Equus caballus (horse): 100060971
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Entry
100060971 CDS
T01058
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00240
Pyrimidine metabolism
ecb00670
One carbon pool by folate
ecb01100
Metabolic pathways
ecb01232
Nucleotide metabolism
ecb01523
Antifolate resistance
ecb04981
Folate transport and metabolism
Module
ecb_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
100060971 (TYMS)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100060971 (TYMS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100060971 (TYMS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100060971 (TYMS)
Enzymes [BR:
ecb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
100060971 (TYMS)
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Gene cluster
GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
100060971
NCBI-ProteinID:
XP_001492275
Ensembl:
ENSECAG00000023203
VGNC:
24689
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All DBs
Position
8:44214810..44225447
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AA seq
312 aa
AA seq
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MPAFGSELQRPPSPPAARERGSEPRPHGELQYLGQIEHILRSGFRKEDRTGTGTLSVFGL
QARYNLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNANELSCKGVKIWDANGSRDFLDSL
GFSAREEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVINTIKTNPDDRRIILCA
WNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHIT
GLKPGDFVHTLGDAHIYLNHIDPLKTQLQREPRPFPKLKILRKVETIDDFKAEDFQLEGY
HPHPTIRMEMAV
NT seq
939 nt
NT seq
+upstream
nt +downstream
nt
atgccagccttcggctccgagctgcagcgcccgccgtcgccgcccgccgcgcgggagcgg
ggctcggaaccgcggcctcacggggagctgcagtacctggggcagattgagcacatcctg
cgctccggcttccggaaggaggaccgcacgggcaccggcaccctgtcggtgttcggcctg
caggcgcgctacaacctgagagatgaatttcctctgctgacaaccaaacgtgttttctgg
aagggtgtcttggaagagttgctgtggtttatcaagggatccacaaatgctaatgaactg
tcttgcaagggagtgaaaatctgggatgccaatgggtcccgagacttcttggacagcctg
ggattctccgccagagaagaaggggatttaggcccagtttacggctttcagtggaggcat
tttggggcagaatacaaagatatggattcagattattcaggtcaaggagtagaccaactg
caaaaagtgattaacacaatcaaaaccaaccctgacgacagaagaatcatcctgtgtgct
tggaatccaaaagatcttcctctcatggctctgcctccctgccatgccctctgccagttc
tacgtggtgaacggtgagctgtcctgccagctgtaccagagatcgggagacatgggcctg
ggtgtgcccttcaacattgccagctacgccctgctcacctacatgatcgcacacatcacg
ggcctgaagccgggtgactttgtgcacactttgggagatgcacatatttacctgaatcac
attgacccgctgaaaacgcagcttcagcgagaaccaaggcctttcccgaaactcaaaatc
cttcgaaaagttgagacaattgatgacttcaaggctgaagactttcagcttgaagggtac
catccacacccgaccatcagaatggaaatggctgtttag
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