Module
mbb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mbb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
BCG_1308c (kgd)
00630 Glyoxylate and dicarboxylate metabolism
BCG_1308c (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BCG_1308c (kgd)
Enzymes [BR:
mbb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
BCG_1308c (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
BCG_1308c (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
BCG_1308c (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
BCG_1308c (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CAL71295
UniProt:
A1KI36
LinkDB
All DBs
Position
complement(1419079..1422723)
Genome browser
AA seq
1214 aa
AA seq
DB search
MYRKFRDDPSSVDPSWHEFLVDYSPEPTSQPAAEPTRVTSPLVAERAAAAAPQAPPKPAD
TAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAKL
LIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHTN
LGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISL
TNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHR
IIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLIA
AYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRDV
LGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETF
LQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYS
QIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEG
LVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIH
IIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKK
DVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISMKEAEDAL
RDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNG
FTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHS
VLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLW
EAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWA
EGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSV
LEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLRE
TLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKV
HAVEQQEILDEAFG
NT seq
3645 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcaagttccgcgacgacccctcctcggtcgatcccagctggcacgagttcctg
gttgactacagccccgaacccacctcccaaccagctgccgaaccaacccgggttacctcg
ccactcgttgccgagcgggccgctgcggccgccccgcaggcaccccccaagccggccgac
accgcggccgcgggcaacggcgtggtcgccgcactggccgccaaaactgccgttcccccg
ccagccgaaggtgacgaggtagcggtgctgcgcggcgccgccgcggccgtcgtcaagaac
atgtccgcgtcgttggaggtgccgacggcgaccagcgtccgggcggtcccggccaagcta
ctgatcgacaaccggatcgtcatcaacaaccagttgaagcggacccgcggcggcaagatc
tcgttcacgcatttgctgggctacgccctggtgcaggcggtgaagaaattcccgaacatg
aaccggcactacaccgaagtcgacggcaagcccaccgcggtcacgccggcgcacaccaat
ctcggcctggcgatcgacctgcaaggcaaggacgggaagcgttccctggtggtggccggc
atcaagcggtgcgagaccatgcgattcgcgcagttcgtcacggcctacgaagacatcgta
cgccgggcccgcgacggcaagctgaccactgaagactttgccggcgtgacgatttcgctg
accaatcccggaaccatcggcaccgtgcattcggtgccgcggctgatgcccggccagggc
gccatcatcggcgtgggcgccatggaataccccgccgagtttcaaggcgccagcgaggaa
cgcatcgccgagctgggcatcggcaaattgatcactttgacctccacctacgaccaccgc
atcatccagggcgcggaatcgggcgacttcctgcgcaccatccacgagttgctgctctcg
gatggcttctgggacgaggtcttccgcgaactgagcatcccatatctgccggtgcgctgg
agcaccgacaaccccgactcgatcgtcgacaagaacgctcgcgtcatgaacttgatcgcg
gcctaccgcaaccgcggccatctgatggccgataccgacccgctgcggttggacaaagct
cggttccgcagtcaccccgacctcgaagtgctgacccacggcctgacgctgtgggatctc
gatcgggtgttcaaggtcgacggctttgccggtgcgcagtacaagaaactgcgcgacgtg
ctgggcttgctgcgcgatgcctactgccgccacatcggcgtggagtacgcccatatcctc
gaccccgaacaaaaggagtggctcgaacaacgggtcgagaccaagcacgtcaaacccact
gtggcccaacagaaatacatcctcagcaagctcaacgccgccgaggcctttgaaacgttc
ctacagaccaagtacgtcggccagaagcggttctcgctggaaggcgccgaaagcgtgatc
ccgatgatggacgcggcgatcgaccagtgcgctgagcacggcctcgacgaggtggtcatc
gggatgccgcaccggggccggctcaacgtgctggccaacatcgtcggcaagccgtactcg
cagatcttcaccgagttcgagggcaacctgaatccgtcgcaggcgcacggctccggtgac
gtcaagtaccacctgggcgccaccgggctgtacctgcagatgttcggcgacaacgacatt
caggtgtcgctgaccgccaacccgtcgcatctggaggccgtcgacccggtgctggaggga
ttggtgcgggccaagcaggatctgctcgaccacggaagcatcgacagcgacggccaacgg
gcgttctcggtggtgccgctgatgttgcatggcgatgccgcgttcgccggtcagggtgtg
gtcgccgagacgctgaacctggcgaatctgccgggctaccgcgtcggcggcaccatccac
atcatcgtcaacaaccagatcggcttcaccaccgcgcccgagtattccaggtccagcgag
tactgcaccgacgtcgcaaagatgatcggggcaccgatctttcacgtcaacggcgacgac
ccggaggcgtgtgtctgggtggcgcggttggcggtggacttccgacaacggttcaagaag
gacgtcgtcatcgacatgctgtgctaccgccgccgcgggcacaacgagggtgacgacccg
tcgatgaccaacccctacatgtacgacgtcgtcgacaccaagcgcggggcccgcaaaagc
tacaccgaagccctgatcggacgtggcgacatctcgatgaaggaggccgaggacgcgctg
cgcgactaccagggccagctggaacgggtgttcaacgaagtgcgcgagctggagaagcac
ggtgtgcagccgagcgagtcggtcgagtccgaccagatgattcccgcggggctggccact
gcggtggacaagtcgctgctggcccggatcggcgatgcgttcctcgccttgccgaacggc
ttcaccgcgcacccgcgagtccaaccggtgctggagaagcgccgggagatggcctatgaa
ggcaagatcgactgggcctttggcgagctgctggcgctgggctcgctggtggccgaaggc
aagctggtgcgcttgtcggggcaggacagccgccgcggcaccttctcccagcggcattcg
gttctcatcgaccgccacactggcgaggagttcacaccactgcagctgctggcgaccaac
tccgacggcagcccgaccggcggaaagttcctggtctacgactcgccactgtcggagtac
gccgccgtcggcttcgagtacggctacactgtgggcaatccggacgccgtggtgctctgg
gaggcgcagttcggcgacttcgtcaacggcgcacagtcgatcatcgacgagttcatcagc
tccggtgaggccaagtggggccaattgtccaacgtcgtgctgctgttaccgcacgggcac
gaggggcagggacccgaccacacttctgcccggatcgaacgcttcttgcagttgtgggcg
gaaggttcgatgaccatcgcgatgccgtcgactccgtcgaactacttccacctgctacgc
cggcatgccctggacggcatccaacgcccgctgatcgtgttcacgcccaagtcgatgttg
cgtcacaaggccgccgtcagcgaaatcaaggacttcaccgagatcaagttccgctcagtg
ctggaggaacccacctatgaggacggcatcggagaccgcaacaaggtcagccggatcctg
ctgaccagtggcaagctgtattacgagctggccgcccgcaaggccaaggacaaccgcaat
gacctcgcgatcgtgcggcttgaacagctcgccccgctgcccaggcgtcgactgcgtgaa
acgctggaccgctacgagaacgtcaaggagttcttctgggtccaagaggaaccggccaac
cagggtgcgtggccgcgattcgggctcgaactacccgagctgctgcctgacaagttggcc
gggatcaagcgaatctcgcgccgggcgatgtcagccccgtcgtcaggctcgtcgaaggtg
cacgccgtcgaacagcaggagatcctcgacgaggcgttcggctga
DBGET
integrated database retrieval system
