KEGG   Escherichia coli O157 H7 Sakai (EHEC): ECs_3684
Entry
ECs_3684          CDS       T00048                                 
Symbol
thyA
Name
(RefSeq) thymidylate synthetase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
ecs  Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00240  Pyrimidine metabolism
ecs00670  One carbon pool by folate
ecs01100  Metabolic pathways
ecs01232  Nucleotide metabolism
ecs04981  Folate transport and metabolism
Module
ecs_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ecs00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    ECs_3684 (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ECs_3684 (thyA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECs_3684 (thyA)
Enzymes [BR:ecs01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     ECs_3684 (thyA)
SSDB
Motif
Pfam: Thymidylat_synt DUF5609
Other DBs
NCBI-GeneID: 916501
NCBI-ProteinID: NP_311711
UniProt: P0A886
Structure
LinkDB
Position
complement(3686888..3687682)
AA seq 264 aa
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELL
WFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLK
NDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIAS
YALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIF
DYRFEDFEIEGYDPHPGIKAPVAI
NT seq 795 nt   +upstreamnt  +downstreamnt
atgaaacagtatttagaactgatgcaaaaagtgctcgacgaaggcacacagaaaaacgac
cgtaccggaaccggaacgctttccatttttggtcatcagatgcgttttaacctgcaggat
ggattcccgctggtgacaactaaacgttgccacctgcgttccatcatccatgaactgctg
tggtttctgcagggcgacactaacattgcttatctacacgaaaacaatgtcaccatctgg
gacgaatgggccgatgaaaacggcgacctcggaccagtgtatggtaaacagtggcgcgcc
tggccaacgccagatggtcgtcatattgaccagatcactacggtactgaaccagctgaaa
aacgacccggattcccgccgcattattgtttcagcgtggaacgtaggcgaactggataaa
atggcgctggcaccgtgccatgcattcttccagttctatgtggcagacggcaaactctct
tgccagctttatcagcgctcctgtgacgtcttcctcggcctgccgttcaacattgccagc
tacgcgttactggtgcatatgatggcgcagcagtgcgatctggaagtgggtgattttgtc
tggaccggtggcgatacgcacctgtacagtaatcatatggatcaaactcatctgcaatta
agccgtgaaccgcgtccgctgccgaagttgattatcaaacgtaaacccgaatccatcttc
gactaccgtttcgaagactttgagattgaaggctacgatccacatccgggcattaaagcg
ccggtggctatctaa

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