KEGG   Equus caballus (horse): 100060971
Entry
100060971         CDS       T01058                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00240  Pyrimidine metabolism
ecb00670  One carbon pool by folate
ecb01100  Metabolic pathways
ecb01232  Nucleotide metabolism
ecb01523  Antifolate resistance
ecb04981  Folate transport and metabolism
Module
ecb_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    100060971 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100060971 (TYMS)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100060971 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100060971 (TYMS)
Enzymes [BR:ecb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     100060971 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 100060971
NCBI-ProteinID: XP_001492275
Ensembl: ENSECAG00000023203
VGNC: 24689
LinkDB
Position
8:44214810..44225447
AA seq 312 aa
MPAFGSELQRPPSPPAARERGSEPRPHGELQYLGQIEHILRSGFRKEDRTGTGTLSVFGL
QARYNLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNANELSCKGVKIWDANGSRDFLDSL
GFSAREEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVINTIKTNPDDRRIILCA
WNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHIT
GLKPGDFVHTLGDAHIYLNHIDPLKTQLQREPRPFPKLKILRKVETIDDFKAEDFQLEGY
HPHPTIRMEMAV
NT seq 939 nt   +upstreamnt  +downstreamnt
atgccagccttcggctccgagctgcagcgcccgccgtcgccgcccgccgcgcgggagcgg
ggctcggaaccgcggcctcacggggagctgcagtacctggggcagattgagcacatcctg
cgctccggcttccggaaggaggaccgcacgggcaccggcaccctgtcggtgttcggcctg
caggcgcgctacaacctgagagatgaatttcctctgctgacaaccaaacgtgttttctgg
aagggtgtcttggaagagttgctgtggtttatcaagggatccacaaatgctaatgaactg
tcttgcaagggagtgaaaatctgggatgccaatgggtcccgagacttcttggacagcctg
ggattctccgccagagaagaaggggatttaggcccagtttacggctttcagtggaggcat
tttggggcagaatacaaagatatggattcagattattcaggtcaaggagtagaccaactg
caaaaagtgattaacacaatcaaaaccaaccctgacgacagaagaatcatcctgtgtgct
tggaatccaaaagatcttcctctcatggctctgcctccctgccatgccctctgccagttc
tacgtggtgaacggtgagctgtcctgccagctgtaccagagatcgggagacatgggcctg
ggtgtgcccttcaacattgccagctacgccctgctcacctacatgatcgcacacatcacg
ggcctgaagccgggtgactttgtgcacactttgggagatgcacatatttacctgaatcac
attgacccgctgaaaacgcagcttcagcgagaaccaaggcctttcccgaaactcaaaatc
cttcgaaaagttgagacaattgatgacttcaaggctgaagactttcagcttgaagggtac
catccacacccgaccatcagaatggaaatggctgtttag

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