KEGG   Leptonychotes weddellii (Weddell seal): 102731014
Entry
102731014         CDS       T08708                                 
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
  KO
K13368  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00140  Steroid hormone biosynthesis
lww01100  Metabolic pathways
lww04913  Ovarian steroidogenesis
Module
lww_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:lww00001]
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102731014 (HSD17B2)
Enzymes [BR:lww01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     102731014 (HSD17B2)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     102731014 (HSD17B2)
SSDB
Motif
Pfam: adh_short adh_short_C2 Epimerase KR DUF2854
Other DBs
NCBI-GeneID: 102731014
NCBI-ProteinID: XP_030875376
UniProt: A0A7F8Q4E6
LinkDB
Position
Unknown
AA seq 409 aa
MSVLNPCSSEVCQSHFLPLPSCLSVHITQAAAPSLCPLVSLVLSTQRCSTSLRMSTFSET
AWLCLAVTVVLAGIALCSLKKSPGQAGRKVVCLAGLWGGAYLLLSLPLSWSLILCLLSCF
LLYTYLSGQELLPVDQKAVLITGGDSGFGHALSKYLDELGFTVFVGVLDETGSGAEELRR
TCSERLSVLQMDITDPQQIKDAHRKVVEKLQNRVHLAADHTLRTPVPATCHLFNRPPLTW
ASGRHKDGMRGVPMEKLAAYSSSKAALTMFSAVMRQELSKWGIKVSVIQPGGFRTNIAGT
SEVWSKQEKDLLDHLTSDVQEDYGQDYILEQRNYLKLINMKASKDMSPVLLDIRHAVSAK
SPFAFYAPGAMAYSLICFVSFSPTGIFDYFSKKLHNFGGGLPRALIKQA
NT seq 1230 nt   +upstreamnt  +downstreamnt
atgagtgtgcttaatccctgctcatccgaagtgtgccagagccactttctccccctccct
tcttgcctctctgtacatataacccaggctgctgcacccagcctttgcccgcttgtctcg
ctggtcctgagcactcaaaggtgcagcacgtctctgagaatgagcaccttctctgagaca
gcgtggctctgcctggctgtcaccgtagtgctagcaggaatagccctttgcagtctcaag
aagagcccagggcaggccggcagaaaggtggtctgcctggcgggtctctggggaggggct
tacctgctgctcagcctgcccctctcctggagcttgatcctctgcctcctgtcctgcttc
ctcctgtatacttacctctctggtcaagagctgttacctgtggatcaaaaggcggtgcta
atcacaggtggcgattccggatttggccatgctctgtctaaatatctggatgagcttggc
ttcacggtatttgtgggagttctggatgaaacaggatcaggagcagaggaattgcgaaga
acctgctccgagcgcctctctgtgctccagatggacatcaccgacccacagcagataaaa
gacgcccacagaaaagtggtggaaaagttgcagaacagagtccatctggctgctgaccac
accttgaggacacctgtaccagccacctgtcacttgttcaaccgcccccccctgacatgg
gcctctggcagacacaaagatggtatgagaggggtcccaatggaaaagctggcagcctat
agctcatccaaggcggctctgaccatgttctcagcagtcatgagacaggagctttccaaa
tggggaattaaagtctctgtcatccagcctggaggcttcaggacgaatattgcaggcacc
agtgaagtgtggagcaagcaggagaaggacctcttggaccaccttacctctgacgttcag
gaagactatggccaggactatatcctcgagcagcggaattatcttaagttgatcaacatg
aaggccagcaaagatatgtcccctgtgctcctggacatccgacatgctgtgtctgctaag
agcccctttgccttttatgcgccgggcgcaatggcttattcgttgatctgctttgtttcc
tttagtcctactggcatatttgattattttagcaaaaaattgcataactttggaggaggc
ttgcccagggcactaattaaacaggcctaa

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