Entry |
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Symbol |
MAPKAPK2, MAPKAP-K2, MK-2, MK2
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Name |
(RefSeq) MAPK activated protein kinase 2
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KO |
K04443 | mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] |
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Organism |
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Pathway |
hsa04625 | C-type lectin receptor signaling pathway |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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Network |
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Element |
N00186 | IL1-IL1R-p38 signaling pathway |
N00187 | KSHV Kaposin B to p38 signaling pathway |
N01776 | CaMK2-p38-MK2-ALOX5 pathway |
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Drug target |
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Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
9261 (MAPKAPK2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
9261 (MAPKAPK2)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
9261 (MAPKAPK2)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
9261 (MAPKAPK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
9261 (MAPKAPK2)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
9261 (MAPKAPK2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CAMK group
MAPKAPK family [OT]
9261 (MAPKAPK2)
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SSDB |
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Motif |
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Other DBs |
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Structure |
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LinkDB |
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Position |
1:206684905..206734281
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AA seq |
400 aa
MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH |
NT seq |
1203 nt +upstreamnt +downstreamnt
atgctgtccaactcccagggccagagcccgccggtgccgttccccgccccggccccgccg
ccgcagccccccacccctgccctgccgcaccccccggcgcagccgccgccgccgcccccg
cagcagttcccgcagttccacgtcaagtccggcctgcagatcaagaagaacgccatcatc
gatgactacaaggtcaccagccaggtcctggggctgggcatcaacggcaaagttttgcag
atcttcaacaagaggacccaggagaaattcgccctcaaaatgcttcaggactgccccaag
gcccgcagggaggtggagctgcactggcgggcctcccagtgcccgcacatcgtacggatc
gtggatgtgtacgagaatctgtacgcagggaggaagtgcctgctgattgtcatggaatgt
ttggacggtggagaactctttagccgaatccaggatcgaggagaccaggcattcacagaa
agagaagcatccgaaatcatgaagagcatcggtgaggccatccagtatctgcattcaatc
aacattgcccatcgggatgtcaagcctgagaatctcttatacacctccaaaaggcccaac
gccatcctgaaactcactgactttggctttgccaaggaaaccaccagccacaactctttg
accactccttgttatacaccgtactatgtggctccagaagtgctgggtccagagaagtat
gacaagtcctgtgacatgtggtccctgggtgtcatcatgtacatcctgctgtgtgggtat
ccccccttctactccaaccacggccttgccatctctccgggcatgaagactcgcatccga
atgggccagtatgaatttcccaacccagaatggtcagaagtatcagaggaagtgaagatg
ctcattcggaatctgctgaaaacagagcccacccagagaatgaccatcaccgagtttatg
aaccacccttggatcatgcaatcaacaaaggtccctcaaaccccactgcacaccagccgg
gtcctgaaggaggacaaggagcggtgggaggatgtcaaggaggagatgaccagtgccttg
gccacaatgcgcgttgactacgagcagatcaagataaaaaagattgaagatgcatccaac
cctctgctgctgaagaggcggaagaaagctcgggccctggaggctgcggctctggcccac
tga |