Escherichia coli O157 H7 Sakai (EHEC): ECs_3684
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Entry
ECs_3684 CDS
T00048
Symbol
thyA
Name
(RefSeq) thymidylate synthetase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00240
Pyrimidine metabolism
ecs00670
One carbon pool by folate
ecs01100
Metabolic pathways
ecs01232
Nucleotide metabolism
ecs04981
Folate transport and metabolism
Module
ecs_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
ECs_3684 (thyA)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ECs_3684 (thyA)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ECs_3684 (thyA)
Enzymes [BR:
ecs01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
ECs_3684 (thyA)
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Motif
Pfam:
Thymidylat_synt
DUF5609
Motif
Other DBs
NCBI-GeneID:
916501
NCBI-ProteinID:
NP_311711
UniProt:
P0A886
Structure
PDB
PDBj
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All DBs
Position
complement(3686888..3687682)
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AA seq
264 aa
AA seq
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MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELL
WFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLK
NDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIAS
YALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIF
DYRFEDFEIEGYDPHPGIKAPVAI
NT seq
795 nt
NT seq
+upstream
nt +downstream
nt
atgaaacagtatttagaactgatgcaaaaagtgctcgacgaaggcacacagaaaaacgac
cgtaccggaaccggaacgctttccatttttggtcatcagatgcgttttaacctgcaggat
ggattcccgctggtgacaactaaacgttgccacctgcgttccatcatccatgaactgctg
tggtttctgcagggcgacactaacattgcttatctacacgaaaacaatgtcaccatctgg
gacgaatgggccgatgaaaacggcgacctcggaccagtgtatggtaaacagtggcgcgcc
tggccaacgccagatggtcgtcatattgaccagatcactacggtactgaaccagctgaaa
aacgacccggattcccgccgcattattgtttcagcgtggaacgtaggcgaactggataaa
atggcgctggcaccgtgccatgcattcttccagttctatgtggcagacggcaaactctct
tgccagctttatcagcgctcctgtgacgtcttcctcggcctgccgttcaacattgccagc
tacgcgttactggtgcatatgatggcgcagcagtgcgatctggaagtgggtgattttgtc
tggaccggtggcgatacgcacctgtacagtaatcatatggatcaaactcatctgcaatta
agccgtgaaccgcgtccgctgccgaagttgattatcaaacgtaaacccgaatccatcttc
gactaccgtttcgaagactttgagattgaaggctacgatccacatccgggcattaaagcg
ccggtggctatctaa
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