Heterocephalus glaber (naked mole-rat): 101721263
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Entry
101721263 CDS
T02812
Symbol
Tyms
Name
(RefSeq) thymidylate synthetase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00240
Pyrimidine metabolism
hgl00670
One carbon pool by folate
hgl01100
Metabolic pathways
hgl01232
Nucleotide metabolism
hgl01523
Antifolate resistance
hgl04981
Folate transport and metabolism
Module
hgl_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
101721263 (Tyms)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101721263 (Tyms)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101721263 (Tyms)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101721263 (Tyms)
Enzymes [BR:
hgl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
101721263 (Tyms)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
101721263
NCBI-ProteinID:
XP_004853235
UniProt:
A0A0P6J905
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Position
Un
AA seq
310 aa
AA seq
DB search
MPAPGSQLPPPPAAHDQGAKPSAPHAELQYLRQVEHILQSGFRKEDRTGTGTLSLFGMQA
RYSLRDQFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGF
SSRQEGDLGPVYGFQWRHFGADYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWN
PKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMVAHVTGL
QPGDFVHTLGDAHIYLNHIEPLKTQLQREPRPFPKLKILRTVETIDNFTAEDFQLEGYNP
HPAIKMEMAV
NT seq
933 nt
NT seq
+upstream
nt +downstream
nt
atgcccgcccccggctctcagctcccgccaccgcccgccgcgcacgaccagggcgcgaag
ccctcggcgccgcacgcggagctgcagtacctgcggcaggtggagcacatcctgcagagc
ggctttcgcaaggaggaccgcacgggcaccgggacgctgtcgctgttcggcatgcaggcg
cgctacagcctgcgagatcagtttcccctgctgaccaccaagcgtgtgttctggaagggt
gttttggaggagctgctgtggtttatcaagggatccacaaacgccaaagaactgtcttcc
aagggcgtgaagatctgggatgccaatgggtcccgagacttcctggacagcctggggttt
tccagccgccaggaaggggacctgggtcccgtgtatggcttccagtggaggcattttggg
gctgactacaaagatatggactcagattactcgggtcagggagtggaccagctgcagaaa
gtgattgacaccatcaaaaccaaccctgatgacagaagaatcatcatgtgcgcctggaac
ccaaaagacctccctctgatggcgctgcctccctgccatgccctctgccagttctacgtg
gtgaacggagagctgtcctgccagctgtaccagcgctccggggacatgggcctgggcgtg
cccttcaacattgccagctacgccctgctcacctacatggtcgcccacgtcactggcctg
cagccaggtgactttgtacatactttgggagatgcacatatttacctgaatcacattgag
ccactgaaaactcagcttcagcgagaaccaagacctttcccaaagctcaaaatccttcga
acagttgagaccatcgacaacttcacagctgaagactttcagctggaagggtacaatcca
catcctgccattaagatggaaatggctgtgtag
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