Entry |
|
Symbol |
FLT3LG, FL, FLG3L, FLT3L, IMD125
|
Name |
(RefSeq) fms related receptor tyrosine kinase 3 ligand
|
KO |
K05454 | fms-related tyrosine kinase 3 ligand |
|
Organism |
|
Pathway |
|
Network |
|
Element |
N00217 | FLT3LG-FLT3-RAS-ERK signaling pathway |
N00218 | FLT3LG-FLT3-RAS-PI3K signaling pathway |
N00219 | FLT3LG-FLT3-STAT5 signaling pathway |
N01592 | GF-RTK-RAS-ERK signaling pathway |
N01656 | GF-RTK-PI3K signaling pathway |
N01658 | GF-RTK-RAS-PI3K signaling pathway |
|
Disease |
H01725 | Primary immunodeficiency disease |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
2323 (FLT3LG)
04151 PI3K-Akt signaling pathway
2323 (FLT3LG)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
2323 (FLT3LG)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
2323 (FLT3LG)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:hsa04052]
2323 (FLT3LG)
Cytokines and neuropeptides [BR:hsa04052]
Cytokines
Growth factors (RTK binding)
2323 (FLT3LG)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
LinkDB |
|
Position |
19:49474215..49486231
|
AA seq |
235 aa
MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTV
ASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCL
RFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPT
APQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH |
NT seq |
708 nt +upstreamnt +downstreamnt
atgacagtgctggcgccagcctggagcccaacaacctatctcctcctgctgctgctgctg
agctcgggactcagtgggacccaggactgctccttccaacacagccccatctcctccgac
ttcgctgtcaaaatccgtgagctgtctgactacctgcttcaagattacccagtcaccgtg
gcctccaacctgcaggacgaggagctctgcgggggcctctggcggctggtcctggcacag
cgctggatggagcggctcaagactgtcgctgggtccaagatgcaaggcttgctggagcgc
gtgaacacggagatacactttgtcaccaaatgtgcctttcagcccccccccagctgtctt
cgcttcgtccagaccaacatctcccgcctcctgcaggagacctccgagcagctggtggcg
ctgaagccctggatcactcgccagaacttctcccggtgcctggagctgcagtgtcagccc
gactcctcaaccctgccacccccatggagtccccggcccctggaggccacagccccgaca
gccccgcagccccctctgctcctcctactgctgctgcccgtgggcctcctgctgctggcc
gctgcctggtgcctgcactggcagaggacgcggcggaggacaccccgccctggggagcag
gtgccccccgtccccagtccccaggacctgctgcttgtggagcactga |