KEGG   Escherichia coli BL21(DE3): ECD_02675
Entry
ECD_02675         CDS       T00931                                 
Symbol
thyA
Name
(GenBank) thymidylate synthetase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
ebl  Escherichia coli BL21(DE3)
Pathway
ebl00240  Pyrimidine metabolism
ebl00670  One carbon pool by folate
ebl01100  Metabolic pathways
ebl01232  Nucleotide metabolism
ebl04981  Folate transport and metabolism
Module
ebl_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ebl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    ECD_02675 (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ECD_02675 (thyA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECD_02675 (thyA)
Enzymes [BR:ebl01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     ECD_02675 (thyA)
SSDB
Motif
Pfam: Thymidylat_synt DUF5609
Other DBs
NCBI-ProteinID: ACT44491
UniProt: A0A140N8Y2
LinkDB
Position
complement(2802642..2803436)
AA seq 264 aa
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELL
WFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLK
NDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIAS
YALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIF
DYSFEDFEIEGYDPHPGIKAPVAI
NT seq 795 nt   +upstreamnt  +downstreamnt
atgaaacagtatttagaactgatgcaaaaagtgctcgacgaaggcacacagaaaaacgac
cgtaccggaaccggaacgctttccatttttggtcatcagatgcgttttaacctgcaggat
ggattcccgctggtgacaactaaacgttgccacctgcgttccatcatccacgaactgctg
tggttcctgcagggcgacactaacattgcttatctacacgaaaacaatgtcaccatctgg
gacgaatgggccgatgaaaacggcgacctcgggccagtgtatggtaaacagtggcgcgcc
tggccaacgccagatggtcgtcatattgaccagatcactacggtactgaaccagctgaaa
aacgacccggattcgcgccgcattattgtttcagcgtggaacgtaggcgaactggataaa
atggcgctggcaccgtgccatgcattcttccagttctatgtggcagacggcaaactctct
tgccagctttatcagcgctcctgtgacgtcttcctcggcctgccgttcaacattgccagc
tacgcgttactggtgcatatgatggcgcagcagtgcgatctggaagtgggtgattttgtc
tggaccggtggcgatacgcacctgtacagcaatcatatggatcaaactcatctgcaatta
agccgcgaaccgcgtccgctgccgaagttgattatcaaacgtaaacccgaatccatcttc
gactacagtttcgaagactttgagattgaaggctacgatccgcatccgggcattaaagcg
ccggtggctatctaa

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