KEGG   Eurypyga helias (sunbittern): 104502802
Entry
104502802         CDS       T08356                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
ehs  Eurypyga helias (sunbittern)
Pathway
ehs00670  One carbon pool by folate
ehs01100  Metabolic pathways
ehs01240  Biosynthesis of cofactors
ehs04981  Folate transport and metabolism
Module
ehs_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ehs00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    104502802 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    104502802 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ehs04147]
    104502802 (MTHFD1)
Enzymes [BR:ehs01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     104502802 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     104502802 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     104502802 (MTHFD1)
Exosome [BR:ehs04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   104502802 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall
Other DBs
NCBI-GeneID: 104502802
NCBI-ProteinID: XP_010150555
LinkDB
Position
Unknown
AA seq 708 aa
QVRERLKKQVVEMKEKFPGFRPGLAILQVGNRDDSNLYINMKLKAAAEIGISANHIKLPN
TATEADVLKCIASLNGDPAVHGFIVQLPLDSDKPINTEKITNAVAPEKDVDGLSSINAGK
LSRGDLGDCFIPCTPKGCMELIRQTGIQVAGKRAVVVGRSKIVGAPMHDLLLWNHATVTT
CHSKTSTLAEEVGKADILVVAAGKAEMVKGEWIKPGAVVIDCGINHVPDSTKASGKRVVG
DVAYSTAKEKASYITPVPGGVGPMTVAMLMQSTVESAQRFLEKFEPGKWNIQYNQLTLKI
PVPSDIEISQSYMPKPIDQVAKEVGLLPDEVELYGQTKAKVHLSALERLKNQPDGKYVVV
TGITPTPLGEGKSTTTVGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYCQVIP
MEEFNLHLTGDIHAITAANNLVAAAVDARIFHELTQTDQAFYNRLVPSVSGVRKFSDIQI
RRLQKLGINKTDPMALTKEEINSFVRLDIDPSTITWQRVLDTNDRFLRKITIGQSPTEKG
FSRTAQFDITVSSEIMAVLALSDGLDDMKKRLGRMVVASSKRGEPVTADDLGVTGALAVL
MKDALKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGAD
IGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPAVSTQQGFLWA
NT seq 2128 nt   +upstreamnt  +downstreamnt
acaagtgagagagagactaaagaagcaagttgttgagatgaaagagaaatttccaggctt
cagaccaggactcgcaatattgcaggttggaaatcgggatgattcaaacctctacattaa
tatgaagctgaaggctgctgctgagattgggatcagtgccaatcacataaaactgccaaa
cacagcaacagaagctgatgtcctcaagtgcattgcctccttgaatggagaccctgctgt
tcatggctttatagtgcagctgccacttgactctgataaacccatcaataccgaaaaaat
aaccaatgctgttgcacctgagaaggatgtagatggcttaagtagcatcaatgctgggaa
actctctagaggggaccttggagactgctttattccctgcacgccaaaaggatgcatgga
acttatcaggcagacaggcatccaggttgcagggaaaagagctgtagtggttggtcgcag
taagatcgttggtgctcccatgcatgacctgctgctctggaatcacgcaacagtaaccac
ttgccattctaagacctcaaccctggctgaggaggttggtaaagccgatatcctggtggt
tgcagctggtaaagctgaaatggtaaaaggtgaatggatcaaacctggtgcagtcgtaat
agactgtggaattaaccatgtgccagacagcacaaaggccagtggaaaaagagttgtagg
agatgtggcatacagtacagcaaaggaaaaagcttcctacatcaccccagttcctggcgg
cgttgggcctatgactgtggccatgttaatgcagagcacagtggagagtgcacaacgttt
tctggaaaagtttgagcctggaaaatggaacatccagtataatcagcttaccctaaagat
tcctgttccaagtgatattgaaatatcgcagtcttacatgccaaagcctattgatcaagt
tgcaaaagaagttggcctgctccctgatgaggtggagctgtacggccaaactaaagccaa
ggttcatctgtcagctctggaacggctgaagaaccagccagatggcaaatatgtcgttgt
tactgggataactcctactcccctgggagagggtaaaagcaccaccactgtcggtcttgt
tcaagccttaggagcacaccttcaccagaatgtctttgcctgtgttcgtcagccttctca
agggccaacctttggtataaaaggtggagctgcaggtggtggctattgtcaagttatccc
catggaagagtttaaccttcacctcactggtgacatccatgctatcactgcagccaacaa
cctggtagctgctgctgttgatgcacgtatattccatgagctaactcagactgatcaggc
tttctacaaccgtttggtgccttctgtcagtggtgttaggaagttctcagacattcagat
tcgaagactgcagaaattgggcattaacaaaaccgatcctatggctttgacaaaggaaga
aataaactcatttgtgagactggacattgacccaagcaccataacatggcaaagagtact
ggatacaaatgacaggttcctcaggaaaatcactattggacagtctccaacagaaaaagg
cttctcacgaacggctcagtttgatatcacggtgagcagtgaaatcatggcagttctagc
gctctctgatgggttggatgatatgaaaaagcgactgggcagaatggttgtagcctccag
caagagaggagaaccagttacagcagatgaccttggagtgactggtgctctggctgtctt
gatgaaagatgctcttaaaccaaacctcatgcagacgctagagggaacaccagtgtttgt
tcatgccggacctttcgcaaatattgcacatgggaattcttcagtgttggcagacaaaat
agcactgaagcttgtgggtgaagaggggtttgttgttacagaagcaggatttggtgcaga
cataggcatggagaaattctttaatattaagtgccgctattctggtctccggcctcatgt
ggtggtgttggttgctacagtgcgagctctgaaaatgcatggaggagggcctgcagtaag
tactcagcaaggttttctttgggcctga

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