KEGG   Halorarum salinum: HUG12_12080
Entry
HUG12_12080       CDS       T06744                                 
Symbol
thyA
Name
(GenBank) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
halu  Halorarum salinum
Pathway
halu00240  Pyrimidine metabolism
halu00670  One carbon pool by folate
halu01100  Metabolic pathways
halu01232  Nucleotide metabolism
halu04981  Folate transport and metabolism
Module
halu_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:halu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    HUG12_12080 (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HUG12_12080 (thyA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    HUG12_12080 (thyA)
Enzymes [BR:halu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     HUG12_12080 (thyA)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-ProteinID: QLG62427
UniProt: A0A7D5LBB3
LinkDB
Position
2455363..2456364
AA seq 333 aa
MQQYLDLVERVLRTGTYKPNRTGVDTLSSFAEGYEVDLAEGFPLLTTKDLSGFRWNSLVH
EFLWYLSGEEHVRTLREETGIWDAWADEEGHLDTAYGRFWRRFPIPEEGLPGETWADEGH
RWVNDDERTFDQIQYVLDTLRENPNSRRIVVNAWHPANATVSTLPPCHYTFVFNVQGDRL
NLQLVQRSGDIALGVPFNVAAYSLLLTAVAQRTGFEPGTFAHTVTDAHVYCGSGDRGAWY
GSHGDDLADRLADVTERAEYREVADWVEREAPPEADGEEDMDHVPGLLRQLSREPRERPR
IEVADRPLDELTYDDVRLREYDPAEGIRFAVAE
NT seq 1002 nt   +upstreamnt  +downstreamnt
atgcaacagtacctcgacctcgtcgagcgcgtcctcaggaccgggacgtacaagccgaac
cgaaccggggtcgacacgctctcctcgttcgccgaggggtacgaggtcgacctcgccgag
gggttccccctcctgacgacgaaggacctctccgggttccgctggaactcgctcgtccac
gagttcctctggtacctctccggcgaggagcacgtccggaccctccgcgaggagacgggc
atctgggacgcctgggccgacgaggagggccacctcgacaccgcctacgggcgcttctgg
cgccgctttcccatccccgaggaggggctgccgggcgagacgtgggccgacgagggccac
cgctgggtgaacgacgacgagcgtacgttcgaccagatacagtacgtcctcgacacgctc
cgggagaaccccaactcgcggcgaatcgtcgtgaacgcctggcaccccgcgaacgcgacc
gtctcgacgctcccgccgtgtcactacaccttcgtcttcaacgtccagggcgaccggctg
aacctccagctcgtccagcgctcgggcgacatcgcgctcggcgtcccgttcaacgtcgcc
gcctactcgctgctgctcacggccgtcgcccagcgcaccgggttcgaacccggcaccttc
gcccacaccgtcaccgacgcgcacgtctactgcgggagcggcgaccgcggggcctggtac
ggcagccacggcgacgacctcgccgacagactcgcggacgtgaccgagcgcgcggagtac
cgggaggtcgccgactgggtcgagcgcgaggcgcccccggaagccgacggcgaggaggac
atggaccacgtccccggcctgctccgccaactctcgcgggagccccgcgagcggccgcga
atcgaggtcgccgacaggcccctcgacgagttgacgtacgacgacgtccgcctgcgcgag
tacgaccccgccgaaggcatccggttcgcggtcgccgagtga

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