KEGG   Lynx rufus (bobcat): 124524747
Entry
124524747         CDS       T08475                                 
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf00140  Steroid hormone biosynthesis
lruf00980  Metabolism of xenobiotics by cytochrome P450
lruf01100  Metabolic pathways
lruf05204  Chemical carcinogenesis - DNA adducts
Module
lruf_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    124524747
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    124524747
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    124524747
Enzymes [BR:lruf01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     124524747
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776
Other DBs
NCBI-GeneID: 124524747
NCBI-ProteinID: XP_046953090
LinkDB
Position
Unknown
AA seq 287 aa
MKVLLFTGLGALFFSYYWDDNFDPASLQGARVLLTGASAGVGEELAYHYARLGSHLVLTA
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEVPERVVQFALDKLGGLDYLVLNHLGATP
AGSRSRSVQATRWLMQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGQVPTSFSRPYSA
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASPAEGVRGVTRAKAAPGPKAALAV
IRGGATRAPGVFYPWRFHLLCLLRGWLPHPRAWFVRQELNVTAAAAA
NT seq 864 nt   +upstreamnt  +downstreamnt
atgaaggtactgctcttcaccgggctgggagccctgttcttctcgtattactgggatgac
aactttgaccctgccagcctccagggagcccgcgtgctgctgacaggggccagtgcgggc
gtcggggaggaactggcatatcactacgcccgcctgggctcccacctggtgctcactgcc
cacacggaggccctcctgcagaaggtggtagggaactgccggaagctgggcgctcccaag
gtcttctacatcgctgcggacatggcctcccctgaggtgcccgagcgcgtggtgcagttc
gcgctggacaagctgggaggactggactacctcgtgctgaaccacctcggcgccaccccg
gcaggctcgcggtccaggagcgtccaggccactcgctggctcatgcaggtgaactttttg
agttacgtgcagctgacttcgttggcgctgcccagcctgacggacagcaaaggctctctg
gtggtcgtgtcctcgctgctcggccaggtgcccacatccttctcccgcccgtactcggca
gccaagttcgctctggacggcttcttcggctctctgcggcgggagctagacgtgcaggac
gtgaacgtggccatcaccatgtgtgtcctgggcctccgggatcgcgcctcccccgccgag
ggagtcaggggcgtcacgagggccaaggcggccccagggcccaaggcggccctggccgtg
atccgcggcggcgccacacgcgcccccggcgtcttctacccatggcgcttccacctgctc
tgtctgctccggggatggctgccgcacccgagggcctggttcgtccgccaggagctcaac
gtcaccgctgccgctgctgcctga

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