Hyaena hyaena (striped hyena): 120248107
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Entry
120248107 CDS
T07257
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00061
Fatty acid biosynthesis
hhv00620
Pyruvate metabolism
hhv00640
Propanoate metabolism
hhv01100
Metabolic pathways
hhv01212
Fatty acid metabolism
hhv04152
AMPK signaling pathway
hhv04910
Insulin signaling pathway
hhv04922
Glucagon signaling pathway
hhv04936
Alcoholic liver disease
Module
hhv_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
120248107 (ACACA)
00640 Propanoate metabolism
120248107 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
120248107 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
120248107 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
120248107 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
120248107 (ACACA)
04922 Glucagon signaling pathway
120248107 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
120248107 (ACACA)
Enzymes [BR:
hhv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
120248107 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
120248107 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
120248107 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
120248107
NCBI-ProteinID:
XP_039112253
LinkDB
All DBs
Position
Unknown
AA seq
2346 aa
AA seq
DB search
MGEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPVSVGSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYQKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQTEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAVESGCIHYVKRPGTALDPGCVIAKMQLDNPSKVQQAELHTGSLPRNQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTPLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
FLPSPPLPSDILTYTELVLDDQGQLVRMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDLLFLRASEFARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKNVHSLVPILNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVLVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYISLAERLGTPELSPVE
RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGARSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq
7041 nt
NT seq
+upstream
nt +downstream
nt
atgggtgaaccatcccccttggccaaacctctggagctgaaccagcactctcggttcata
attggttctgtgtctgaagataactcagaggatgaaatcagcaacctggtgaagctggac
ctactggaggagaaggagggctctctgtcaccagtttccgttggctcagatacactctct
gatttggggatttccagcctacaggacggcttggccttgcacatgaggtccagcatgtct
ggcttgcatctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcttctccagcagaatttgttactcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcattgctgcagtgaaatgcatgcgatccatccgtcggtgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactatgtgcccgtgccagga
ggaccaaacaacaacaattacgcgaacgtggaattaattctcgatattgctaaaaggatc
ccagtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggctatgtgggctttg
ggggataagattgcatcttccatagtggctcaaactgctggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggactggcaggaaaatgacttttcaaaacgtatcttaaat
gttccccaggaattatatcaaaaaggttatgtgaaggatgtggatgatggactgaaggca
gcggaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaagga
atcagaaaagtcaataatgcagatgacttccctaacctcttcagacaggttcaaactgaa
gtccctggatctcctatatttgtgatgagactagccaaacaatcccgtcatctggaggta
cagatcttagcagatcagtatggcaatgctatctctctgtttggtcgtgactgctccgta
cagcgcaggcatcagaagattattgaagaagcaccagctgctattgctactccagcagta
tttgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgcg
gggactgttgaatacctctacagccaggatggaagcttctactttctggaactaaaccct
cggctacaggtggagcacccttgtacagagatggtagctgatgtcaacctccctgcagca
caactccagattgccatggggatccctctgtacagaatcaaggatattcgtatgatgtat
ggagtatctccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttat
ttcagtgttgctgctgcagggggccttcatgaatttgctgattctcagtttggtcattgc
ttctcctggggagaaaacagagaggaagcaatttcaaacatggtggtagctttgaaggag
ctatctattcggggtgactttcgaactacagttgaatatctcatcaaattgttggagacc
gagagctttcagttgaatagaattgacactggctggctagacagactgatagcagaaaaa
gtacaggcagagcgacctgacaccatgttgggagttgtgtgtggggctctccacgtggca
gatgtgagcctgcggaatagcatctctaacttccttcactccttagaaaggggtcaagtt
cttcctgctcatacacttctgaatacagtagatgttgagcttatctatgagggagtcaaa
tatgtacttaaggtgactcgacagtcccccaactcctacgtggtgatcatgaacggctca
tgcgtagaagtagatgtgcatcggctgagtgacggagggctgctcctgtcctatgatggc
agcagttataccacatacatgaaggaggaagtggatagatatcgcatcacaattggcaat
aagacctgtgtttttgagaaggaaaatgacccatcagtgatgcgttcaccttctgctggg
aaattaatccagtatattgtggaggatggaggccatgtgtttgctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagctgtagagtctggctgtatccat
tatgtcaaacggcctggaacagctcttgaccctggctgtgtaatagccaaaatgcagtta
gacaaccccagcaaggtccaacaggctgagcttcacacaggtagtctaccacggaaccag
agcacagcactgagaggcgagaagctccatcgagtgttccattatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttttttagcagcagggtaaaagac
tgggtggagcggttaatgaagacgctcagagatccttccttgcctctcctagaattgcaa
gatatcatgaccagtgtctctggtcgtattccccccaatgtggagaagtctatcaagaag
gaaatggctcaatatgccagtaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgggaagtt
ttcttcatgaacactcagagcattgtccagctggtacagagataccgaagtggcatccga
ggccacatgaaggctgtggtgatggatctgctgcggcagtacctgagagtagagacacag
ttccagaatggtcactatgacaaatgtgtgttcgcccttcgagaagaaaacaagagtgac
atgaacactgtgctgaactatatcttctctcacgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggtcgggaccctactctcactgatgagctgctg
aatatcctcacagagctaactcaactcagtaagaccaccaatgccaaagtggcactgcga
gcacgccaggttcttattgcctcccatttgccatcgtatgagcttcgccataaccaagta
gagtctatcttcctttcagctattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctatttttgatgttctaccaaatttcttctatcac
agcaaccaggtagtgaggatggcagctctggaggtttatgttcgaagggcttacattgcc
tatgaacttaacagcgtacagcatcgccagcttaaggacaatacctgcgtggtggaattc
cagttcatgctgcccacatctcatccaaacagagggaacatccccacgcttaacagaatg
tccttctcctccaacctcaaccactatggcatgactcacgtagctagtgtcagcgatgtg
ctgttggacaactcattcactccaccatgtcagcggatgggtggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgattcccca
ccccaaagccccacgttccctgaagcaggtcacacacctctgtatgatgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaagactgactgtgatattgag
gatgacagactggcagctatgttcagagagtttacccaacaaaataaagctaccctggtt
gagcatgggatacggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtc
aactatgaggtggatcagagatttcatagagaatttcctaaatttttcacgttccgagca
agggataagtttgaggaggatcgtatctatcgtcacctggagcctgccctagctttccag
ttagagctgaaccggatgagaaattttgaccttactgccattccatgtgctaatcataaa
atgcacctgtatcttggggcagccaaggtggaagtgggcactgaagtgacagactacagg
ttctttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaa
tatctacaaaatgaaggggagaggctgctcctggaggccatggatgaattggaagttgct
tttaataatacaaatgttcgcactgactgcaaccatatcttcctcaactttgtgcccaca
gtcattatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctacgga
agtcggctgtggaaattacgtgtcctccaggcagaactgaaaatcaacattcgccttaca
ccaactggaaaagcaattcccatccgcctcttcctgacaaacgagtccggctattacttg
gacatcagcttgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggca
tatggagacaaacagggaccattgcatggaatgttaatcaacactccatatgtcaccaaa
gacctccttcaatcaaagagattccaggcacaatccttggggacaacatacatatatgat
atcccagagatgtttcgacagtctctgatcaaactctgggagtctatgtccactcaagca
ttccttccatcaccccccctgccttctgacatactaacatatactgagctcgtgttggat
gatcaaggtcagctggtccgcatgaacaggcttccgggaggaaatgagattggcatggta
gcttggaaaatgacccttaaaagtcctgaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacataccgaattgggtcctttgggccccaagaagatttgctgtttctc
agagcttctgagtttgccagggcagagggcatcccacgcatctttgtagcagccaacagc
ggagcacgaattggactggcagaggaaattcgtcatatgtttcatgtggcctgggtagac
cctgaggatccttacaagggatacaaatacttatatctgacccctcaggattataagaga
gtcagtgctctcaactctgtccattgtgaacatgtagaggatgaaggagaatccaggtac
aagataaccgatattattgggaaggaagagggacttggagcagagaaccttcgaggctct
ggaatgattgctggagaatcctcattggcctatgatgagatcatcaccatcagcttggtt
acatgccgggctattggaattggggcttaccttgtccggctgggacagagaacaatccag
gttgaaaattctcacttaattctgactggagctggagccctcaacaaagtccttgggcgg
gaagtatacacctccaataaccagctcgggggcatccagatcatgcacaacaatggggtg
acccacagcaccgtttgtgatgactttgaaggggttttcactgtcctgcactggctgtct
tacatgcctaagaatgtgcacagtttagtacctatcctgaactccaaggatcctatagat
agaatcatcgaatttgttcctacgaaggccccatatgatcctcgatggatgctagcaggc
cgtcctcacccaacccaaaaaggtcagtggttgagtggattctttgactatggatctttc
tctgagatcatgcaaccctgggcgcagactgtggtggttggcagagccaggctaggagga
atacctgtaggagtagttgccgtagaaacccgaacagtggagctaagtatcccagccgac
cctgcaaacctggattctgaagccaagataatccagcaggctggccaggtttggtttcca
gattctgcgtttaagacctatcaggctatcaaggacttcaaccgtgaagggctacctctg
atggtctttgccaactggagaggcttctccggtgggatgaaagatatgtatgaccaagtg
ctgaagtttggtgcttacatcgtggatggcttgcgggagtgctcccagcctgtgctggtt
tacattcctcctcaggctgagctccggggtggctcctgggttgtgattgaccccaccatc
aacccccggcacatggagatgtatgctgaccgggaaagcaggggatcggttctggagcca
gaagggacagtagaaatcaaattccgcaaaaaggatctggtgaaaaccatgcgtcgggtg
gacccagtctacattagcttggctgagcgactgggcaccccagagctaagcccagttgag
cggaaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatttaccat
caggtagccgttcagtttgctgacttgcacgatacaccaggccggatgcaggagaagggt
gttattaacgacattctggattggaaaacatcccgtaccttcttctactggcggctgagg
cgtctcttgctggaggacctggtcaaaaagaaaatccacaatgccaacccagagctcacc
gatggtcagatccaggccatgttaaggcgctggtttgtagaagtggaaggaactgtgaag
gcctatgtttgggacaataacaaggatctggtggagtggctggagaaacagctaactgag
gaagatggcgctcgctcagtaattgaggaaaacatcaaatacatcagtagagactatgtc
ctcaagcagatccgcagcttggtacaggccaatcccgaggttgccatggattccatcgtc
catatgacccagcacatctcacccactcagcgagcagaagtcgtacggatcctctccacg
atggactccccttcaacatag
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integrated database retrieval system