Escherichia coli BL21(DE3): ECD_04229
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Entry
ECD_04229 CDS
T00931
Symbol
hpaE
Name
(GenBank) 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase
KO
K00151
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:
1.2.1.60
]
Organism
ebl
Escherichia coli BL21(DE3)
Pathway
ebl00350
Tyrosine metabolism
ebl01100
Metabolic pathways
ebl01120
Microbial metabolism in diverse environments
ebl01220
Degradation of aromatic compounds
Module
ebl_M00533
Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
Brite
KEGG Orthology (KO) [BR:
ebl00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
ECD_04229 (hpaE)
Enzymes [BR:
ebl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
ECD_04229 (hpaE)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
ACT46010
UniProt:
A0A140NC89
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Position
complement(4506444..4507910)
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AA seq
488 aa
AA seq
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MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWANLPM
KERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNG
KTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTA
DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK
YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAE
RANRLRVGDPTDPNTQVGALISQQHWEKVSGYIRLGIEEGATLLVGGPDKPSDLPAHLKG
GNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVS
KVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD
HPIPKWGV
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaagtaaatcattggatcaacggcaaaaatgttgcaggtaacgactacttccag
accaccaatccggcaacgggtgaagtgctggcggatgtggcctctggcggtgaagcggag
atcaatcaggcggtagcggcagcgaaagaggcgttcccgaaatgggccaatctgccgatg
aaagagcgtgcgcgcctgatgcgccgtctgggcgatctgatcgaccagaacgtgccagag
atcgccgcgatggaaaccgcggacaccggcctgccgatccatcagaccaaaaatgtgttg
atcccacgcgcttctcacaactttgaatttttcgcggaagtctgccagcagatgaacggc
aagacctatccggttgacgacaagatgctcaactacacgctggtgcaaccggtaggcgtt
tgtgcgctggtatcgccgtggaacgtgccgtttatgaccgccacatggaaggtcgcgccg
tgtcttgcgctgggcaataccgcggtgctgaagatgtcggaactctccccgctgaccgct
gaccgcctgggtgagctggcgctggaagccggtattccggcgggcgtgctgaacgtggta
cagggctacggcgcaaccgcaggggatgcgctggttcgtcatcatgacgtacgtgccgtg
tcgttcaccggcggtacggccaccgggcgcaacatcatgaaaaacgccgggctgaaaaaa
tactccatggaactgggcggtaaatcgccggtgctgatttttgaagatgccgatattgaa
cgtgcgctggacgctgccctgttcaccatcttctcaatcaacggcgaacgctgcaccgcc
ggttcgcgcatttttattcaacagagcatctatccagaattcgttaaacgctttgccgaa
cgcgccaaccgtctgcgcgtgggcgatccgaccgatccgaatacccaggttggggcgctt
atcagccagcagcactgggaaaaagtctccggctatatccgtctaggcattgaagaaggc
gcaaccctgctggtgggcggtccggataaaccgtccgacctgcctgcgcacctgaaaggc
ggcaacttcctgcgcccaacggtgctggcggacgtagataaccgtatgcgcgttgcccag
gaagagattttcgggccggtcgcctgcctgctgccgtttaaagatgaagccgaaggctta
cgcctggcaaacgacgtggagtacggcctcgcgtcgtacatctggacacaggatgtcagc
aaagtgttacgcctggcgcgtggcattgaagcaggcatggtgttcgtcaacacccagaac
gtgcgcgacctgcgccagccgtttggcggcgtaaaagcctccggcaccgggcgtgaaggc
ggtgagtacagcttcgaagtgttcgcggaaatgaagaacgtctgcatttccatgggcgac
catccaattccaaaatggggagtctga
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